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| 1 | Nonlinear criterion for strength mobilization in brittle failure of rock and its extension to the tunnel scale显示文摘As underground excavations are getting deeper and field stresses increase, the behavior of intact rock blocks plays an increasingly important role in understanding and estimating the overall rock mass strength. To model the brittle behavior of intact rock blocks, the stress–strain curve is usually idealized considering a linear strength mobilization approach(cohesion-weakening-friction-strengthening, CWFS),however, it is well recognized that rock presents a nonlinear behavior in terms of the confining stress.This study extends the strength mobilization in brittle failure of rock using nonlinear criteria. To determine the model parameters, a standard statistical method that uses the complete laboratory stress–strain curves of the intact rock is employed. Several hypotheses of linear and nonlinear models are statistically compared for different types of rock and confining stress levels. Results demonstrate that the best approach to model the brittle failure of rock is to consider a nonlinear strength envelope, such as the Hoek-Brown criterion assuming a residual uniaxial compressive strength different from zero and a mi parameter that increases, both with simultaneous mobilization. This model helps to recreate highconfining conditions and a more realistic transition between peak and post-peak strength. The obtained parameters are discussed and compared with literature values to verify the validity and to develop guidelines for the estimation of parameters, providing an objective mobilization criterion. Finally, the nonlinear model was applied to a finite element code and extended to a tunnel scale in the brittle rock under high-stress conditions. A reasonable fit between the simulations and the in-situ overbreak measurements was found. | Rodolfo Cabezas Javier Vallejos | 2022 | International Journal of Mining Science and Technology2022，32，4： | 3 |
| 2 | Assessment of the plug flow and dead volume ratios in a sub-surface horizontal-flow packed-bed reactor as a representative model of a sub-surface horizontal constructed wetland显示文摘 | David Jafet Rodríguez Alcocer Germán Giácoman Vallejos Pascale Champagne | 2011 | Ecological Engineering2011，，： | 2 |
| 3 | GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer显示文摘Non-small cell lung cancer(NSCLC) is a heterogeneous disease accounting for approximately 85% of all lung cancers. Only 17% of patients are diagnosed at an early stage. Treatment is multidisciplinary and radiotherapy plays a key role in all stages of the disease. More than 50% of patients with NSCLC are treated with radiotherapy(curative-intent or palliative). Technological advancesincluding highly conformal radiotherapy techniques, new immobilization and respiratory control systems, and precision image verification systems-allow clinicians to individualize treatment to maximize tumor control while minimizing treatment-related toxicity. Novel therapeutic regimens such as moderate hypofractionation and advanced techniques such as stereotactic body radiotherapy(SBRT) have reduced the number of radiotherapy sessions. The integration of SBRT into routine clinical practice has radically altered treatment of early-stage disease. SBRT also plays an increasingly important role in oligometastatic disease. The aim of the present guidelines is to review the role of radiotherapy in the treatment of localized, locally-advanced, and metastatic NSCLC. We review the main radiotherapy techniques and clarify the role of radiotherapy in routine clinical practice. These guidelines are based on the best available evidence. The level and grade of evidence supporting each recommendation is provided. | Nuria Rodriguez De Dios Arturo Navarro-Martin Cristina Cigarral Rodolfo Chicas-Sett Rafael Garcia Virginia Garcia Jose Antonio Gonzalez Susana Gonzalo Mauricio Murcia-Mejia Rogelio Robaina Amalia Sotoca Carmen Vallejo German Valtuena Felipe Counago | 2022 | World Journal of Clinical Oncology2022，13，4： | 2 |
| 4 | Electron transfer across anodic films formed on tin in carbonate-bicarbonate buffer solution显示文摘 | C.A. Gervasi M.E. Folquer A.E. Vallejo P.E. Alvarez | 2004 | Electrochimica Acta2004，，5： | 2 |
| 5 | Value of Symptoms to Predict Tilt Testing Outcome in Patients with Clinical Suspicion of Vasovagal Syncope显示文摘 | Maite Vallejo Antonio G. Hermosillo Manlio F. Márquez Alma K. Urquidez Arturo Sotomayor Elizabeth Salas Manuel Cárdenas | 2007 | Archives of Medical Research2007，，5： | 2 |
| 6 | Nitrogen oxide emissions affected by organic fertilization in a non-irrigated Mediterranean barley field显示文摘 | Ana Meijide Lourdes García-Torres Augusto Arce Antonio Vallejo | 2009 | Agriculture, Ecosystems and Environment2009，，1： | 2 |
| 7 | Influence of pile shape and pile interaction on the crushable behavior of granular materials around driven piles: DEM analyses显示文摘 | Sebastian Lobo-Guerrero Luis E. Vallejo | 2007 | Granular Matter2007，，3： | 2 |
| 8 | Influence of pile shape and pile interaction on the crushable behavior of granular materials around driven piles:DEM analyses显示文摘 | GUERRERO S L VALLEJO L E | 2007 | Granular Matter2007，9，： | 1 |
| 9 | Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells显示文摘 | Vallejo D M Caparros E Dominguez M | 2011 | MBO J2011，30，4： | 1 |
| 10 | 显示文摘 | Ovalles C Vallejos C Vasquez T | 2003 | Petroleum Science and Technology2003，21，12： | 1 |
| 11 | 显示文摘 | Garcia Sanchez MV Lopez Vallejos P Perez deLuque D | 2004 | Rev Esp Enferm Dig2004，96，5： | 1 |
| 12 | Morphology and Mechanical Performance of Pregenerated and 'In-situ' PP/Vectra B Composites 显示文摘 | F J Vallejo J I Eguiazabal J Nazabal | 1999 | Polymer Engineering and Science1999，39，9： | 1 |
| 13 | IL - 6 promotes immune responses in human ulcerative colitis and induces a skin - homing phenotype in the dendritic cells and Tcells they stimulate 显示文摘 | D Bemardo S Vallejo - Diez ER Mann | 2012 | Eur J Inmmnol2012，42，5： | 1 |
| 14 | PACAP signaling to DREAM:a cAMP-dependent pathway that regulates cortical astrogliogenesis显示文摘 | Vallejo M | | 0，，： | 1 |
| 15 | Effect of tall oil fatty acids content on the properties of novel hyperbranched alkyd resins 显示文摘 | Murillo E A Vallejo P P Lopez B L | 2011 | Journal of Applied Polymer Science2011，120，6： | 1 |
| 16 | Perspectives in dryland restoration: approaches for climate change adaptation显示文摘 | VALLEJO V R SMANIS A CHIRINO E | 2012 | New Forests2012，43，56： | 1 |
| 17 | Effects of visnadine on rat isolated vascular smooth muscles显示文摘 | Durate J Vallejo I Perez -Vizcaino F | 1997 | Planta Med1997，63，3： | 1 |
| 18 | Incidental diagnosis of intradural lumbar disc herniation during discography:a case report显示文摘 | Benyamin R Vallejo R Yousuf N | 2007 | Pain Pract2007，7，4： | 1 |
| 19 | Early and intermediate Amadori glycosylation adducts,oxidative stress,and endothelial dysfunction in the streptozotocin-induced diabetic rats vasculature显示文摘 | Angulo J Vallejo S Peiro C | 2003 | Diabetologia2003，46，4： | 1 |
| 20 | Acytoplasmic male sterility-associated mitochondrial peptide in common bean is posttranslationally regulated显示文摘 | SARRIA R Lyznik A Vallejos C E | 1998 | Plant Cell1998，10，： | 1 |
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