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| 1 | New insights on premature ejaculation: a review of :lefinition, classification, prevalence and treatmeni显示文摘关于早泄(PE ) 的定义,分类和流行有进行中的争论。PE 的第一个基于证据的定义与终生的 PE 被限制到异性爱的人从事阴道交际。不幸地,有 PE 的抱怨的许多病人不满足这些标准。然而,这些人能作为 PE 子类型,也就是获得的 PE,自然可变 PE 或象早熟一样之一被诊断射精的机能障碍。不过,这些子类型的有效性被证据还没支持了。一个普遍接受的 PE 定义的缺席和为数据获得的标准的缺乏导致了报导了冲突率的流行研究。20 % 的高流行; -30%可能由于在如此的调查被进行的时间在定义使用的含糊的术语。尽管当为基于人口的流行研究询问了时,许多人可以抱怨 PE,仅仅他们的一些将活跃地为他们的抱怨寻求治疗,尽管大多数这些病人将定义与 PE 适合的症状。获得的 PE 病人的抱怨可能是更严重的,而经历象早熟一样的病人的抱怨射精的机能障碍与 PE 的各种各样的形式在人之中似乎最少严重。尽管众多的治疗形式为 PE 的管理被建议了,仅仅抗抑郁剂和热门麻木的乳脂当前被证明了有效。当任何一个都没被规章的机构同意了治疗形式,进一步的研究不管多么必须被带为 PE 开发有益的治疗策略。 | Ege C Serefoglu Theodore R Saitz | 2012 | Asian Journal of Andrology2012，14，6： | 34 |
| 2 | Sleep,immunity and inflammation in gastrointestinal disorders显示文摘Sleep disorders have become a global issue,and discovering their causes and consequences are the focus of many research endeavors.An estimated 70 million Americans suffer from some form of sleep disorder.Certain sleep disorders have been shown to cause neurocognitive impairment such as decreased cognitive ability,slower response times and performance detriments.Recent research suggests that individuals with sleep abnormalities are also at greater risk of serious adverse health,economic consequences,and most importantly increased all-cause mortality.Several research studies support the associations among sleep,immune function and inflammation.Here,we review the current research linking sleep,immune function,and gastrointestinal diseases and discuss the interdependent relationship between sleep and these gastrointestinal disorders.Different physiologic processes including immune system and inflammatory cytokines help regulate the sleep.The inflammatory cytokines such as tumor necrosis factor,interleukin-1(IL-1),and IL-6 have been shown to be a significant contributor of sleep disturbances.On the other hand,sleep disturbances such as sleep deprivation have been shown to up regulate these inflammatory cytokines.Alterations in these cytokine levels have been demonstrated in certain gastrointestinal diseases such as inflammatory bowel disease,gastro-esophageal reflux,liver disorders and colorectal cancer.In turn,abnormal sleep brought on by these diseases is shown to contribute to the severity of these same gastrointestinal diseases.Knowledge of these relationships will allow gastroenterologists a great opportunity to enhance the care of their patients. | Tauseef Ali James Choe Ahmed Awab Theodore L Wagener William C Orr | 2013 | World Journal of Gastroenterology2013，19，48： | 15 |
| 3 | Transanal polypectomy using single incision laparoscopic instruments显示文摘Transanal excision of rectal polyps with laparoscopic instrumentation and a single incision laparoscopic port is a novel technique that uses technology originally developed for abdominal procedures from the natural orifice of the rectum. Transanal endoscopic microsurgery (TEM) is a well established surgical approach for certain benign or early malignant lesions of the rectum, under specific indications. Our technique is a hybrid technique of transanal surgery, a reasonable method for polyp resection without the need of the sophisticated and expensive instrumentation of TEM which can be applied whenever endoscopic or conventional transanal surgical removal is not feasible. | Dimitrios Dardamanis Dimitrios Theodorou George Theodoropoulos Andreas Larentzakis Maria Natoudi Georgia Doulami Christina Zoumpouli Haridimos Markogiannakis Stylianos Katsaragakis George C Zografos | 2011 | World Journal of Gastrointestinal Surgery2011，3，4： | 6 |
| 4 | Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma-a rationale for a molecular targeting strategy?显示文摘AIM: To define the (co-)expression pattern of target receptor-tyrosine-kinases (RTK) in human gastric adenocarcinoma. METHODS: The (co-)expression pattern of VEGFR1-3,PDGFRα/b and EGFR1 was analyzed by RT-PCR in 51 human gastric adenocarcinomas. In addition,IHC staining was applied for confirmation of expression and analysis of RTK localisation. RESULTS: The majority of samples revealed a VEGFR1 (98%),VEGFR2 (80%),VEGFR3 (67%),PDGFRα (82%) and PDGFRβ(82%) expression,whereas only 62% exhibited an EGFR1 expression. 78% of cancers expressed at least four out of six RTKs. While VEGFR1-3 and PDGFRα revealed a predominantly cytoplasmatic staining in tumor cells,accompanied by an additional nuclear staining for VEGFR3 ,EGFR1 was almost exclusively detected on the membrane of tumor cells. PDGFRβ was restricted to stromal pericytes,which also depicted a PDGFRα expression.receptor-tyrosine-kinases coexpression in gastric adenocarcinoma and might therefore encourage an application of multiple-target RTK-inhibitors within a combination therapy. | Daniel Drescher Markus Moehler Ines Gockel Kirsten Frerichs Annett Müller Friedrich Dünschede Thomas Borschitz Stefan Biesterfeld Martin Holtmann Thomas Wehler Andreas Teufel Kerstin Herzer Thomas Fischer Martin R Berger Theodor Junginger Peter R Galle Carl C Schimanski | 2007 | World Journal of Gastroenterology2007，13，26： | 4 |
| 5 | Hepatotoxicity of anti-inflammatory and analgesic drugs:ultrastructural aspects显示文摘与导致药的肝疾病的增加的发生,正在被尝试更好在这些经常危及生活的反应后面理解机制。止痛剂和反煽动性的药是展出 hepatotoxicity 的一个主要的组。我们考察关于这些反应的研究,集中于极端结构的调查结果,它可以贡献理解和导致药的肝疾病的可能的回避。我们也在与抗氧化剂 N-acetylcysteine 或 P-glycoprotein 禁止者 verapamil 独自或在联合暴露于 acetaminophen 的临床的材料和有教养的房间上介绍一些原来的观察。 | Irena MANOV Helen MOTANIS Idan FRUMIN Theodore C IANCU | 2006 | Acta Pharmacologica Sinica2006，27，3： | 2 |
| 6 | 2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines显示文摘 | Mariell Jessup William T. Abraham Donald E. Casey Arthur M. Feldman Gary S. Francis Theodore G. Ganiats Marvin A. Konstam Donna M. Mancini Peter S. Rahko Marc A. Silver Lynne Warner Stevenson Clyde W. Yancy Sharon Ann Hunt William T. Abraham Marshall H. C | 2009 | Circulation2009，，14： | 2 |
| 7 | Metabolic adaptations of plant respiration to nutritional phosphate deprivation 显示文摘 | Theodorou M E Plaxton W C | 1993 | Plant Physiol1993，101，： | 1 |
| 8 | Tracking and followup of 16, 915 Adolescents: Minimizing Attrition Bias 显示文摘 | Theodore C Dennis R Melbourne F | 1997 | Controlled Clinical Trails1997，18，： | 1 |
| 9 | CV706,a prostate cancer-specific adenovirus variant,in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity显示文摘 | Yu C Theodore D Jeanette D | 2001 | Cancer Res2001，61，14： | 1 |
| 10 | Quantitative computed tomography in the evaluation of spinal osteoporosis following spinal cord injury显示文摘 | Liu C Theodorou ID Theodorou S | 2000 | Osteoporosis Int2000，11，10： | 1 |
| 11 | Image quality of sparse -aperture designs for remote sensing显示文摘 | Robert D F Theodore A T Jason R C | 2002 | Optical Engineering2002，41，8： | 1 |
| 12 | Risk Factors for Work-related Low Back Pain in the Peoples Republic of China显示文摘 | Kezhi J Gary S Theodore C | 2000 | Int J Environ Occup Health2000，6，1： | 1 |
| 13 | Observations and issues on mechanisms of grain refinement during ECAP process显示文摘 | Yuntian Theodore Zhu Terry C Lowe | 2000 | Materials Science & Engineering A2000，，1： | 1 |
| 14 | Determination of dapsone in meat and milk by liquid chromatography tandem mass spectrometry显示文摘 | Hadjigeorgiou M Papaehrysostomou C H Theodorou Z | 2009 | Analytica Chimica Aeta2009，637，12： | 1 |
| 15 | Excitation-emission-matrix fluorescence spectroscopy applied to humic acid bands in coral reefs显示文摘 | Matthews B J H Jones A C Theodorou N K | 1996 | Mar Chem1996，55，34： | 1 |
| 16 | NASA thermal control technologies for robotic spacecraft显示文摘 | THEODORE D S GAJANANA C B B | 2003 | Applied Thermal Engineering2003，23，： | 1 |
| 17 | NASA thermal control technologies for robotic spacecraft 显示文摘 | THEODORE D SWANSON GAJANANA BIRUR C | 2003 | Applied Thermal Engineering2003，23，： | 1 |
| 18 | Ilearn self-learning defect classifier显示文摘 | CHRIS A C THEODORE Y F CHARLES F | 1998 | Iron and Steel Engineer1998，75，8： | 1 |
| 19 | A systematic and quantitative approach to improve water use efficiency in agri- culture 显示文摘 | Theodore C Hsiao Pasquale Steduto Elias Fereres | 2007 | Irrigation Science2007，，25： | 1 |
| 20 | Ru l e-B a s e d Cont ex tAssessment in Smart Cities显示文摘 | Beibei Hu Theodore Patkos AbdelghaniCh i b a n i Ya c i ne A m i r a t | 2012 | Web Reasoning andRule Systems Lecture Notes in Computer Science2012，，7497： | 1 |
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