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| 1 | Diabetes--Role of epigenetics,genetics,and physiological factors显示文摘Cells of organ systems are endowed with a relatively similar genome while epigenome niches keep varying chronologically and defined explicitly in the respective tissues.The genome of an individual is always influenced by parental,embryonic,tissue-specific,and environmental epigenomes and the same must have been the possible reason for invariable inquiries relating to familial,environmental and life style patterns in the preliminary investigations of diabetic complications.Unprecedented methylation of lysine residues of histones and cytosines of CpG islands of promoter DNA impede the transcription of genes and homocysteine is the metabolic key player of methyl groups.Gck and COX7A1 are the 2 examples in the present review to elucidate the epigenetic influence on the onset of diabetes.miRNAs are additional promising cellular components influencing both at transcriptional and translational levels and promoting either in favour or against(i.e.,feed back) TFs,signaling factors and proteins through their pliotropic effects and thus are reported to regulate cellular physiology.miR-124a and miR-9 are primarily endemic to nervous tissue and they are now being exploited in islets for their function in executing exocytosis of insulin,which of course is one of the fundamental canons of diabetes.miR-375 persuades beta cells for glucose-induced insulin gene expression.The current approach to evaluate the constellation of genes and their products involved in diabetes in huge number of samples through GWA studies may unravel intricacies involved in the management of diabetes and its associated consequences. | Sreerama Krupanidhi Saikiran K. Sedimbi Ganesan Vaishnav Sreerama Sai Madhukar Carani B. Sanjeevi | 2009 | 中南大学学报(医学版)2009，34，9： | 3 |
| 2 | Liquid peroxidation-derived reactive aldehydes directly and differentially impair spinal cord and brain mitochondrial function显示文摘 | Vaishnav RA Singh IN Miller DM | 2010 | J Neurotrauma2010，14，： | 1 |
| 3 | Relation between heart rate variability early after acute myocardial infarction and longterm mortality显示文摘 | Vaishnav S Stevenson R Marchant B | 1994 | Am J Cardiol1994，73，9： | 1 |
| 4 | Relation between heart rate variability early after acute myocardial infarction and long termmortality显示文摘 | Vaishnav S Stevenson R Marchant B | 1994 | Am J Cardiol1994，73，9： | 1 |
| 5 | Antioxidant therapies fortraumatic brain injury显示文摘 | Hall E D Vaishnav R A Mustafa A G | 2010 | Neurotherapeutics2010，7，1： | 1 |
| 6 | Structural characterization of the galactoxylomanan of cryptococcus neoformans Cap67 显示文摘 | Vaishnav V V Bacon BE Neill M Cherniak R | 2008 | Carbohydr Res2008，，： | 1 |
| 7 | Structural characte-rization of the galactoxylomanan of Cryptococcus neoformans Cap61 显示文摘 | Vaishnav V V Bacon B E 0* Neill M ef al | 1998 | Carbohyd1998，，306： | 1 |
| 8 | Temporal gene expression profiles of target-ablated olfactory epithelium in mice with disrupted expression of scavenger receptor A: impact on macrophages 显示文摘 | Getchell M L Li H Vaishnav R A | 2006 | Physiol Genomics2006，27，3： | 1 |
| 9 | Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells显示文摘 | Wei jzen S Rizzo P Braid M Vaishnav R Jonkheer S M Zlobin A | 2002 | Nat Med2002，8，： | 1 |
| 10 | Effects of lycopene on protein expression in human primary prostatic epithelial cells显示文摘 | Qiu X Yuan Y Vaishnav A | 2013 | Cancer Prey Res (Phila)2013，6，5： | 1 |
| 11 | Structural characterization of the galactoxylomannan of cryptococcus neoformans cap67显示文摘 | BACON BE O' NEILL M | 1998 | Carbohydrate Res1998，，306： | 1 |
| 12 | Raisins and additional walking have distinct effects on plasma lipids and inflammatory cy- tokines显示文摘 | Puglisi M J Mutungi G Vaishnav U | 2008 | 7(1): 142008，7，1： | 1 |
| 13 | Hyperuricemia and urate nephropathy in urate oxidase-deficient mice 显示文摘 | Wu X Wakamiya M Vaishnav S | 1994 | Proc Natl Acad SciUSA1994，91，2： | 1 |
| 14 | Structural characterization of the galatoxylomanan of Cryptococcus neoformansCap 67显示文摘 | Vaishnav V V Bacon B E Neill M | 2008 | Carbohydr Res2008，，： | 1 |
| 15 | Relation between Heart Rate Variability Early after Acute Myocardial Infarction and Long-term Mortality显示文摘 | Stevenson K Marchant B | 1994 | Am J Cardiol1994，73，9： | 1 |
| 16 | Cryptococcus neoformans and cryptococcal glucuronoxylomannan,galactoxylomannan, and mannoprotein induce different levels of tumor necrosis factor alpha in human peripheral blood mononuclear cells显示文摘 | Chaka W Verheul AF Vaishnav VV | 1997 | Infect Immun1997，65，1： | 1 |
| 17 | Genotypic variations and influence of diurnal temperature on cotton fiber development显示文摘 | Thaker V S Saroop S Vaishnav P P | | Field Crops Res0，22，： | 1 |
| 18 | Hurdle technology for shelf stable minimally processed French beans: a response surface methodology approach 显示文摘 | Gupta S Chatterjee S Vaishnav J | 2012 | LWT Food Science and Technology2012，48，2： | 1 |
| 19 | Hydrogels as controlled release devices in agriculture显示文摘 | Rudzinski W E Dave A M Vaishnav U H | 2002 | Designed Monomers and Polymers2002，5，1： | 1 |
| 20 | Dynamic anisotropic viscoelastic properties of the aorta in living dogs 显示文摘 | Patel D J Janicki J S Vaishnav R N | 1973 | Circulation Research1973，32，： | 1 |
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