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| 1 | Differential expression of interleukin-1/Toll-like receptor signaling regulators in microscopic and ulcerative colitis显示文摘AIM:To investigate Toll-like receptor(TLR)signaling regulators in microscopic and ulcerative colitis patients.METHODS:Total RNA and microRNA were isolated from fresh frozen colonic biopsies of non-inflamed controls and patients with active or in-remission collagenous colitis(CC),lymphocytic colitis(LC),or ulcerative colitis(UC).We compared expressions of interleukin-1receptor-associated kinase(IRAK)-2,IRAK-M,interleukin(IL)-37,microRNA(miR)-146a,miR-155,and miR-21 using quantitative real time reverse transcription polymerase chain reaction.RESULTS:IRAK-M expression was increased in LC patients with active disease in histopathological remission(LC-HR;P=0.02)and UC patients(P=0.01),but no differences in IRAK-2 expression were detected compared to controls.miR-146a,-155 and-21 expressions were increased in LC-HR(P=0.04,0.07,and 0.004)and UC(P=0.02,0.04 and 0.03)patients.miR-146a and miR-21 expressions were significantly enhanced in UC patients compared to UC remission(UC-R;P=0.01and 0.04).Likewise,active CC patients showed significantly increased expression of miR-155(P=0.003)and miR-21(P=0.006).IL-37 expression was decreased in both CC(P=0.03)and LC(P=0.04)patients with a similar trend in UC patients but not statistically significant,whilst it was increased in UC-R patients compared to controls(P=0.02)and active UC(P=0.001).CONCLUSION:The identification of differentially expressed miRNAs,IL-37,and IRAK-M suggests different pathophysiologic mechanisms in various disease stages in LC,CC,and UC. | Sezin Gunaltay Nils Nyhlin Ashok Kumar Kumawat Curt Tysk Johan Bohr Olof Hultgren Elisabeth Hultgren Hornquist | 2014 | World Journal of Gastroenterology2014，20，34： | 11 |
| 2 | The Black-Scholes equation in sto- chastic volatility models显示文摘 | Ekstrom E Tysk J | 2010 | J Math Analy Appl2010，368，： | 1 |
| 3 | Acute pancreatitis induced by fluvastatin therapy显示文摘 | Tysk C A1-Eryani AY Shawabkeh AA | 2002 | J Clin Gastroenterol2002，35，5： | 1 |
| 4 | Acute pancreatitis induced by fluvastatin therapy 显示文摘 | Tysk C Al-Eryani AY Shawabkeh AA | 2002 | J Clin Gastroenterol2002，35，5： | 1 |
| 5 | Bubbles, convexity and the Black- Scholes equation 显示文摘 | Ekstrom E Tysk J | 2009 | Ann Appl Probab2009，19，： | 1 |
| 6 | Feynman-Kac formulas for Black-Schol- es-type operators 显示文摘 | Janson S Tysk J | 2006 | Bull London Math Soc2006，38，： | 1 |
| 7 | Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins:a study of heritability and the influence of smoking显示文摘 | Lindberg E Jarnerot G | 1988 | Gut1988，29，： | 1 |
| 8 | Antibody (IgG, IgA, and IgM) to baker's yeast (Saccharomyces cerevisiae), yeast mannan, gliadin, ovalbumin and betalactoglobulin in monozygotic twins with inflammatory bowel disease显示文摘 | Lindberg E Magnusson KE Tysk C | 1992 | Gut1992，33，7： | 1 |
| 9 | Microscopic colitis patients have increased proportions of Ki67 + proliferating and CD45RO + active/memory CD8 + and CD4 + 8 + mucosal T cells显示文摘 | Ashok Kumar Kumawat Hilja Strid Kristina Elgbratt Curt Tysk Johan Bohr Elisabeth Hultgren H?rnquist | 2012 | Journal of Crohn’s and Colitis2012，，： | 1 |
| 10 | Antibody (IgG, IgA, and IgM) to baker's yeast (Saccharomyces cerevisiae), yeast mannan, gliadin, ovalbumin and beta lactoglobulin in monozygotic twins with inflammatory bowel disease显示文摘 | Lindberg E Magnusson KE Tysk C | 1992 | Gut1992，33，7： | 1 |
| 11 | Is smoking a risk factor for collagenous colitis?显示文摘 | Lina Vigren Klas Sj?berg Cecilia Benoni Curt Tysk Johan Bohr Anders Kilander Lasse Larsson Magnus Str?m Henrik Hjortswang | 2011 | Scandinavian Journal of Gastroenterology2011，，11： | 1 |
| 12 | Appendectomy is followed by increased risk of Crohn's disease显示文摘 | Andersson RE Olaison G Tysk C | 2003 | Gastroenterology2003，124，1： | 1 |
| 13 | The aspect of natural resources in environmental impact statements for Swedish bioenergy plants 显示文摘 | Mats Eklund | 2002 | Journal of Environmental Assessment Policy and Management2002，4，1： | 1 |
| 14 | Prolonged postpartum course of intrahepatic cholestasis of pregnaney显示文摘 | Olsson R Tysk C Aldenbory F | 1993 | Gastroenterol1993，105，1： | 1 |
| 15 | Appendectomy is followed by increased risk of Crohn's disease显示文摘 | Andersson RE Olaison G Tysk C | 2003 | Gastroenterology2003，124，1： | 1 |
| 16 | Appendectomy and protection against ulcerative colitis显示文摘 | Anderson RE Olaison G Tysk C | 2001 | N Engl J Med2001，344，11： | 1 |
| 17 | Colonic perforation in collagenous colitis: an unusual complication显示文摘 | Johan Bohr Lars-G?ran Larsson Sune Eriksson Gunnar J?rnerot Curt Tysk | 2005 | European Journal of Gastroenterology & Hepatology2005，，1： | 1 |
| 18 | Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins:a study of heritability and the influence of smoking 显示文摘 | TYSK C LINDBERG E JARNEROT G | 1988 | Gut1988，29，： | 1 |
| 19 | Appendectomy is followed by increased risk of Crohn’s disease显示文摘 | Roland E. Andersson Gunnar Olaison Curt Tysk Anders Ekbom | 2003 | Gastroenterology2003，，1： | 1 |
| 20 | Smoking and inflammatory bowel disease:a case control study显示文摘 | Tysk C Andersson K | 1988 | Gut1988，29，： | 1 |
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