|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2015年全球新药研发报告——第二部分:趋势复杂,亮点频现(Ⅴ)显示文摘概述并精辟解析2015年全球制药行业发生的重大事件,包括药品定价、孤儿药研发、美国FDA优先审评凭证制度、药品研发管线缩减以及正在持续运作的并购。并展望未来,预测2016年有望上市的新药。 | Graul A I Cruces E Dulsat C Tracy M | 2016 | 药学进展2016，40，8： | 2 |
| 2 | Reduced striatal volumes in Parkinson’s disease:a magnetic resonance imaging study显示文摘Background:The presence and extent of structural changes in the brain as a consequence of Parkinson’s disease(PD)is still poorly understood.Methods:High-resolution 3-tesla T1-weighted structural magnetic resonance images in sixty-five PD and 27 age-matched healthy control participants were examined.Putamen,caudate,and intracranial volumes were manually traced in the axial plane of 3D reconstructed images.Striatal nuclei volumes were normalized to intracranial volume for statistical comparison.Disease status was assessed using the Unified Parkinson’s Disease Rating Scale and Hoehn and Yahr scale.Cognitive status was assessed using global status tests and detailed neuropsychological testing.Results:Both caudate and putamen volumes were smaller in PD brains compared to controls after adjusting for age and gender.Caudate volumes were reduced by 11%(p=0.001)and putamen volumes by 8.1%(p=0.025).PD striatal volumes were not found to be significantly correlated with cognitive or motor decline.Conclusion:Small,but significant reductions in the volume of both the caudate and putamen occur in PD brains.These reductions are independent of the effects of age and gender,however the relation of these reductions to the functional loss of dopamine,which is characteristic of PD,remains unclear. | Toni L Pitcher Tracy R Melzer Michael R MacAskill Charlotte F Graham Leslie Livingston Ross J Keenan Richard Watts John C Dalrymple-Alford Tim J Anderson | 2012 | Translational Neurodegeneration2012，1，1： | 2 |
| 3 | Lp(a) lipoprotein,vascular disease and mortality in the elderly显示文摘 | Ariyo AA Thach C Tracy R | 2003 | N Engl JMed2003，349，22： | 1 |
| 4 | Application of ultra- high moulus composites to primary structures 显示文摘 | Foster J L Tracy J J Elizondo C A | 1993 | AIAA-93-1405 -CP1993，，： | 1 |
| 5 | Z01Z ACCP/AFIA/ HRS Focused Update of the 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities A Report of the Ameri- can College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines显示文摘 | Tracy C M Epstein A E Darbar D | 2012 | Circulation2012，126，14： | 1 |
| 6 | Characteristics associated with longer breast显示文摘 | Tracie AB Tan C Patricia AB | 2009 | J Hum Lact2009，25，1： | 1 |
| 7 | Chromic mechanism in amorphous WO3films显示文摘 | Zhang J G Benson D K Tracy C E | 1997 | Electrochem Soc1997，144，： | 1 |
| 8 | Preparation of monodisperse silica particales: Control of size and mass fraction显示文摘 | Bogush G H Tracy M A Zukoskin C F | 1988 | J Non-Cryst Solids1988，104，： | 1 |
| 9 | Peer-to-peer Lending to Small Businesses显示文摘 | Traci L M Courtney M C Cailin R S | 2014 | Staff Working Pa- pers in the Finance and Economics Discussion Se- ries2014，10，： | 1 |
| 10 | Chromic mechanism in amorphous WO3 films 显示文摘 | ZHANG J BENSON D TRACY C | 1997 | Journal of the Electrochemi- cal Society1997，144，6： | 1 |
| 11 | Service Quality Attribute Weights: How Do Novice and Longer- Term Customers Construct ServiceQuality Perceptions? 显示文摘 | Tracy S D Sweeney J C | 2007 | Journal of Service Research2007，10，2： | 1 |
| 12 | On orthogonal and symplecticmatrix ensembles 显示文摘 | TRACY C A WIDOM H | 1996 | Communications in MathematicalPhysics1996，177，3： | 1 |
| 13 | Outcomes of mandible fracturetreatment at an academic tertiary hospital: a 5-year analysis 显示文摘 | Gutta R Tracy K Johnson C | 2014 | J Oral Maxillofac Surg2014，72，3： | 1 |
| 14 | Electrochemical deposition of vanadium oxide in the presence of surfactants-A novel approach toward high-rate lithium battery cathodes显示文摘 | ZHANG J G TRACY C E | 2000 | Electrochemical and Solid State Letters2000，3，4： | 1 |
| 15 | Preserving biodiversity : species in landscapes 显示文摘 | Tracy C R Brussard P F | 1994 | Ecological Applications1994，4，2： | 1 |
| 16 | Physical vapor transport growth of large AlN crystals 显示文摘 | TRACY W CHRIS C R SINGH N B | 2003 | J of Crystal Growth2003，250，1： | 1 |
| 17 | Beneficial effects of plants in the remediation of soil and ground- water contaminated with organic materials显示文摘 | SHIMP J F TRACY J C DAVIS L C | 1993 | Environment Science Technology1993，，23： | 1 |
| 18 | Stand-alone photovoltaic-powered electrochromic smart window显示文摘 | Deb S K Lee S H Tracy C E | 2001 | Electrochimica Acta2001，46，： | 1 |
| 19 | On orthogonal and symplectic matrix ensembles 显示文摘 | Tracy C A and Widom H | 1996 | Communications in Mathematical Physics1996，177，3： | 1 |
| 20 | On orthogonal and symplectic matrix ensembles 显示文摘 | TRACY C A WIDOM H | 1996 | Commun Math Phys1996，177，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员