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| 1 | Pharmacokinetics of eugenol in rainbow trout ( Oncorhynchus mykiss )显示文摘 | S.A. Guénette F.C. Uhland P. Hélie F. Beaudry P. Vachon | 2007 | Aquaculture2007，，1： | 2 |
| 2 | Building Transcription Factor Binding Site Models to Understand Gene Regulation in Plants显示文摘Transcription factors (TFs) are key cellular components that control gene expression. They recognize specific DNA sequences, the TF binding sites (TFBSs), and thus are targeted to specific regions of the genome where they can recruit transcriptional co-factors and/or chromatin regulators to fine-tune spatiotemporal gene regulation. Therefore, the identification of TFBSs in genomic sequences and their subsequent quantitative modeling is of crucial importance for understanding and predicting gene expression. Here, we review how TFBSs can be determined experimentally, how the TFBS models can be constructed in silico, and how they can be optimized by taking into account features such as position interdependence within TFBSs, DNA shape, and/or by introducing state-of-the-art computational algorithms such as deep learning methods. In addition, we discuss the integration of context variables into the TFBS modeling, including nucleosome positioning, chromatin states, methylation patterns, 3D genome architectures, and TF cooperative binding, in order to better predict TF binding under cellular contexts. Finally, we explore the possibilities of combining the optimized TFBS model with technological advances, such as targeted TFBS perturbation by CRISPR, to better understand gene regulation, evolution, and plant diversity. | Xuelei Lai Arnaud Stigliani Gilles Vachon Cristel Carles Cezary Smaczniak Chloe Zubieta Kerstin Kaufmann Francois Parcy | 2019 | Molecular Plant2019，12，6： | 2 |
| 3 | Low doses of dexamethasone decrease brain water content of collagenase-induced cerebral hematoma显示文摘 | Vachon P Moreau JP | 2003 | Can J Vet Res2003，67，2： | 1 |
| 4 | Validation of windvector retrieval from ERS-1 SAR images over the o-cean显示文摘 | VACHON P W DOBSON F W | 1996 | Global Atmos Ocean1996，5，2： | 1 |
| 5 | The prediction of the ther- mal conductivity of two and three phase solid heteroge- neous mixtures 显示文摘 | CHENG S C VACHON R I | 1969 | Int J Heat Mass Tran1969，3，12： | 1 |
| 6 | The prediction of the thermal conductivity of two and three phase solid heterogeneous mixtures显示文摘 | Cheng S C Vachon R I | 1969 | InternationalJournal of Heat and Mass Transfer1969，12，3： | 1 |
| 7 | Microwave remote sensing of tropical cyclones from space显示文摘 | KATSAROS K B VACHON P W IAU W T | 2002 | Journal Oceanogra phy2002，58，： | 1 |
| 8 | Evaluation of sodium 4-hydroxybenzoate as an hydroxyl radical trap using gas chromatography-mass spectrometry and high-performance liquid chromatography with electrochemical detection 显示文摘 | Ste-Marie L Boismenu D Vachon L Montgomery J | 1996 | Analytical Biochemistry1996，241，： | 1 |
| 9 | Ship Ddetection by the RADARSAT SAR: Validation of Detection Model Predictions显示文摘 | Vachon P W Campbell J Bjerklund C Dobson F | 1997 | Canadian Journal of Remote Sensing1997，23，1： | 1 |
| 10 | Generation of anti-DC-SIGN monoclonal antibodies capable of blocking HIV-1gpl20 binding and reactive on formalin-fixed tissue 显示文摘 | Canard B Vachon H Fontaine T | 2011 | Immunology Letters2011，135，12： | 1 |
| 11 | Trichomespecific expression of the tobacco (Nicotiana sylvestris)cembratrien-ol synthase genes is controlled by bothactivating and repressing cis-regions显示文摘 | Ennajdaoui H Vachon G Giacalone C | 2010 | Plant Mol Biol2010，73，6： | 1 |
| 12 | Validation of Ship Detection by the Radarsat Synthetic Aperture Radar and the Ocean Monitoring Workstation显示文摘 | Vachon P W Thomas S J | 1999 | Canadian Journal of Remote Sensing1999，25，1： | 1 |
| 13 | Wind fields from SAR: Could they improve our understanding of storm dynam ics? 显示文摘 | KATSAROS K B VACHON P W BLACK P G | 2000 | Johns Hopkins APL Technical Digest2000，21，1： | 1 |
| 14 | Case-control study of increased mammo- graphic breast density response to hormone re- placement therapy显示文摘 | VACHON C M SELLERS T A VIERKANT R A | 2002 | Cancer Epidemiol Biomark- ers Prev2002，11，11： | 1 |
| 15 | Reciprocal expression of laminin A-chain isoforms along the crypt-villus axis in the human small intestine显示文摘 | Vachon P H | 1994 | Gastroenterology1994，106，4： | 1 |
| 16 | De l'utilité,en systématique,d'une nomenclature des dents des chélicères chez les Scorpions显示文摘 | VACHON M | 1963 | Bulletin du Muséum national d''Histoire naturelle Paris1963，35，2： | 1 |
| 17 | Proteinase - activated receptor - 1 mediates elastase - induced apoptosis of human lung epithelial cells显示文摘 | Suzuki T Moraes TJ Vachon E | 2005 | Am J Respir Cell Mol Biol2005，33，3： | 1 |
| 18 | Enzymatic conditions of an in vitro method to study protein di- gestion显示文摘 | GAUTHER S F VACHON C SAVOIE L | 1986 | Journal of Food Science1986，51，4： | 1 |
| 19 | Examination of traffic pollution distribution in a street canyon using the Nantes'99 experimental data and comparison with model results显示文摘 | BERKOWICZ R KETZEL M VACHON G | | 0，，： | 1 |
| 20 | The Era of Direct-Acting Antivirals Has Begun: The Beginning of the End for HCV?显示文摘 | Marie-Louise Vachon Douglas Dieterich | 2011 | Semin Liver Dis2011，，04： | 1 |
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