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384篇 您的检索式:作者名="Thomson F"
    题名 作者 年代 出处 被引量
1健康领域的文化能力显示文摘1背景 尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,2:5
2Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease显示文摘AIM: To investigate whether accelerated catabolism of ganglioside and decreased ganglioside content contribute to the etiology of pro-inflammatory intestinal disease. METHODS: Intestinal mucosa from terminal ileum or colon was obtained from patients with ulcerative colitis or inflammatory Crohn's disease(n = 11) undergoing bowel resection and compared to control samples of normal intestine from patients with benign colon polyps(n = 6) and colorectal cancer(n = 12) in this observational case-control study. Gangliosides and phospholipids of intestinal mucosa were characterized by class and ceramide or fatty acid composition using liquid chromatography triple-quad mass spectrometry. Content and composition of ganglioside classes GM1, GM3, GD3, GD1 a, GT1 and GT3 were compared among subject groups. Content and composition of phospholipid classes phosphatidylcholine(PC) and phosphatidylethanolamine were compared among subject groups. Unsaturation index of individual ganglioside and phospholipid classes was computed and compared among subject groups. Ganglioside catabolism enzymes beta-hexosaminidase A(HEXA) and sialidase-3(NEU3) were measured in intestinal mucosa using western blot and compared among subject groups. RESULTS: Relative GM3 ganglioside content was 2-fold higher(P < 0.05) in intestine from patients with inflammatory bowel disease(IBD) compared to control intestine. The quantity of GM3 and ratio of GM3/GD3 was also higher in IBD intestine than control tissue(P < 0.05). Control intestine exhibited 3-fold higher(P < 0.01) relative GD1 a ganglioside content than IBD intestine. GD3 and GD1 a species of ganglioside containing three unsaturated bonds were present in control intestine, but were not detected in IBD intestine. The relative content of PC containing more than two unsaturated bonds was 30% lower in IBD intestine than control intestine(P < 0.05). The relative content of HEXA in IBD intestine was increased 1.7-fold(P < 0.05) and NEU3 was increased 8.3-fold(P < 0.01) compared to normal intestine. Intestinal mucosa in IBD is characterized by increased GM3 content, decreased GD1 a, and a reduction in polyunsaturated fatty acid constituents in GD3, GD1 a and PC.CONCLUSION: This study suggests a new paradigm by proposing that IBD occurs as a consequence of increased metabolism of specific gangliosides.John J Miklavcic Glen K Shoemaker Vera C Mazurak M Tom Clandinin Tasha DL Hart Kareena L Schnabl Gordon M Lees Bodil MK Larsen Oliver F Bathe Alan BR Thomson M Tom Clandinin 2015World Journal of Gastroenterology2015,21,35:3
3文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响 政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,3:2
4Comparison of Torsion and Plane-Strain Compression for Predicting Mean Yield Strength in Single and Multiple-Pass Flat Rolling Using Lead to Model Hot Steel显示文摘Wong S F Hodson P D Thomson P F 1995Journal of Materials Processing Technology1995,53,:1
5Whole-body MRI for metastases screening:a preliminary study using 3D VIBE sequences with automatic subtraction between noncontrast and contrast enhanced images显示文摘Thomson V Pialat JB Gay F 2008Am J Clin Oncol2008,31,3:1
6Applications of MOSFET dosimeters on MIR and BION satellites显示文摘 Thomson I Sultan N 1997IEEE TransNuclSci1997,44,6:1
7Three Dimensional Simulation of the Edge Rolling Process by the Explicit FiniteElement Method显示文摘Chung W K Choi S K Thomson P F 1993Journal of Materials Processing Technology1993,38,:1
8Effects of temperature, water content and nitrogen fertilisation on emissions of nitrous oxide by soils显示文摘K.A Smith P.E Thomson H Clayton I.P Mctaggart F Conen 1998Atmospheric Environment1998,,19:1
9医疗卫生保健文化的反思及促进健康与文化融合的建议显示文摘1医疗卫生保健文化的反思1.1健康文化与医学知识如果医务人员有充足的时间对患者进行诊断并帮助患者进行社区护理,就可在节省卫生费用的同时改善健康结果。整合型社区护理能缩小不同文化背景和群体健康需求的差异。然而,全球范围内对整合型社区护理的投入较少,原因之一就是20世纪对临床服务的重视弱化了卫生服务提供过程中的同情心理。当然,患者也对医学知识存在显性和隐性的影响(特别是当其因不遵医嘱而受到指责时)。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson JWoolf K 2016中国卫生政策研究2016,9,4:1
10Pemistent cough in children:overnsc of medications显示文摘Thomson F Mastem IB Chang AB 2002Paediatr Child Heal2002,38,:1
11Whole body MRI for me- tastases screening: a preliminary study using 3D VIBE sequences with automatic subtraction between noncontrast and contrast en- hanced images显示文摘Thomson V Pialat J B Gay F 2008Am J Clin Oncol2008,31,3:1
12Isolated main pancreatic duct injuries spectrum and management 显示文摘Buccimazza I Thomson SR Anderson F 2006Am J Surg2006,191,4:1
13Com- bining value and price to make purchase decisions in business markets显示文摘Anderson J C Thomson J B L Wynstra F 2000Intermational Journal of Research in Marketing2000,17,4:1
14The nature of haemorrhoids显示文摘THOMSON W H F 1975British Journal of Surgery1975,62,7:1
15Calculation of microstrip discontinuity inductances显示文摘THOMSON A F GOPINATH A 1975IBID1975,23,:1
16Agglomeration and sintering in annealed FePt nanopartide assemblies studied by small angle neutron scattering and X-ray diffraction 显示文摘Thomson T Lee S L Toney M F 2005Physical Review B2005,72,06:1
17Prevalence and patterns of anxiety and depression in patients undergoing elective percutaneous transluminal coronary angioplasty 显示文摘Astin F Jones K Thomson DR 2005Heart Lung: The Journal of Acute and Critical Care2005,34,6:1
18Meeting the challenges in language for specific purposes:The incorporation of sociolinguistics and learner autonomy into course design 显示文摘Thomson C K Masumi-so H & Osho F 2001Japanese Studies2001,211,:1
19Method for measurement of self- renewal capacity of clonogenic cells from biopsies of metastatic human malignant melanoma显示文摘Thomson S P Meyskens F L Jr 1982Cancer Res1982,42,:1
20Evolution and performance of city of San Diego pilot scale aquatic wastewater treatment system using water hyacinth 显示文摘TCHOBANOGLOUS G MAITSKI F K THOMSON K 1989J WPCF1989,61,:1
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