|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Influence of hepatitis viruses on clinico-pathological profiles and long-term outcome in patients undergoing surgery for hepatocellular carcinoma显示文摘BACKGROUND: The global risk of hepatocellular carcinoma(HCC) is largely due to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. In recent years, however, an increased prevalence of non-viral HCC has been noted. The clinical impact of the presence/absence of viral infections in HCC remains controversial. The present study aimed to assess the effect of hepatitis viruses on demographics, clinical and pathological features and long-term outcome in a large cohort of Romanian patients who underwent surgery for HCC. METHODS: The study included 404 patients with HCC who had undergone resection, transplantation or radiofrequency ablation at a single institution between 2001 and 2010. The patients were divided into four groups: 85 patients with hepatitis B virus infection (HBV group), 164 patients with hepatitis C virus infection (HCV group), 39 patients with hepatitis B and C virus co-infection (HBCV group), and 116 patients without viral infection (non-BC group). RESULTS: The patients of both HBV (56.0±11.3 years) and HBCV groups (56.0±9.9 years) were significantly younger than those of the HCV (61.0±8.5 years, P=0.001) and non-BC groups(61.0±13.0 years, P=0.002). Interestingly, the prevalence of liver cirrhosis was significantly lower in the non-BC group (47%)than in any other subsets (72%-90%, P<0.002). Furthermore, the non-BC patients were more advanced according to the Barcelona Clinic Liver Cancer stages than the patients of the HCV or HBCV groups (P<0.020); accordingly, they were more frequently assessed beyond the Milan criteria than any other groups (P=0.001). No significant differences in the disease-free or overall survival rates were observed among these groups. CONCLUSIONS: Patients with non-viral HCC are diagnosed at advanced ages and stages, a situation plausibly due to the poor effectiveness of cancer surveillance in community practice. The presence of viral infections does not appear to impair the longterm prognosis after surgical treatment in patients with HCC; however, there is a trend for worse disease-free survival rates in HBCV patients, though statistical significance was not reached. | Anna-Maria Tanase Traian Dumitrascu Simona Dima Razvan Grigorie Agnes Marchio Pascal Pineau Irinel Popescu | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，2： | 7 |
| 2 | 氟碳介质热致气液两相流的工频击穿特性及其在GIL中的应用展望显示文摘目前已有一些环保型氟碳介质可替代SF_6气体应用于变压器、GIS甚至GIL中,其在工作中以液态或气液两相态的形式存在。但是,液态绝缘介质在受热状态下的气液两相流的绝缘特性和放电机理尚未明晰。文中采用自发热电极进行了氟碳介质热致气液两相流随热流密度、工作压力等热力学参数的工频击穿电压测量实验,结果表明:其击穿电压随热流密度呈'Z'字型的曲线规律变化;击穿电压突变点与表面过热度的极值点高度相符,以此提出了表征击穿电压突变的特征值和特征向量。最后,通过仿真分析和计算初步证明,环保型氟碳介质在绝缘和冷却两个方面完全具有替代SF_6气体应用于环保介质绝缘管道电缆的可行性。 | 牛文豪 张国强 林涛 李康 Adrian Traian Plesca | 2017 | 高电压技术2017，43，3： | 5 |
| 3 | Multimodality treatment strategies have changed prognosis of peritoneal metastases显示文摘For a long time, treatment of peritoneal metastases(PM) was mostly palliative and thus, this status was link with 'terminal status/despair'. The current multimodal treatment strategy, consisting of cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC), has been strenuously achieved over time, but seems to be the best treatment option for PM patients. As we reviewed the literature data, we could emphasize some milestones and also, controversies in the history of proposed multimodal treatment and thus, outline the philosophy of this approach, which seems to be an unusual one indeed. Initially marked by nihilism and fear, but benefiting from a remarkable joint effort of human and material resources(multi-center and-institutional research), over a period of 30 years, CRS and HIPEC found their place in the treatment of PM. The next 4 years were dedicated to the refinement of the multimodal treatment, by launching research pathways. In selected patients, with requires training, it demonstrated a significant survival results(similar to the Hepatic Metastases treatment), with acceptable risks and costs. The main debates regarding CRS and HIPEC treatment were based on the oncologists' perspective and the small number of randomized clinical trials. It is important to statement the PM patient has the right to be informed of the existence of CRS and HIPEC, as a real treatment resource, the decision being made by multidisciplinary teams. | corneliu lungoci aurel ion mironiuc valentin muntean traian oniu hubert leebmann max mayr pompiliu piso | 2016 | World Journal of Gastrointestinal Oncology2016，8，1： | 2 |
| 4 | Synthesis of styrene-acrylonitrile copolymers and related block copolymers by atom transfer radical polymerization显示文摘 | Nicolay V Tsarevsky Traian Sarbu Bernd Gol belt | 2002 | Macromolecules2002，35，16： | 1 |
| 5 | Specificity determinants of human eathepsin S revealed by crystal structures of complexes 显示文摘 | Thomas AP Traian S Mark A | 2003 | Biochemistry2003，42，11： | 1 |
| 6 | Effects of Aqueous Al, Cd, Cu, Fe(Ⅱ),NiandZnon Pbimmobilization by Hydroxyapatite 显示文摘 | MaQY TraianS J LoganTJ | 1994 | Environ Sci Technol1994，28，7： | 1 |
| 7 | New line arresters aim to improve reliability of key Romanian transmission line显示文摘 | Stelian Alexandru Gal Traian Fagarasan Marius Ohean | 2006 | Insulator News and Market Report (INMR)2006，14，2： | 1 |
| 8 | High chromosome instability and occasional R249S TP53 Mutation characterize hepatocellular carcinoma in Romania显示文摘 | Agnès Marchio Anna-Maria Tanase Traian Dumitrascu Mariana Mihaila Simona Dima Anne Dejean Irine Popescu Gabriela Oprisan Pascal Pineau | 2010 | Cancer Genetics and Cytogenetics2010，，1： | 1 |
| 9 | Timing analysis of the FlexRay communication protocol显示文摘 | Traian Pop Paul Pop Petru Eles | 2008 | Real-Time Systems2008，39，8： | 1 |
| 10 | Petru budrugeac,radiation processing of EPDM/PP blends,thermal effect of low dose irradiation显示文摘 | Traian Zaharescu | 2002 | Polymer Bulletin2002，49，： | 1 |
| 11 | Multi-stock portfolio optimization under prospect theory显示文摘 | Traian Pirvu Klaas Schulze | 2012 | Mathematics and Financial Economics2012，，4： | 1 |
| 12 | Metal Ion Release With Large-Diameter Metal-on-Metal Hip Arthroplasty显示文摘 | Pascal-André Vendittoli Traian Amzica Alain G. Roy Daniel Lusignan Julien Girard Martin Lavigne | 2011 | The Journal of Arthroplasty2011，，2： | 1 |
| 13 | Resection for Hilar Cholangiocarcinoma: Analysis of Prognostic Factors and the Impact of Systemic Inflammation on Long-term Outcome显示文摘 | Traian Dumitrascu Dragos Chirita Mihnea Ionescu Irinel Popescu | 2013 | Journal of Gastrointestinal Surgery2013，，： | 1 |
| 14 | Field performance and biomass production of 12 willow and poplar clones in short-rotation coppice in southem Quebec (Canada) 显示文摘 | Michel Labrecque Traian I Teodorescu | 2005 | Biomass and Bioenergy2005，29，7： | 1 |
| 15 | An overview of the development of artificial corneas with porous skirts and the use of PHEMA for such an application显示文摘 | TRAIAN V CHIRILA | 2001 | Biomaterials2001，22，24： | 1 |
| 16 | Integrated genetic algorithm and goal programming for network topology design problem with multiple objectives and multiple criteria显示文摘 | Laurent B Traian M | | 0，，03： | 1 |
| 17 | Synthesis, physical characterization, and biological performance of sequential homointerpenetrating polymer network sponges based on poly (2-hydroxyethyl methaerylate) 显示文摘 | XIA L SAROJINI V TRAIAN V | 1999 | J Biomed Mater Res1999，47，3： | 1 |
| 18 | Investment and consumption without commitment 显示文摘 | Ivar Ekeland Traian A Pirvu | 2008 | Mathematics and Financial Economics2008，2，1： | 1 |
| 19 | Screening for drug-induced spoliation of the hydrogel optic of the AlphaCor^TM artificial coruea显示文摘 | DAVID A ZOYA G TRAIAN V | 2006 | Contact Lens & Anterior Eye2006，29，2： | 1 |
| 20 | A dynamic model for the impact between the wheel flat and rail, UPB scientific bulletin, series D显示文摘 | TRAIAN M | 2007 | Mechanical Engineering2007，69，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员