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| 1 | Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation显示文摘BACKGROUND Pre-transplant nutrition is a key driver of outcomes following liver transplantation in children.Patients with biliary atresia(BA) may have difficulty achieving satisfactory weight gain with enteral nutrition alone,and parenteral nutrition(PN) may be indicated.While PN has been shown to improve anthropometric parameters of children with BA listed for liver transplantation,less is known about the risks,particularly infectious,associated with this therapy among this specific group of patients.AIM To describe the incidence,microbiology,and risk factors of central line-associated bloodstream infection(CLABSI) among children with BA listed for liver transplantation.METHODS Retrospective review of children aged ≤ 2-years of age with BA who were listed for primary liver transplantation at Texas Children's Hospital from 2008 through2015(n = 96).Patients with a central line for administration of PN(n = 63) were identified and details of each CLABSI event were abstracted.We compared the group of patients who experienced CLABSI to the group who did not,to determine whether demographic,clinical,or laboratory factors correlated with development of CLABSI.RESULTS Nineteen of 63 patients(30%,95%CI:19,43) experienced 29 episodes of CLABSI during 4800 line days(6.04 CLABSI per 1000 line days).CLABSI was predominantly associated with Gram-negative organisms(14/29 episodes,48%)including Klebsiella spp.,Enterobacter spp.,and Escherichia coli.The sole polymicrobial infection grew Enterobacter cloacae and Klebsiella pneumoniae.Grampositive organisms(all Staphylococcus spp.) and fungus(all Candida spp.)comprised 9/29(31%) and 6/29(21%) episodes,respectively.No demographic,clinical,or laboratory factors were significantly associated with an increased risk for the first CLABSI event in Cox proportional hazards regression analysis CONCLUSION There is substantial risk for CLABSI among children with BA listed for liver transplantation.No clinical,demographic,or laboratory factor we tested emerged as an independent predictor of CLABSI.While our data did not show an impact of CLABSI on the short-term clinical outcome,it would seem prudent to implement CLABSI reduction strategies in this population to the extent that each CLABSI event represents potentially preventable hospitalization,unnecessary healthcare dollar expenditures,and may exact an opportunity cost,in terms of missed allograft offers. | Nicole D Triggs Stacey Beer Sonam Mokha Kat Hosek Danielle Guffey Charles G Minard Flor M Munoz Ryan W Himes | 2019 | World Journal of Hepatology2019，11，2： | 2 |
| 2 | Quantitative cytology of ganglion neurons and satellite glial cells in the superior cervical ganglion of the sheep:relationship with ganglion neuron size显示文摘 | Gabella G Trigg P McPhail H | 1988 | Neurocytol1988，17，6： | 1 |
| 3 | Corrosion of selected nonoxide ceramics in liquid steel显示文摘 | Trigg M B Ellson D B Sinclair W | 1988 | Br Ceram Trans1988，87，： | 1 |
| 4 | Enhanced Local Texture Feature Sets for Face Recognition Under Difficult Lighting Conditions显示文摘 | Tan X Triggs B | 2010 | IEEE Transactions on Image Processing2010，19，6： | 1 |
| 5 | Enhanced local texture feature sets for face recognition under difficult lighting conditions 显示文摘 | Tan X Triggs B | 2010 | IEEE Transactions on Image Processing2010，19，6： | 1 |
| 6 | Use of coronary Palmaz-Sehatz stent in the pereutaneous treatment of an intracranial carotid artery stenosis显示文摘 | Feldman RL Trigg L Gaudier J | 1996 | Cathet Cardiovasc Diagn1996，38，3： | 1 |
| 7 | Transplantation of HLA-haploidentical T-cell-depleted marrow for leukemia:addition of cytosine arabinoside to the pretransplant conditioning prevents rejection显示文摘 | Bozdech MJ Sondel PM Trigg ME | 1985 | Exp Hematol1985，13，11： | 1 |
| 8 | Chediak-Higashi syndrome, hematopoietic chimerism corrects genetic defect显示文摘 | Trigg M Schugar R | 2001 | Bone Marrow Transplantation2001，27，11： | 1 |
| 9 | Genetic map- ping of KatG,a locus that affects synthesis of the bifunc tional catalase peroxidase hydroperoxidase I in Esche richia coli 显示文摘 | Loewen P C Triggs B L George C S | 1985 | Journal of Bacteriology1985，162，2： | 1 |
| 10 | The robustness of a continuous likelihood approach to bayesian analysis of forensic glass evidence显示文摘 | Curran J.M Buckletonb J Triggs C.M | | 0，，02： | 1 |
| 11 | Enhanced local texture feature sets for face recognition under difficult lighting conditions 显示文摘 | TAN X TRIGGS B | 2010 | IEEE Transac- tions on Image Processing2010，19，6： | 1 |
| 12 | From transaction to transformation: Infor- mation and communication technology, professional devel- opment and the formation of communities of practice 显示文摘 | Triggs P John P | 2004 | Journal of Computer Assisted Learning2004，，20： | 1 |
| 13 | A novel diuretic hormone receptor in Drosophila:evidence for conservation of CGRP signaling 显示文摘 | Johnson E C Shafer O T Trigg J S | 2005 | J Exp Biol2005，208，7： | 1 |
| 14 | Enhanced Local Texture Feature Sets for Face Recognition Under Difficult Lighting Conditions显示文摘 | Tan X Y Triggs B | | 0，，06： | 1 |
| 15 | Enhanced local texture feature sets for face recognition under difficult lighting conditions 显示文摘 | TAN X TRIGGS B | 2010 | IEEE Transactions on Image Processing2010，19，6： | 1 |
| 16 | Detection of MicroRNAs using target-guided formation of conducting polymer nanowires in nanogaps 显示文摘 | Fan Y Chen X Trigg A D | 2007 | J Am Chem Soc2007，129，17： | 1 |
| 17 | Incorporatin of radioactive precur-sors into DNA and RNA of Plasmodium knowlesi in vitro显示文摘 | Gutteridge W E Trigg P I | | 0，，01： | 1 |
| 18 | Time of Day Variations in Driving Performance显示文摘 | Lenne M G Triggs T J Redman J R | 1997 | Accident Analysis and Prevention1997，29，4： | 1 |
| 19 | Enhanced local texture feature sets for face recognition under difficult lighting conditions 显示文摘 | Xiao yang Tan B Triggs | 2010 | Image Processing IEEE Transactions on2010，19，6： | 1 |
| 20 | Influence of pigment composition on skin color in a wide range of fruit and vegetables显示文摘 | LANCASTER J E LISTER C E REAY P F TRIGGS C M | 1997 | J Amer Soc Hort Sci1997，122，4： | 1 |
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