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| 1 | Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation显示文摘BACKGROUND Pre-transplant nutrition is a key driver of outcomes following liver transplantation in children.Patients with biliary atresia(BA) may have difficulty achieving satisfactory weight gain with enteral nutrition alone,and parenteral nutrition(PN) may be indicated.While PN has been shown to improve anthropometric parameters of children with BA listed for liver transplantation,less is known about the risks,particularly infectious,associated with this therapy among this specific group of patients.AIM To describe the incidence,microbiology,and risk factors of central line-associated bloodstream infection(CLABSI) among children with BA listed for liver transplantation.METHODS Retrospective review of children aged ≤ 2-years of age with BA who were listed for primary liver transplantation at Texas Children's Hospital from 2008 through2015(n = 96).Patients with a central line for administration of PN(n = 63) were identified and details of each CLABSI event were abstracted.We compared the group of patients who experienced CLABSI to the group who did not,to determine whether demographic,clinical,or laboratory factors correlated with development of CLABSI.RESULTS Nineteen of 63 patients(30%,95%CI:19,43) experienced 29 episodes of CLABSI during 4800 line days(6.04 CLABSI per 1000 line days).CLABSI was predominantly associated with Gram-negative organisms(14/29 episodes,48%)including Klebsiella spp.,Enterobacter spp.,and Escherichia coli.The sole polymicrobial infection grew Enterobacter cloacae and Klebsiella pneumoniae.Grampositive organisms(all Staphylococcus spp.) and fungus(all Candida spp.)comprised 9/29(31%) and 6/29(21%) episodes,respectively.No demographic,clinical,or laboratory factors were significantly associated with an increased risk for the first CLABSI event in Cox proportional hazards regression analysis CONCLUSION There is substantial risk for CLABSI among children with BA listed for liver transplantation.No clinical,demographic,or laboratory factor we tested emerged as an independent predictor of CLABSI.While our data did not show an impact of CLABSI on the short-term clinical outcome,it would seem prudent to implement CLABSI reduction strategies in this population to the extent that each CLABSI event represents potentially preventable hospitalization,unnecessary healthcare dollar expenditures,and may exact an opportunity cost,in terms of missed allograft offers. | Nicole D Triggs Stacey Beer Sonam Mokha Kat Hosek Danielle Guffey Charles G Minard Flor M Munoz Ryan W Himes | 2019 | World Journal of Hepatology2019，11，2： | 2 |
| 2 | Corrosion of selected nonoxide ceramics in liquid steel显示文摘 | Trigg M B Ellson D B Sinclair W | 1988 | Br Ceram Trans1988，87，： | 1 |
| 3 | Chediak-Higashi syndrome, hematopoietic chimerism corrects genetic defect显示文摘 | Trigg M Schugar R | 2001 | Bone Marrow Transplantation2001，27，11： | 1 |
| 4 | Time of Day Variations in Driving Performance显示文摘 | Lenne M G Triggs T J Redman J R | 1997 | Accident Analysis and Prevention1997，29，4： | 1 |
| 5 | Influence of pigment composition on skin color in a wide range of fruit and vegetables显示文摘 | LANCASTER J E LISTER C E REAY P F TRIGGS C M | 1997 | J Amer Soc Hort Sci1997，122，4： | 1 |
| 6 | Sampling factors affecting the use of mineral analysis of apple fruit for prediction of bitter pit显示文摘 | FERGUSON I B TRIGGS C M | 1990 | New Zealand J Crop Hortic Sci1990，18，： | 1 |
| 7 | Repetitive transcranial magnetic stimulation of motor cortex after stroke: a focused review 显示文摘 | Corti M Patten C Triggs W | 2012 | Am J Phys Med Rehabil2012，91，3： | 1 |
| 8 | Repetitive Transcranial Magnetic Stimulation of Motor Cortex after Stroke: A Focused Review显示文摘 | Corti M Patten C Triggs W | 2012 | Am J Phys Med Rehabil2012，91，3： | 1 |
| 9 | Free-air CO2 enrichment effects on the energy balonce and evapotranspiration of sorghum显示文摘 | TRIGGS J M KIMBALL B A PINTER P J | 2004 | Agriaultural and Forest Meteorology2004，124，： | 1 |
| 10 | Relationships within the proteobacteria of plant pathogenic acidovorax species and subspecies,Burkholderia species,and herbaspirillum rubrisubalbicans by sequence analysis of 16S rDNA,numerical analysis and determinative tests显示文摘 | HU F P YOUNG J M TRIGGS C M | 2001 | Antonie Van Leeuwenhoek2001，80，34： | 1 |
| 11 | The Fabrication of O'-Sialon Ceramics by Pressureless Sintering显示文摘 | M B Trigg K H Jack | 1988 | J of MaterialsScience1988，23，： | 1 |
| 12 | Sustained testicular atrophy in bulls actively immunized against GnRH: potential to control carcase characteristics 显示文摘 | DOeehio M J Aspden W J Trigg T E | 2001 | Anim Reprod Sci2001，66，12： | 1 |
| 13 | Parallelisation of storage cell flood models using OpenMP 显示文摘 | Neal J C Fewtrell T J Trigg M | 2009 | Environmental Modelling & Software2009，24，7： | 1 |
| 14 | Repetitive transcranial magnet-ic stimulation of motor cortex after stroke: a focused review显示文摘 | CORTI M PATTEN C TRIGGS W | 2012 | Am J Phys Med Rehabil2012，91，： | 1 |
| 15 | The adsorption of heterocyclic aromatic amines by model dietary fibres with contrasting ompositions显示文摘 | Philip J Harris Christopher M Triggs Anthony M Roberton | 1996 | Chemico-Biological Interactions1996，，100： | 1 |
| 16 | Repetitive transcranial magnetic stimulation of mo- tor after stroke: a focused review 显示文摘 | Corti M Triggs W | 2012 | Am J Phys Med Rehabil2012，91，3： | 1 |
| 17 | Repetitive transcranial magnetic stimulation of motor cortex after stroke: a focused review显示文摘 | Corti M Patten C Triggs W | 2012 | Am JPhysMedRehabil2012，91，3： | 1 |
| 18 | Apple firmness: creating a tool for product evaluation based on a sensory-instrumental relationship显示文摘 | HARKER F R GUNSONA F A TRIGGS C M | 2006 | Postharvest Biology and Technology2006，39，3： | 1 |
| 19 | Repetitive transcranial mag- netic stimulation of motor cortex after stroke: a focused re- view显示文摘 | Corti M Patten C Triggs W | 2012 | Am J Phys Med Rehahil2012，91，3： | 1 |
| 20 | Evaluation of the E2L toy test as a sereening proeedure in elinieal praetiee显示文摘 | Bellman S Mahon M Triggs E | 1996 | Br J Audiol1996，30，： | 1 |
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