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| 1 | 中年成人平均动脉压的体位改变与动脉硬度的关系:Framingham心脏研究显示文摘Torjesen A, Cooper LL, Rong J, Larson MG, Hamburg NM, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of arterial stiffness with postural change in mean arterial pressure in middle-aged adults:the Framingham heart study. Hyperten- sion,2017,69(4) :685-690.站立位血压稳定调节受损可导致不良结果,包括跌倒、晕厥和定向障碍。平均动脉压(meanarterialpressure,MAP)通常在站立位时增加,然而,站立位MAP增加不足或减少可能导致脑灌注减少。已有研究报道,在动脉硬度增加的老年人中存在体位性低血压,年轻至中年人MAP的体位性改变与动脉硬度的相关性尚未阐明。该研究分析了Framingham心脏研究第3代队列中的受试者3205人(女性1693人,占53%)的直立性血压反应和全面血液动力学数据。 | Torjesen A Cooper LL Rong J Larson MG Hamburg NM Levy D Benjamin EJ Vasan RS Mitchell GF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017,25,3: | 5 |
| 2 | 妊娠并发症及妊娠特点与未来血压升高风险的关系显示文摘妊娠特点与心血管病风险相关,但其与高血压或血压水平的独立关联仍不明确。该研究将瑞典医学出生登记与Vsterbotten(瑞典北部)干预研究数据相联系。纳入妊娠前无高血压的40岁经产女性15 896人,用线性回归和Logistic回归分析以前妊娠因素与血压水平及高血压的关系。妊娠因素包括胎次、首次分娩年龄、子痫前期、妊娠期糖尿病、胎盘早剥、小于胎龄儿(出生体质量〈相同胎龄儿第3百分位)或死胎。 | Parikh NI Norberg M Ingelsson E Cnattingius S Vasan RS Domellf M Jansson JH Edstedt Bonamy AK 赵狄 练桂丽 | 2017 | 中华高血压杂志2017,25,2: | 3 |
| 3 | 中年人对亚极量运动的血压反应与心血管事件和全因死亡率的关系:Framingham心脏研究显示文摘关于中年人对亚极量运动的血压反应与晚年发生心血管事件及死亡的关系的研究较少。该文研究者纳入Framingham后代研究参与者1 993人(女性占53.2%,平均年龄58岁),参与7个循环周期的运动并进行评估。使用多因素线性回归模型评估亚极量运动的血压反应与常见亚临床心血管病的相关性;使用Cox比例风险回归模型分析对亚极量运动的血压反应与高血压、心血管病和全因死亡发生率的相关性。血压恢复定义为运动血压-亚极量运动后3min血压。 | 周卫(译) 刘莉(摘/审校) Lee J Vasan RS Xanthakis V | 2020 | 中华高血压杂志2020,28,6: | 3 |
| 4 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009,,9: | 2 |
| 5 | Pericardial Fat, Visceral Abdominal Fat, Cardiovascular Disease Risk Factors, and Vascular Calcification in a Community-Based Sample: The Framingham Heart Study显示文摘 | Guido A. Rosito Joseph M. Massaro Udo Hoffmann Frederick L. Ruberg Amir A. Mahabadi Ramachandran S. Vasan Christopher J. O’Donnell Caroline S. Fox | 2008 | Circulation2008,,5: | 2 |
| 6 | 心电图QRS波持续时间和左室大小的横断面相关性:Framingham心脏研究 | Dhingra R. Ho Nam B. Benjamin E.J. R.S. Vasan 腾增辉 | 2005 | 世界核心医学期刊文摘(心脏病学分册)2005,0,8: | 2 |
| 7 | 载脂蛋白E及脂肪酸与脑卒中、冠状动脉粥样硬化性心脏病、死亡风险的关系显示文摘膳食脂肪对心血管健康和死亡率的作用仍然存在争议。由于载脂蛋白E(apolipoprotein E,APOE)是脂质运输和代谢的核心,研究者通过检测APOE—ε4基因型,评估了血浆脂肪酸与脑卒中、冠状动脉粥样硬化性心脏病(冠心病)、死亡风险之间的关系。 | 刘青 叶鹏 Satizabal CL Samieri C Davis-Plourde KL Voetsch B Aparicio HJ Pase MP Romero JR Helmer C Vasan RS Kase CS Debette S Beiser AS Seshadr Sudhai | 2018 | 中华高血压杂志2018,26,11: | 2 |
| 8 | MELD Score as a Predictor of Early Death in Patients Undergoing Elective Transjugular Intrahepatic Portosystemic Shunt (TIPS) Procedures显示文摘 | Aaron Montgomery Hector Ferral Rajiv Vasan Darren W. Postoak | 2005 | CardioVascular and Interventional Radiology2005,,3: | 2 |
| 9 | 循环脂肪因子与超声心动图测量的心脏结构和功能的关系:基于社区的队列研究显示文摘脂肪因子介导与肥胖相关的心脏代谢风险,但它们在肥胖相关心力衰竭的发病机制中的作用仍然不确定。von Jeinsen等调查了社区样本中循环脂肪因子浓度与超声心动图测量的心功能和结构指标之间的关联。研究纳入3514名Framingham心脏研究参与者(平均年龄40岁,53.8%为女性). | 刘莉 叶鹏 von Jeinsen B Short MI Xanthakis V Carneiro H Cheng S Mitchell GF Vasan RS | 2018 | 中华高血压杂志2018,26,8: | 2 |
| 10 | General Cardiovascular Risk Profile for Use in Primary Care: The Framingham Heart Study显示文摘 | Ralph B. D’Agostino Ramachandran S. Vasan Michael J. Pencina Philip A. Wolf Mark Cobain Joseph M. Massaro William B. Kannel | 2008 | Circulation2008,,6: | 2 |
| 11 | Changes in Arterial Stiffness and Wave Reflection With Advancing Age in Healthy Men and Women: The Framingham Heart Study显示文摘 | Gary F. Mitchell Helen Parise Emelia J. Benjamin Martin G. Larson Michelle J. Keyes Joseph A. Vita Ramachandran S. Vasan Daniel Levy | 2004 | Hypertension: Journal of the American Heart Association2004,,6: | 2 |
| 12 | Vitamin D Deficiency and Risk of Cardiovascular Disease显示文摘 | Thomas J. Wang Michael J. Pencina Sarah L. Booth Paul F. Jacques Erik Ingelsson Katherine Lanier Emelia J. Benjamin Ralph B. D?Agostino Myles Wolf Ramachandran S. Vasan | 2008 | Circulation2008,,4: | 2 |
| 13 | 父母心力衰竭与其子女心力衰竭风险的关联性显示文摘Background: The association between heart failure in parents and the prevalence of left ventricular systolic dysfunction and the risk of heart failure in their offspring has not been investigated in a community-based setting. Methods: We examined the cross-sectional association of heart failure in parents with the prevalence of left ventricular systolic dysfunction, as well as left ventricular mass, internal dimensions, and wall thickness, in 1497 participants of the Framingham Offspring Study(mean age, 57 years; 819 women) who underwent routine echocardiography. We also investigated prospectively whether heart failure in parents increased the risk of heart failure in 2214 offspring(mean age, 44 years; 1150 women). Results: As compared with the 1039 participants whose parents did not have heart failure, the 458 participants in the cross-sectional cohort who had at least one parent with heart failure were more likely to have increased left ventricular mass(17.0 percent vs. 26.9 percent), left ventricular internal dimensions(18.6 percent vs. 23.4 percent), and left ventricular systolic dysfunction(3.1 percent vs. 5.7 percent); the multivariable-adjusted odds ratios were 1.35(95 percent confidence interval, 0.99 to 1.84), 1.29(95 percent confidence interval, 0.96 to 1.72), and 2.37(95 percent confidence interval, 1.22 to 4.61), respectively. In the longitudinal cohort, heart failure developed in 90 offspring during follow-up(mean length of follow-up, 20 years). The age-and sex-adjusted 10-year incidence rates of heart failure were 2.72 percent among offspring with a parent with heart failure, as compared with 1.62 percent among those without a parent with heart failure. This increase in risk persisted after multivariable adjustment(hazard ratio, 1.70; 95 percent confidence interval, 1.11 to 2.60). Conclusions: Heart failure in parents is associated with an increased prevalence of left ventricular systolic dysfunction cross-sectionally and an elevated risk of heart failure longitudinally. Our data emphasize the contribution of familial factors to the heart-failure burden in the community. | Lee D.S. Pencina M.J. Benjamin E.J. R.S. Vasan 马超 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006,,12: | 2 |
| 14 | Abdominal Visceral and Subcutaneous Adipose Tissue Compartments: Association With Metabolic Risk Factors in the Framingham Heart Study显示文摘 | Caroline S. Fox Joseph M. Massaro Udo Hoffmann Karla M. Pou Pal Maurovich-Horvat Chun-Yu Liu Ramachandran S. Vasan Joanne M. Murabito James B. Meigs L Adrienne Cupples Ralph B. D’Agostino Christopher J. O’Donnell | 2007 | Circulation2007,,1: | 2 |
| 15 | The progression from hypertension to congestive heart failure 显示文摘 | Levy D Larson M G Vasan R S | 1996 | JAMA1996,275,20: | 1 |
| 16 | Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study; evidence for susceptibility loci on 1q显示文摘 | Dupuis J Larson M G Vasan R S | 2005 | Atherosclerosis2005,182,2: | 1 |
| 17 | Defining diastolic heart failure: a call for standardized diagnostic criteria显示文摘 | Vasan RS Levy D | 2000 | Circulation2000,101,: | 1 |
| 18 | Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction : the Framingham Heart Study 显示文摘 | VASAN R S SULLIVAN L M ROUBEN R | 2003 | Circulartion2003,107,11: | 1 |
| 19 | Impact of high-normal blood pressure on the risk of cardiovascular disease 显示文摘 | Vasan RS Larson MG Leip EP | 2001 | N Engl J Med2001,345,18: | 1 |
| 20 | Modified use of team-based learning for effective delivery of medical gross anatomy and embry- ology显示文摘 | Vasan NSI DeFouw DO Holland BK | 2008 | Anat Sci Educ2008,1,1: | 1 |