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| 1 | Overview of the phytomedicine approaches against Helicobacter pylori显示文摘Helicobacter pylori(H.pylori)successfully colonizes thehuman stomach of the majority of the human popula-tion.This infection always causes chronic gastritis,butmay evolve to serious outcomes,such as peptic ulcer,gastric carcinoma or mucosa-associated lymphoid tis-sue lymphoma.H.pylori first line therapy recommend-ed by the Maastricht-4 Consensus Report comprises theuse of two antibiotics and a proton-pomp inhibitor,butin some regions failure associated with this treatmentis already undesirable high.Indeed,treatment failure isone of the major problems associated with H.pylori in-fection and is mainly associated with bacterial antibioticresistance.In order to counteract this situation,someeffort has been allocated during the last years in theinvestigation of therapeutic alternatives beyond antibi-otics.These include vaccines,probiotics,photodynamic inactivation and phage therapy,which are briefly revis-ited in this review.A particular focus on phytomedicine,also described as herbal therapy and botanical therapy,which consists in the use of plant extracts for medicinal purposes,is specifically addressed,namely considering its history,category of performed studies,tested com-pounds,active principle and mode of action.The herbs already experienced are highly diverse and usually selected from products with a long history of employ-ment against diseases associated with H.pylori infec-tion from each country own folk medicine.The studies demonstrated that many phytomedicine products have an anti-H.pylori activity and gastroprotective action.Al-though the mechanism of action is far from being com-pletely understood,current knowledge correlates the beneficial action of herbs with inhibition of essential H.pylori enzymes,modulation of the host immune system and with attenuation of inflammation. | Filipa F Vale Monica Oleastro | 2014 | World Journal of Gastroenterology2014，20，19： | 13 |
| 2 | Helicobacter pylori infection- recent developments in diagnosis显示文摘Considering the recommended indications for Helicobacter pylori(H.pylori)eradication therapy and the broad spectrum of available diagnostic methods,a reliable diagnosis is mandatory both before and after eradication therapy.Only highly accurate tests should be used in clinical practice,and the sensitivity and specificity of an adequate test should exceed 90%.The choice of tests should take into account clinical circumstances,the likelihood ratio of positive and negative tests,the cost-effectiveness of the testing strategy and the availability of the tests.This review concerns some of the most recent developments in diagnostic methods of H.pylori infection,namely the contribution of novel endoscopic evaluation methodologies for the diagnosis of H.pylori infection,such as magnifying endoscopy techniques and chromoendoscopy.In addition,the diagnostic contribution of histology and the urea breath test was explored recently in specific clinical settings and patient groups.Recent studies recommend enhancing the number of biopsy fragments for the rapid urease test.Bacterial culture from the gastric biopsy is the gold standard technique,and is recommended for antibiotic susceptibility test.Serology is used for initial screening and the stool antigen test is particularly used when the urea breath test is not available,while molecular methods have gained attention mostly for detecting antibiotic resistance. | Ana Isabel Lopes Filipa F Vale Mónica Oleastro | 2014 | World Journal of Gastroenterology2014，20，28： | 12 |
| 3 | Autoimmune hepatitis and anti-tumor necrosis factor alpha therapy:A single center report of 8 cases显示文摘This article describes cases of anti-tumor necrosis factor(TNF)-α-induced autoimmune hepatitis and evaluates the outcome of these patients in relation to their immunosuppressive strategy. A retrospective analysis of medical records was performed in our center, in order to detect cases of autoimmune hepatitis(AIH) associated with anti-TNF biologic agents. We describe and analyze eight cases of AIH following anti-TNF therapy, 7 with infliximab and 1 with adalimumab. A distinction should be made between induction of autoimmunity and clinically evident autoimmune disease. Liver biopsy is useful in detecting the role of the TNF-α antagonist in the development of AIH. The lack of relapse after discontinuing immunosuppressive therapy favors, as in this case series, an immune-mediated drug reaction as most patients with AIH have a relapse after treatment is suspended. Although AIH related to anti-TNF therapy is rare, a baseline immunological panel along with liver function tests should be performed in all patients with autoimmune disease before starting biologics. | Susana Rodrigues Susana Lopes Fernando Magro Hélder Cardoso Ana Maria Horta e Vale Margarida Marques Eva Mariz Miguel Bernardes Joanne Lopes Fátima Carneiro Guilherme Macedo | 2015 | World Journal of Gastroenterology2015，21，24： | 9 |
| 4 | Feasibility of occipital condyle smvw placement for occipitocervical fixation: a cadaveric study and description of a novel technique显示文摘 | Uribe JS Ramos E Vale F | 2008 | J Spinal Dis- ord Tech2008，21，8： | 1 |
| 5 | Comparison of methods for estimating forest overstory cover: differences among techniques 显示文摘 | Bunnell F L Vales D J | 1990 | Can J For Res1990，20，： | 1 |
| 6 | The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p693-positive breast carcinomas 显示文摘 | Ribeiro-Silva A Becker de Moura H Ribeiro do Vale F | 2005 | Int J Biol Markers2005，20，4： | 1 |
| 7 | An electric energy consumer characterization framework based on data mining techniques 显示文摘 | FIGUEIREDO V RODRIGUES F VALE Z | 2005 | IEEE Transactions on Power Systems2005，20，2： | 1 |
| 8 | Bidimensional codes recorded on an oxide glass surface u- sing a continuous wave CO2 laser显示文摘 | ANDREETA M R B CUNHA L S VALES L F | 2011 | J Micromeeh Mi- croeng2011，21，02： | 1 |
| 9 | Stabilizatien/solidification of a municipal solid waste incineration residue using fly ash-based geopolymers显示文摘 | GALIANO Y L PEREIRA C F VALE J | 2011 | Journal of Hazardous Materials2011，，185： | 1 |
| 10 | Accumulation of Zn, Pb, Cu, Cr and Ni in sediments between roots of the Tagus estuary salts marshes, Portugal 显示文摘 | Carador I Vale C Catarino F | 1996 | Estums i Coast and Shelf Sci1996，42，4： | 1 |
| 11 | Effects of rice growth stages and silicon on sheath blight development 显示文摘 | Rodrigues F A Vale F X R Datnoff L E | 2003 | Phytopathology2003，93，： | 1 |
| 12 | Better KBS for Real-time Applications in Power System Control Centers: The Experience of the SPARSE Project显示文摘 | Vale Z A Ferandes M F | 1998 | Computers in Industry1998，37，： | 1 |
| 13 | Gene therapy with VEGF for inoperable coronary artery disease显示文摘 | Symes J F Losordo D W Vale P R | 1999 | Ann Thorac Surg1999，68，3： | 1 |
| 14 | Analytical and numerical solution of no-stationary state of stress in a thin viscoelastic plate显示文摘 | Adamek V Vales F Las V | 2005 | Nonlinear Analysis2005，63，： | 1 |
| 15 | Primaquine dipep-tide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs显示文摘 | Vale N Nogueira F do Rosário VE | 2009 | Eur J Med Chem2009，44，6： | 1 |
| 16 | Development of methods for the determination of cadmium and thallium in oil shale by products with graphite furnace atomic absorption spectrometry using direct analysis显示文摘 | Helen R Oliveira Marcia F Mesko Maria Goreti R Vale | 2014 | Microchemical Journal2014，116，： | 1 |
| 17 | Particle formation in vinyl chloride emulsion polymerization:reaction modeling显示文摘 | Vale H M McKenna T F | 2009 | Ind Eng Chem Res2009，48，： | 1 |
| 18 | Solidification/stabilization of electric arc furnace dust using coal fly ash 显示文摘 | PEREIRA C F RODRIGUEZ-PINERO M VALE J | 2001 | Journal of Hazardous Materials2001，82，： | 1 |
| 19 | Co-Administration of Onda- nsetron Decreases the Analgesic Efficacy of Tramadol in Humans 显示文摘 | Vale C Oliveira F Assuno J | 2011 | Pharmacology2011，88，34： | 1 |
| 20 | Influence of silhcom on sheath blight of rice in brazil 显示文摘 | Rodribues F A Vale F X R Korndorfer G H | 2003 | Crop Protection2003，22，1： | 1 |
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