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21篇 您的检索式:作者名="Tishkov"
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1Role of digital single-operator cholangioscopy in the diagnosis and treatment of biliary disorders显示文摘Due to the need for improvement in the diagnosis and minimally invasive therapy of the bile duct disorders new technologies for cholangioscopy have been recently developed. Per-oral cholangioscopy has become an important diagnostic and therapeutic tool leading to avoidance of aggressive and unnecessary surgery in many clinical scenarios. This paper focuses on the newly developed SpyGlass DS technology, its advantages, and the technique of single-operator cholangioscopy(SOC), biliary indications and possible adverse events. We also review the available literature; discuss the limitations and future expectations.Digital SOC(D-SOC) is a useful technique, which provides endoscopic imaging of the biliary tree, optical diagnosis, biopsy under direct vision and therapeutic interventions. The implementations are diagnostic and therapeutic. Diagnostic indications are indeterminate biliary strictures, unclear filling defects, staging of cholangiocarcinoma, staging of ampullary tumors(extension into the common bile duct), unclear bile duct dilation, exploring cystic lesions of the biliary tree,unexplained hemobilia, posttransplant biliary complications. Therapeutic indications are lithotripsy of difficult stones, retrieval of migrated stents, foreign body removal, guide wire placement, transpapillary gallbladder drainage and endoscopic tumor ablative therapy. Most studied and established indications are the diagnosis of indeterminate biliary stricture and intraductal lithotripsy of difficult stones. The adverse events are not different and more common compared to those of Endoscopic retrograde cholangiopancreatography(ERCP)alone. D-SOC is a safe and effective procedure, adjunct to the standard ERCP and the newly available digital technology overcomes many of the limitations of the previous generations of cholangioscopes.Petko Karagyozov Irina Boeva Ivan Tishkov 2019World Journal of Gastrointestinal Endoscopy2019,11,1:22
2Post-liver transplant biliary complications:Current knowledge and therapeutic advances显示文摘Liver transplantation is the current standard of care for end-stage liver disease and an accepted therapeutic option for acute liver failure and primary liver tumors.Despite the remarkable advances in the surgical techniques and immunosuppressive therapy,the postoperative morbidity and mortality still remain high and the leading causes are biliary complications,which affect up to one quarter of recipients.The most common biliary complications are anastomotic and non-anastomotic biliary strictures,leaks,bile duct stones,sludge and casts.Despite the absence of a recommended treatment algorithm many options are available,such as surgery,percutaneous techniques and interventional endoscopy.In the last few years,endoscopic techniques have widely replaced the more aggressive percutaneous and surgical approaches.Endoscopic retrograde cholangiography is the preferred technique when duct-to-duct anastomosis has been performed.Recently,new devices and techniques have been developed and this has led to a remarkable increase in the success rate of minimally invasive procedures.Understanding the mechanisms of biliary complications helps in their early recognition which is the prerequisite for successful treatment.Aggressive endoscopic therapy is essential for the reduction of morbidity and mortality in these cases.This article focuses on the common post-transplant biliary complications and the available interventional treatment modalities.Irina Boeva Petko Ivanov Karagyozov Ivan Tishkov 2021World Journal of Hepatology2021,13,1:11
3珠穆朗玛地区伞形科植物的分类学研究(英文)显示文摘Five species new for Chinese flora have been shown on the basis of the gatherings from northern slopes of Qomolangma Feng (Everest Mt. ). They belong to the genera Physospermopsis, Pleurospermum, Pimpinella, and Schulzia. A new genus, Oreocomopsis and its new species, O. xizangensis, have been described. Critical comments on these and some other South Xizang Umbelliferae are presented.M. G. Pimenov E. V. Kljuykov A. A. Tishkov 1996植物分类学报1996,34,1:6
4Crystal structures of complexes of NAD+-dependent formate dehydrogenase from methylotrophic bacterium Pseudomonas sp. 101 with formate显示文摘E. V. Filippova K. M. Polyakov T. V. Tikhonova T. N. Stekhanova K. M. Boiko I. G. Sadykhov V. I. Tishkov V. O. Popov N. Labru 2006Crystallography Reports2006,,4:1
5Endoscopic ultrasound-guided biliary drainage-current status and future perspectives显示文摘Endoscopic retrograde cholangiopancreatography(ERCP)with stenting is the treatment modality of choice for patients with benign and malignant bile duct obstruction.ERCP could fail in cases of duodenal obstruction,duodenal diverticulum,ampullary neoplastic infiltration or surgically altered anatomy.In these cases percutaneous biliary drainage(PTBD)is traditionally used as a rescue procedure but is related to high morbidity and mortality and lower quality of life.Endoscopic ultrasound-guided biliary drainage(EUS-BD)is a relatively new interventional procedure that arose due to the development of curvilinear echoendoscope and the various endoscopic devices.A large amount of data is already collected that proves its efficacy,safety and ability to replace PTBD in cases of ERCP failure.It is also possible that EUS-BD could be chosen as a first-line treatment option in some clinical scenarios in the near future.Several EUS-BD techniques are developed EUS-guided transmural stenting,antegrade stenting and rendezvous technique and can be personalized depending on the individual anatomy.EUS-BD is normally performed in the same session from the same endoscopist in case of ERCP failure.The lack of training,absence of enough dedicated devices and lack of standardization still makes EUS-BD a difficult and not very popular procedure,which is related to life-threatening adverse events.Developing training models,dedicated devices and guidelines hopefully will make EUS-BD easier,safer and well accepted in the future.This paper focuses on the technical aspects of the different EUS-BD procedures,available literature data,advantages,negative aspects and the future perspectives of these modalities.Petko Ivanov Karagyozov Ivan Tishkov Irina Boeva Kiril Draganov 2021World Journal of Gastrointestinal Endoscopy2021,13,12:1
6Application of fluidized carrier to bacterial sulphate-reduction in industrial wastewaters purification显示文摘Vladislav Somlev Savs Tishkov 0,,01:1
7Application of Fluidized Carrier to Bacterial Sulphate redaction in Industrial Wastcwaters Purification显示文摘Vladislav Somlev Sava Tishkov 1992Biotechnology Techniques1992,6,1:1
8Protein engineering of formate dehydrgenase 显示文摘Tishkov VI Popov VO 2006Biomol Eng2006,23,23:1
9Structure-guided al- teration of coenzyme specificity of formate dehydrogenase by sat- uration mutagenesis to enable efficient utilization of NADP+ 显示文摘Andreadeli A Platis D Tishkov V 2008FEBS J2008,275,15:1
10D-amino acid oxidase:physiological role and applications显示文摘Khoronenkova SV Tishkov VI 0,,13:1
11Application of fluidized carrier to bacterial sulphate-reduction in industrial wastewaters purification显示文摘Vladislav Somlev Sava Tishkov 1992Biotechnology Techniques1992,,1:1
12Application of fluidized carrier to bacterial sulphate - reduction in industrial wastewaters purification 显示文摘Vladislav Somlev Sava Tishkov 1992Biotechnology Techniques1992,6,1:1
13Catalytic mechanism and appli- cation of formate dehydrogenase 显示文摘TISHKOV V I POPOV V O 2004Biochemistry2004,69,11:1
14Catalytic mechanism and application of formate dehydrogenase显示文摘Tishkov V I Popov V O 2004Biochemistry (Moscow)2004,69,11:1
15Application of fluidized earriex to bacterial sulphate - reduction in industrial wastewaters purification 显示文摘Vladislav Somlev Sava Tishkov 1992Biotechnology Techniques1992,6,1:1
16Immunosuppressive therapy with cyclophosphamide and prednisolone in severe idiopathic membranous nephropathy显示文摘Kibriya MG Tishkov I Nikolov D 0,,02:1
17Application of Fluidized Carrier to Bacterial Sulphate-reduction in Industrial Wastewaters Purification显示文摘Vladislav Scmlev Sava Tishkov 1992Biotechnology Techniques1992,6,1:1
18Application of Fluidized Carrier to Bacterial Sulphate--reduction in Indus- trial Wastewaters Purification显示文摘Vladislav Somlev Sara Tishkov 1992Biotechnology Techniques1992,6,1:1
19重组具有改良特性的D-氨基酸氧化酶显示文摘在大肠杆菌细胞中表达三角酵母D-氨基酸氧化酶,并对重组酶的性质进行了研究。制备的单一突变体与野生型酶相比,具有2.4倍的热稳定性或底物特异性变化光谱。结果显示突变的TvDAAO在氧化头孢菌素中催化效果优于野生型酶。并将一个突变的重组TvDAAO制备成结晶,并解析了2.8?分辨率下的晶体结构。S.V Khoronenkova V.I. Tishkov 2008生物工程学报2008,24,12:0
20创造城市的浪漫显示文摘真正的生活探索者,是敢于自己动手创造那些梦里才会有的玩意,敢于超越现实向未来进发。这些充满穿越感的明月、花园、路灯、停车场,是设计师、艺术家们疯狂的尝试,给予城市建设新的启发。June Leonid Tishkov 2012中华手工2012,,11:0
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