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| 1 | Gastro-esophageal reflux disease symptoms are more common in general practice in Japan显示文摘AIM: To accurately assess the prevalence of GERD symptoms in general practice. METHODS: 4139 consecutive patients (2025 men and 2114 women with a mean age of 43 years), who fi rst attended the Outpatient Department of General Medicine and Emergency Care at Toho University Omori Hospital, were asked to respond to the F-scale questionnaire regardless of their chief complaints. The questionnaire is a self-report instrument, written in a simple and easy-to-understand language, containing 12 questions. RESULTS: Of 4139 subjects, 1554 patients (37.6%) were identifi ed as GERD according to their F-scale score (> 7). However, there were only 45 consultations (1.1%) for typical GERD symptoms. Although GERD symptoms are common in adults of all ages, the prevalence of GERD was highest in the 20-29 years age group and the age group 70-79 years had the lowest prevalence for both males and females. CONCLUSION: Although there was a high rate indicating GERD in our primary care population, only 1.1% of outpatients attended our hospital with a chief complaint of GERD symptoms. Since about one-third of GERD patients are affected by atypical symptoms, general physicians need to be cautious about extrapolating these results to patients with a chief complaint other than typical GERD symptoms. | Toshiyasu Watanabe Yoshihisa Urita Motonobu Sugimoto Kazumasa Miki | 2007 | World Journal of Gastroenterology2007，13，31： | 12 |
| 2 | Prevalence of linked angina and gastroesophageal reflux disease in general practice显示文摘AIM: To evaluate the association between gastroesophageal re? ux diseases (GERD) and coronary heart diseases. METHODS: One thousand nine hundred and seventy consecutive patients who attended our hospital were enrolled. All of the patients who first attend our hospital were asked to respond to the F-scale questionnaire regardless of their chief complaints. All patients had a careful history taken, and resting echocardiography (ECG) was performed by physicians if the diagnostic necessity arose. Patients with ECG signs of coronary artery ischemia were defined as STsegment depression based on the Minnesota code. RESULTS: Among 712 patients (36%) with GERD, ECG was performed in 171 (24%), and ischemic changes were detected in eight (5%). Four (50%) of these patients with abnormal findings upon ECG had no chest symptoms such as chest pain, chest oppression, or palpitations. These patients (0.6%; 4/712) were thought to have non-GERD heartburn, which may be related to ischemic heart disease. Of 281 patients who underwent ECG and did not have GERD symptoms, 20 (7%) had abnormal findings upon ECG. In patients with GERD symptoms and ECG signs of coronary artery ischemia, the prevalence of linked angina was considered to be 0.4% (8/1970 patients).CONCLUSION: The present study suggested that ischemic heart disease might be found although a patient was referred to the hospital with a complaint of GERD symptoms. Physicians have to be concerned about missing clinically important coronary artery disease while evaluating patients for GERD symptoms. | Hirohito Kato Takamasa Ishii Tatsuo Akimoto Yoshihisa Urita Motonobu Sugimoto | 2009 | World Journal of Gastroenterology2009，15，14： | 5 |
| 3 | Sporadic gastric carcinoid tumor successfully treated by two-stage laparoscopic surgery:A case report显示文摘We report a case of sporadic gastric carcinoid tumor successfully treated by two-stage laparoscopic surgery.A 38-year old asymptomatic woman was referred to our hospital for evaluation of a submucosal tumor of the stomach.Endoscopic examination showed a solitary submucosal tumor without ulceration or central depression on the posterior wall of the antrum and biopsy specimens were not sufficient to determine the diagnosis.Endoscopic ultrasound revealed a tumor nearly 2 cm in diameter arising from the muscle layer and a computed tomography scan showed the tumor enhanced in the arterial phase.Laparoscopic wedge resection was performed for definitive diagnosis.Pathologically,the tumor was shown to be gastric carcinoid infiltrating the muscle layer which indicated the probability of lymph node metastasis.Serum gastrin levels were normal.As a radical treatment,laparoscopy-assisted distal gastrectomy with regional lymphadenectomy was performed 3 wk after the initial surgery.Finally,pathological examination revealed no lymph node metastasis. | Takahiro Kinoshita Takashi Oshiro Tasuku Urita Yutaka Yoshida Mitsuru Ooshiro Shinichi Okazumi Ryoji Katoh Daisuke Sasai Nobuyuki Hiruta | 2010 | World Journal of Gastrointestinal Surgery2010，2，11： | 2 |
| 4 | Chitin and chitosan: functional biopolymers from marine crustaceaus显示文摘 | K URITA K | 2006 | Marine Biotechnology2006，8，3： | 1 |
| 5 | Evaluation of diaphragmatic hernia repair using PLGA mesh-col agen sponge hybrid scaffold:An experimental study in a rat model显示文摘 | Urita Y Komuro H Chen G | | 0，，09： | 1 |
| 6 | Perforation of the colon in neonates显示文摘 | Yasuhisa Urita Tetsuo Hori | 2005 | J Pediatr Surg2005，40，12： | 1 |
| 7 | Perforation of the colon in neonates显示文摘 | Komuro H Urita Y Hori T | 2005 | J Pediatr Surg2005，40，12： | 1 |
| 8 | Using serum pepsinogens wisely in a clinical practice显示文摘 | Miki K Urita Y | | 0，，01： | 1 |
| 9 | Hydraogen breath test as an indicator of the quality of colonic preparation for colonoscopy显示文摘 | URITA Y HIKE K | 2001 | The American Journal of Gastroenterology2001，96，9： | 1 |
| 10 | Effect of low-intensity pulsed ultrasound on bone healing at osteotomy sites after forearm bone shortening显示文摘 | Urita A Iwasaki N Kondo M Nishio Y Kamishima T Minami A | 2013 | J Hand Surg Am2013，38，： | 1 |
| 11 | Using serum pepsinogens wisely in a clinical practice显示文摘 | Miki K Urita Y | 2007 | J Dig Dis2007，8，1： | 1 |
| 12 | Using serum pepsinogens wisely in a clinical practice显示文摘 | Miki K Urita Y | 2007 | J Dig Dis2007，8，1： | 1 |
| 13 | Regeneration of the esophagus using gastric acellular matrix:an experimental study in a rat model显示文摘 | Urita Y Komuro H Chen G | 2007 | Pediatr Surg Int2007，23，1： | 1 |
| 14 | Effect of bifidobacterium bifidum fermented milk on helicobacter pylori and serum pepsinogen levels in humans 显示文摘 | MIKI K URITA Y ISHIKAWA F | 2007 | J Dairy Sci2007，90，6： | 1 |
| 15 | Evaluation of diaphragmatic hernia repair using PLGA mesh-col agen sponge hybrid scaffold:An experimental study in a rat model显示文摘 | Urita Y Komuro H Chen G | | 0，，09： | 1 |
| 16 | Continuous con- sumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psycho- logical symptoms in patients with functional gastrointesti- nal disorders 显示文摘 | Urita Y Goto M Watanabe T | 2015 | Biosci Microbiota Food Health2015，34，2： | 1 |
| 17 | Breath sample collection through the nostril reduces false-positive results of 13 C-urea breath test for the diagnosis of Helicobacter pylori infection显示文摘 | Y. Urita K. Hike N. Torii Y. Kikuchi E. Kanda H. Kurakata M. Sasajima K. Miki | 2004 | Digestive and Liver Disease2004，，10： | 1 |
| 18 | Direct evidence for atomic dejects in graphene layers 显示文摘 | Hashimoto A Suenaga K Gloter A Urita K Iijima S | 2004 | Nature2004，430，7002： | 1 |
| 19 | Regeneration of the esophagus using gastric acellular matrix:an experimental study in a rat model显示文摘 | Urita Y Komuro H Chen G | 2007 | Pediatr Surg Int2007，23，1： | 1 |
| 20 | Electrochemical property of LiMnPO_4nanocrystallite-embedded porous carbons as a cathode material of Li-ion battery显示文摘 | AONA S URITA K YAMADA H | 2012 | Solid State Ionics2012，225，： | 1 |
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