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| 1 | New aspects in celiac disease显示文摘Celiac disease (CD) is a common autoimmune disorder characterized by an immune response to ingested gluten and has a strong HLA association with HLA- DQ2 and HLA-DQ8 molecules, but human HLA-DQ risk factors do not explain the entire genetic susceptibility to gluten intolerance. CD is caused by the lack of immune tolerance (oral tolerance) to wheat gluten. In this sense, the expression of soluble HLA-G in CD is of special interest because the molecule plays an important role in the induction of immune tolerance. The enhanced expression of soluble HLA-G found in CD may be part of a mechanism to restore the gluten intolerance. In this editorial, we review recent progress in understanding CD in relation to its prevalence, diagnosis and possible mechanisms of pathogenesis. | MI Torres MA López Casado A Ríos | 2007 | World Journal of Gastroenterology2007，13，8： | 10 |
| 2 | Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy显示文摘AIM: To evaluate the association between serum concentrations of S100β in patients with cirrhosis and the presence of low grade hepatic encephalopathy(HE).METHODS: This was a cross-sectional study. The population was categorized into four groups healthy subjects, cirrhosis without HE, cirrhosis with covert hepatic encephalopathy(CHE) and cirrhosis with overt HE. Kruskal-Wallis, Mann Whitney's U with Bonferroni adjustment Spearman correlations and area under the ROC were used as appropriate.RESULTS: A total of 61 subjects were included, 46 cirrhotic patients and 15 healthy volunteers. S100β values were different among all groups, and differences remained significant between groups 1 and 2(P < 0.001), and also between groups 2 and 3(P = 0.016), but not between groups 3 and 4. In cirrhotic patients with HE S100β was higher than in patients without HE [0.18(0.14-0.28) ng/m L vs 0.11(0.06-0.14) ng/m L, P < 0.001]. There was a close correlation between serum concentrations of S100β and psychometric hepatic encephalopathy score in patients with cirrhosis without HE compared to the patients with cirrhosis with CHE(r =-0.413, P = 0.019). ROC curve analysis yielded > 0.13 ng/m L as the best cutoff value of S100β for the diagnosis of HE(sensitivity 83.3%, specificity 63.6%).CONCLUSION: Serum concentrations of S100β are higher in patients with cirrhosis than in healthy volunteers, and are further increased in the presence of hepatic encephalopathy. The results suggest that serum biomarkers such as S100β could help in the correct characterization of incipient stages of HE. | Andrés Duarte-Rojo Astrid Ruiz-Margáin Ricardo U Macias-Rodriguez Francisco Javier Cubero José Estradas-Trujillo Rosa Ma Munoz-Fuentes Aldo Torre | 2016 | World Journal of Gastroenterology2016，22，17： | 4 |
| 3 | Occult hepatitis B virus infection among Mexican human immunodeficiency virus-1-infected patients显示文摘AIM: To determine the frequency of occult hepatitis B infection(OHBI) in a group of human immunodeficiency virus(HIV)-1+/ hepatitis B surface antigen negative(HBsAg)- patients from Mexico. METHODS: We investigated the presence of OHBI in 49 HIV-1+/HBsAg- patients. Hepatitis B virus(HBV) DNA was analyzed using nested PCR to amplify the Core(C) region and by real-time PCR to amplify a region of the S and X genes. The possible associations between the variables and OHBI were investigated using Pearson's χ2 and/or Fisher's exact test.RESULTS: We found that the frequency of OHBI was 49% among the group of 49 HIV-1+/HBsAg- patients studied. The presence of OHBI was significantly associated with the HIV-1 RNA viral load [odds ratio(OR) = 8.75; P = 0.001; 95%CI: 2.26-33.79] and with HIVantiretroviral treatment with drugs that interfere with HBV replication(lamivudine, tenofovir or emtricitabine)(OR = 0.25; P = 0.05; 95%CI: 0.08-1.05). CONCLUSION: The OHBI frequency is high among 49 Mexican HIV-1+/HBsAg- patients and it was more frequent in patients with detectable HIV RNA, and less frequent in patients who are undergoing HIV-ARV treatment with drugs active against HBV. | Ma Teresa Alvarez-Muoz Angelica Maldonado-Rodriguez Othon Rojas-Montes Rocio Torres-Ibarra Fernanda Gutierrez-Escolano Guillermo Vazquez-Rosales Alejandro Gomez Onofre Muoz Javier Torres Rosalia Lira | 2014 | World Journal of Gastroenterology2014，20，37： | 3 |
| 4 | A model for the induction of aplastic anemia by subcutaneous administration of benzene in mice 显示文摘 | Lezama VR Escorcia BE Torres MA | 2001 | Toxiology2001，162，3： | 1 |
| 5 | COPD disease and malnutrition显示文摘 | Casanova Macario C de Torres Tajes JP Paimero MA | 2009 | Arch Bronconeumol2009，45，4： | 1 |
| 6 | Comparative genomics of yeast species:new insights into their biology显示文摘 | Herrero E de la Torre MA Valentin E | 2003 | Int Microbiol2003，6，3： | 1 |
| 7 | Comparison of treatment tolerance and outcomes in patients with cervical cancer treated with concurrent chemoradiotherapy in a prospective randomized trial or with standard treatment显示文摘 | Torres MA Jhingran A Thames HD Jr | 2008 | Int J Radial Oncol Biol Phys2008，70，1： | 1 |
| 8 | Hair cell regeneration in the bullfrog vestibular otolith organs following aminogtycoside toxicity显示文摘 | Baird RA Torres MA Schuff NR | 1993 | Hear Research1993，65，： | 1 |
| 9 | Somatic mutation in individual liver cysts supports a two-hit model for cystogenesis in autosomal dominant polycystic kidney disease显示文摘 | Watnick TJ Torres VE Gandolph MA | 2000 | Mol Cell2000，21，2： | 1 |
| 10 | A new approachusing tissue alkaline phosphatase histochemistry to identifyCrohn′s disease显示文摘 | Torres MI Lorite P Lpez-Casado MA | 2007 | Pathol Res Pract2007，203，6： | 1 |
| 11 | Potential role of the IL-33/ST2 axis in celiac disease显示文摘IL-33/ST2 轴在几织物特定的自体免疫的疾病的致病被含有。腹的疾病(CD ) 是主要基因因素(HLA-DQ2/DQ8 ) 和为危险性的 etiologic (饮食的面筋) 在被知道的唯一的自体免疫的疾病。我们测量了浆液层次和 IL-33 和它的受体的坚定的肠的织物表示在病人与的可溶的 ST2 与疾病活动调查他们的协会的 CD。没有 CD, IL-33 和 sST2 的浆液和织物层次与在控制病人的那些相比在有 CD 的病人是显著地更高的。我们证明显著地从大麦和小麦麦胶蛋白质提取的有毒的肽从腹的病人在有教养的外部血 mononuclear 房间刺激 IL-33 和 ST2 的生产,强烈含有在 CD 的致病的 IL-33/ST2 轴。在织物和浆液的 IL-33 和它的受体 ST2 的高水平反映一个活跃煽动性的状态并且可以为疾病活动代表潜在的 biomarker。IL-33/ST2 版本,行动的模式,和规定的更好的理解将是关键的开发治疗学指向 IL-33/ST2 小径到对待 CD。 | Lopez-Casado MA Lorite P Palomeque T Torres MI | 2017 | Cellular & Molecular Immunology2017，14，3： | 1 |
| 12 | Spermatic cord torsion, reactive oxygen species and ischemnia-reperfusion injury 显示文摘 | FILHO DW TORRES MA BORDIN AL | 2004 | Mol Aspects Med2004，75，12： | 1 |
| 13 | Reduced mRNA abu ndance of the main enzxymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma显示文摘 | Avila MA Berasain C Torres L | 2000 | J Hepatol2000，33，6： | 1 |
| 14 | Muscarinic receptors participation in angiogenic response induced by macrophages from mammary adenocarcinoma-bearing mice显示文摘 | de la Torre E Davel L Jasnis MA | 2005 | Breast Cancer Res2005，7，3： | 1 |
| 15 | Clinical outbreak of linezolid-resistant Staphylococcus aureus in an intensive care unit显示文摘 | Sanchez Garcia M De la Torre MA Morales G | | 0，，： | 1 |
| 16 | Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma显示文摘 | Avila MA Berasain C Torres L | 2000 | J Hepatol2000，33，6： | 1 |
| 17 | Effect of superior cervical ganglionectomy on catecholamine concentration in rat cochlea显示文摘 | Gil - Loyzaga P Vicente - Torres MA Arce A | 1998 | Brain Res1998，779，： | 1 |
| 18 | Functions of the respiratory burstoxidase in biotic interactions, abiotic stress anddevelopment 显示文摘 | Torres MA Dangl JL | 2005 | Current Opinion in Plant Biology2005，8，4： | 1 |
| 19 | Primary malignant melanoma of urinary bladder: immunohistochemical study of a new case and review of the literature显示文摘 | De torres I Fortuno MA Raventos A | 1995 | J Urol1995，154，2： | 1 |
| 20 | Spermatic cord torsion,reactive oxygen and nitrogen species and ischemnia reperfusion injury显示文摘 | FILHO DW TORRES MA BORDIN AL | 2004 | Mol Aspects Med2004，25，122： | 1 |
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