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| 1 | On the cell biology of pit cells,the liver-specific NK cells显示文摘INTRODUCTION Natural killer (NK) cells are functionally defined by their ability to kill certain tumor cells and virus-infected cells without prior | Luo DZ Vermijlen D Ahishali B Triantis V Plakoutsi G Braet F Vanderkerken K Wisse E | 2000 | World Journal of Gastroenterology2000，6，1： | 8 |
| 2 | Participation of CD45,NKR-P1A and ANK61 antigen in rat hepatic NK cell(pit cell)-mediated target cell cytotoxicity显示文摘AIM Several triggering receptors have beendescribed to be involved in natural killer(NK)cell-mediated target cytotoxicity.In these studies,NKcells derived from blood or spleen were used.Pitcells are liver-specific NK cells that possess ahigher level of natural cytotoxicity and a differentmorphology when compared to blood NK cells.The aim of this study was to characterize the roleof the NK-triggering molecules NKR-P1A,ANK61antigen,and CD45 in pit cell-mediated killing oftarget cells.METHODS 51Cr-release and DNA fragmentationwere used to quantify target cell lysis andapoptosis,respectively.RESULTS Flow cytometric analysis showed thatpit cells expressed CD45,NKR-P1A,and ANK61antigen.Treatment of pit cells with monoclonalantibody(mAb)to CD45(ANK74)not onlyinhibited CC531s or YAC-1 target lysis but alsoapoptosis induced by pit cells.The mAbs to NKR-P1A(3.2.3)and ANK61 antigen(ANK61)had no effect on pit cell-mediated CC531s or YAC-1 targetcytolysis or apoptosis,while they did increase theFcγ receptor positive(FcγR+)P815 cytolysis andapoptosis.This enhanced cytotoxicity could beinhibited by 3,4-dichloroisocoumarin,an inhibitorof granzymes.CONCLUSION These results indicate that CD45participates in pit cell-mediated CC531s and YAC-1target cytolysis and apoptosis.NKR-P1A andANK61 antigen on pit cells function as activationstructures against FcγR+ P815 cells,which wasmediated by the perforin/granzyme pathway. | David Vermiilen Bülent Ahishali Vasilis Triantis Karin Vanderkerken Peter J. K.Kuppen Eddie Wisse | 2000 | World Journal of Gastroenterology2000，6，4： | 4 |
| 3 | Why do firms go dark? Causes and economic consequences of voluntary SEC deregistrations显示文摘 | Christian Leuz Alexander Triantis Tracy Yue Wang | 2008 | Journal of Accounting and Economics2008，，2： | 2 |
| 4 | The Value of Financial Flexibility显示文摘 | ANDREA GAMBA ALEXANDER TRIANTIS | 2008 | The Journal of Finance2008，，5： | 2 |
| 5 | Dynamic R&D investment poli- cies 显示文摘 | Childs P D Triantis A J | 1999 | Management Science1999，45，10： | 1 |
| 6 | Photoeatalytic reduetive-oxidative degradation of Acid Orange 7 by polyoxometal/ate 显示文摘 | TROUPIS A TRIANTIS T M GKIKA E | 2009 | Applied Catalysis B : Environmental2009，86，： | 1 |
| 7 | Photocatalysis by polyoxometallates and TiO2:A comparative study显示文摘 | Kormali P Troupis A Triantis T | 2007 | Catal Today2007，124，： | 1 |
| 8 | The Value of Financial Flexibili- ty显示文摘 | Gamba A Triantis A | 2008 | Journal of Finance2008，63，05： | 1 |
| 9 | Assessing Aggregate Cost Efficiency and the Related Policy Implications for Greek Local Municipalities显示文摘 | Athanassopoulos A Triantis K | 1998 | INFOR1998，36，3： | 1 |
| 10 | Valuing flexibility: An impulse control framework显示文摘 | Hodder J E and A J Triantis | 1992 | Annals of Operations Research1992，45，： | 1 |
| 11 | A neural network approach for compressive strength prediction in cement-based materials through the study of pressure-stimulated electrical signals显示文摘 | Alexandridis A Triantis D Stavrakas I | 2012 | Construction and Building Materials2012，，30： | 1 |
| 12 | Perfbrmance evaluation of bus routes:a provider and passenger perspective 显示文摘 | SHETH C TRIANTIS K TEODOROVIC D | 2007 | Transporta- tion Research Part E: Logistics and Transportation Review2007，43，4： | 1 |
| 13 | The Value of Financial Flexibility显示文摘 | Andrea Gamba Alexander Triantis | 2008 | The Journal of Finance2008，63，5： | 1 |
| 14 | Performance measurement of a transportation network with a downtown space reservation system: A network-DEA approach显示文摘 | Zhao Y Triantis K Murray-Tuite P | 2011 | Transportation Research Part E2011，47，11： | 1 |
| 15 | Assessing Ag gregate Cost Efficiency and the Related Policy Implications for Greek Local Municipalities显示文摘 | Antreas Athanassopoulos Konstantino Triantis | 1998 | INFOR1998，36，3： | 1 |
| 16 | Dynamic R&D investment policies显示文摘 | Childs P D Triantis A J | 1999 | Management Science1999，45，10： | 1 |
| 17 | Chemiluminescent studies on the antioxidant activity of amino acids显示文摘 | T.M. Triantis E. Yannakopoulou A. Nikokavoura D. Dimotikali K. Papadopoulos | 2007 | Analytica Chimica Acta2007，，1： | 1 |
| 18 | The Value of Financial Flexibility 显示文摘 | Gamba A Triantis A | 2008 | The Journal of Finance2008，63，5： | 1 |
| 19 | Mixed uses and the redevelopment option显示文摘 | Childs P Riddioagh T Triantis A | 1996 | Real Estate Economics1996，24，3： | 1 |
| 20 | Performance evaluation ofbus routes: A provider and passenger perspective 显示文摘 | ShethC Triantis K Teodorovic D | 2007 | Trans-portation Research2007，43，4： | 1 |
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