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| 1 | Main controversies in breast cancer显示文摘In this article, we have reviewed available evidence for diagnosis, treatment, and follow-up in female breast cancer(BC). Into daily clinical practice some controversies are occurred. Especially, in the diagnosis field, despite the fact that the optimal age in which screening mammography should start is a subject of intense controversy, there is a shift toward the beginning at the age of 40 although it is suggested that the net benefit is small for women aged 40 to 49 years. In addition, a promising tool in BC screening seems to be breast tomosynthesis. Other tools such as 3D ultrasound and shear wave elastography(SWE) are full of optimism in BC screening although ultrasonography is not yet a first-line screening method and there is insufficient evidence to recommend the systemic use of the SWE for BC screening. As for breast magnetic resonance imaging(MRI), even if it is useful in BC detection in women who have a strong family history of BC, it is not generally recommended as a screening tool. Moreover, based on the lack of randomized clinical trials showing a benefit of presurgical breast MRI in overall survival, it's integration into breast surgical operations remainsdebatable. Interestingly, in contrast to fine needle aspiration, core biopsy has gained popularity in presurgical diagnosis. Furthermore, after conservative surgery in patients with positive sentinel lymph nodes, the recent tendency is the shift from axillary dissection to axillary conserving strategies. While the accuracy of sentinel lymph node after neoadjuvant chemotherapy and second BC surgery remains controversial, more time is needed for evaluation and for determining the optimal interval between the two surgeries. Additionally, in the decision between immediate or delayed breast reconstruction, there is a tendency in the immediate use. In the prevention of BC, the controversial issue between tamoxifen and raloxifene becomes clear with raloxifene be more profitable through the toxicities of tamoxifen. However, the prevention of bone metastasis with bisphosphonates is still conflicting. Last but not least, in the follow-up of BC survivors, mammography, history and physical examination are the means of an early detection of BC recurrence. | Stephane Zervoudis George Iatrakis Eirini Tomara Anastasia Bothou George Papadopoulos George Tsakiris | 2014 | World Journal of Clinical Oncology2014，5，3： | 5 |
| 2 | Enhanced recovery after surgery in liver transplantation:Challenges and feasibility显示文摘BACKGROUND Enhanced recovery after surgery(ERAS)started a revolution that changed age-old surgical stereotypical practices regarding the overall management of the surgical patient.In the last decade,ERAS has gained significant acceptance in the community of general surgery,in addition to several other surgical specialties,as the evidence of its advantages continues to grow.One of the last remaining fields,given its significant complexity and intricate nature,is liver transplantation(LT).AIM To investigate the existing efforts at implementing ERAS in LT.METHODS We conducted a systematic review of the existing studies that evaluate ERAS in orthotopic LT,with a multimodal approach and focusing on measurable clinical primary endpoints,namely length of hospital stay.RESULTS All studies demonstrated a considerable decrease in length of hospital stay,with no readmission or negative impact of the ERAS protocol applied to the postoperative course.CONCLUSIONS ERAS is a well-validated multimodal approach for almost all types of surgical procedures,and its future in selected LT patients seems promising,as the preliminary results advocate for the safety and efficacy of ERAS in the field of LT. | Georgios Katsanos Konstantina-Eleni Karakasi Nikolaos Antoniadis Stella Vasileiadou Athanasios Kofinas Antonios Morsi-Yeroyannis Evangelia Michailidou Ioannis Goulis Emmanouil Sinakos Olga Giouleme Ilias Marios Oikonomou George Evlavis Georgios Tsakiris Eleni Massa Eleni Mouloudi Georgios Tsoulfas | 2022 | World Journal of Transplantation2022，12，7： | 3 |
| 3 | Regional Drought Assessment Based on the Reconnaissance Drought Index (RDI)显示文摘 | G. Tsakiris D. Pangalou H. Vangelis | 2007 | Water Resources Management2007，，5： | 2 |
| 4 | Supersonic radiative heat waves in low density high Z material显示文摘 | Massen J Tsakiris G D Eidmann K | 1994 | Phys Rev E1994，50，6： | 1 |
| 5 | Beneficial effects of switchin8 from beta-blockers to nebivolol on the erectile function of hypertensive patients显示文摘 | Doumas M Tsakiris A Douma S | 2006 | Asian J Androl2006，8，2： | 1 |
| 6 | The evolution of KTP laser vaporization of the prostate显示文摘 | Sountoulides P Tsakiris P | | 0，，02： | 1 |
| 7 | Size and motion of the mitral valve annulus in anesthetized intact dogs 显示文摘 | von Bemuth G Rastelli GS | 1971 | J Appl Physiol1971，30，： | 1 |
| 8 | Regional drought assessment based on the reconnaissance drought index 显示文摘 | TSAKIRIS G PANGALOU D VANGELIS H | 2007 | Water Resour Manage2007，21，： | 1 |
| 9 | ADH levels following nonhypotensive hemorrhage in dogs with chronic mireal stenosis显示文摘 | Zehr J E Hawe A Tsakiris A G | 1971 | Am J Physiol1971，221，1： | 1 |
| 10 | Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurones 显示文摘 | Tsakiri N Kimber I Rothwell NJ | 2008 | Mol Cell Neurosci2008，38，2： | 1 |
| 11 | Platelets and cytokines in concert with endothelial activation in patients with peripheral arterial occlusive disease显示文摘 | Tsakiris DA Tschopl M Wolf F | 2000 | Blood coag Fibrinol2000，11，： | 1 |
| 12 | Beneficial effects of switching from beta-blockers to nebivolol on the erectile function of hypertensive patients 显示文摘 | Doumas M Tsakiris A Douma S | 2006 | Asian J Androl2006，8，2： | 1 |
| 13 | On regional drought estimation and analysis 显示文摘 | RossiG Benedini M Tsakiris G | 1992 | Water Resources Manage- ment1992，6，： | 1 |
| 14 | A discrimination test procedure for ambiguity resolution on-the-fly显示文摘 | Wang J Stewart MP & Tsakiri M | 1998 | Journal of Geodesy1998，72，： | 1 |
| 15 | The role of motor intention in motor awareness:an experimental study on anosognosia for hemiplegia显示文摘 | Aikaterini Fotopoulou Manos Tsakiris Patrick Haggard | 2008 | Brain2008，131，： | 1 |
| 16 | Proteasome dysfunction in Drosophila signals to an Nrf2 dependent regulatory circuit aiming to restore proteostasis and prevent premature aging显示文摘 | Tsakiri E N Sykiotis G P Papassideri I S | 2013 | Aging cell2013，12，5： | 1 |
| 17 | Haemostatic profile in hypothyroidism as potential risk factor for vascular or thrombotic disease显示文摘 | Muller B Tsakiris DA Roth CB | 2001 | Eur J Clin Invest2001，31，2： | 1 |
| 18 | A method for applying crop sensitivity factors in irrigation scheduling显示文摘 | G P Tsakiris | 1982 | Agric Water Management1982，，5： | 1 |
| 19 | Prognostic factors and percutaneous nephrolithotomy morbidity: a multi- variate analysis of a contemporary series using the Clavien classification显示文摘 | de la Rosette J J Zuazu J R Tsakiris P | 2008 | J Urol2008，180，6： | 1 |
| 20 | Beyond prone position in percutaneous nephrolithotomy:a comprehensive review显示文摘 | de la Rosette JJ Tsakiris P Ferrandino MN | 2008 | Eur Urol2008，54，6： | 1 |
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