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| 1 | A型肉毒毒素治疗睑肌痉挛伴发睁眼性失用的疗效观察显示文摘目的探讨A型肉毒毒素治疗睑肌痉挛伴发睁眼性失用的疗效及安全性。方法对11例睑肌痉挛伴发睁眼性失用患者行局部A型肉毒毒素注射治疗,每14周1次,共3次。观察每次注射后起效时间、疗效持续时间及不良反应,并在每次注射后第3周根据改良痉挛性斜颈量表Ⅰ(TWSTRSⅠ)由固定医师对患者进行功能性评定,依据TWSTRSⅡ由患者进行生活残疾自评。结果治疗后平均(3.21±1.88)d起效,疗效持续(11.55±2.11)周。3次治疗的功能改善率分别为89.09%、87.27%、88.18%;3次治疗前TWSTRSⅡ评分分别为22.36±4.03、20.27±3.77及20.77±3.77,治疗3周后分别为7.55±4.44、8.00±5.25、9.27±4.98,治疗前后比较差异有极显著性(均P<0.01)。主要不良反应为睑下垂、疼痛烧灼感,但程度轻,多在48h内自行缓解。结论A型肉毒毒素局部注射可以改善患者的痉挛症状及日常生活能力,治疗原发性睑肌痉挛伴发睁眼性失用安全有效。 | 吴逸雯 Vial C Broussolle E 谢晶 陈生弟 | 2006 | 临床神经病学杂志2006，19，3： | 2 |
| 2 | Effect of alcohol addition in gas hold-up,liquid velocity and mass transfer in split-rec- tangular airlift bioreaetor 显示文摘 | E1 Azher N Gourich B Vial C | 2005 | Biochem Eng J2005，23，： | 1 |
| 3 | Pseudo-allergic drug reactions with special reference to direct histamine release显示文摘 | Descotes J Payen C Vial T | 2007 | Perspect Exp Clin Immunotoxicol2007，，： | 1 |
| 4 | Burkholderia diversity and versatility : an inventory of the extracellular products 显示文摘 | Vial L Groleau M C Dekimpe V | 2007 | Journal of Microbiology and Biotechnology2007，17，9： | 1 |
| 5 | Novel route layed double hydroxidespreparation by enzymatic decomposition of urea显示文摘 | Vial S Prevot V Forano C | 2006 | Journal of Physics and Chemistry of Solids2006，67，： | 1 |
| 6 | Smooth muscle does not have a common P2X receptor phenotype:expression,ontogeny and function of P2x1 receptors in mouse ileum,bladder and reproductive systems显示文摘 | Vial C Evans RJ | 2001 | Auton Neurosci2001，92，12： | 1 |
| 7 | Management of triple negative breast cancer显示文摘 | Oakman C Viale G Leo AD | 2010 | Breast2010，19，5： | 1 |
| 8 | Southwestern internal medicine conference: cigarette smoking and lung disease显示文摘 | VIAL W C | 1986 | Am J Med Sci1986，291，： | 1 |
| 9 | Influence of coalescence behaviour of the liquid and of gas sparging on hydrodynamics and bubble characteristics in a bubble column 显示文摘 | CAMARASA E VIAL C PONCIN S | 1999 | Chem Eng Proces1999，38，： | 1 |
| 10 | Management of triple negative breast cancer显示文摘 | Oakman C Viale G Di Leo A | 2010 | Breast2010，19，5： | 1 |
| 11 | Oncogene ab- lation- resistant pancreatic cancer cells depend on mito- chondrial function 显示文摘 | Viale A Pettazzoni P Lyssiotis C A | 2014 | Nature2014，514，7524： | 1 |
| 12 | Maintenance triple immunosuppression with cyclosporin A,mycophenolate sodium and steroids allows prolonged survival of primate recipients of hDAF porcine renal xenografts显示文摘 | Cozzi E Vial C Ostlie D | 2003 | Xenotransplantation2003，10，4： | 1 |
| 13 | Exercise test in muscle channelopathies and other muscle disorders 显示文摘 | KUNTZER T FLOCARD F VIAL C | 2000 | Muscle Never2000，23，： | 1 |
| 14 | Life supporting function for over one month of a transgenic porcine heart in a baboon显示文摘 | Vial C M Ostlie D J Bhatti F N | 2000 | J Heart Lung Transplant2000，19，2： | 1 |
| 15 | Management of triple negative breast cancer显示文摘 | Oakman C Viale G Di Leo A | 2010 | Breast2010，19，5： | 1 |
| 16 | A randomized trial of low-dose tamoxifen on breast cancer proliferation and blood estrogenic biomarkers 显示文摘 | Decensi A Robertson C Viale G | 2003 | J Natl Cancer Inst2003，95，11： | 1 |
| 17 | Molecular properties of ATP-gated P2X receptor ion channels显示文摘 | Vial C Roberts JA Evans RJ | 2004 | Trends Pharmacol Sci2004，25，9： | 1 |
| 18 | Analgesia in patients with acute abdominal pain 显示文摘 | Manterola C Vial M Moraga J | | Cochrane Database Syst Rev0，19，00： | 1 |
| 19 | Electrodiagnostic assessment of neuromuscular junction disorders显示文摘 | Chauplannaz G Vial C | 2004 | Rev Med Liege2004，59，1： | 1 |
| 20 | Constitutively activated dystrophic muscle fibroblasts show a paradoxical response to TGF-beta and CTGF/CCN2显示文摘 | Mezzano V Cabrera D Vial C | 2007 | J Cell Commun Signal2007，1，34： | 1 |
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