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| 1 | Relationship between intubation rate and continuous positive airway pressure therapy in the prehospital setting显示文摘BACKGROUND: To determine whether the prehospital use of continuous positive airway pressure(CPAP) therapy is associated with a reduced rate of endotracheal intubation in patients with an acute respiratory disorder brought to the emergency department(ED).METHODS: We reviewed medical records of patients with acute respiratory distress who had been treated with CPAP in the Mobile Intensive Care Unit(MICU) from January 2010 to December 2011. These records were compared with those of patients who received standardized care without CPAP in the MICU from January 2004 to December 2004. Categorical variables were summarized as frequencies and compared between groups using Fisher's exact test or the Chi-square test. Continuous variables were summarized as medians(interquartile range), and comparison between the groups was made using Wilcoxon's rank-sum test. The relationship between CPAP and intubation rate was determined using multivariable logistic regression analysis of propensity scores. The results were presented as odds ratio(OR), 95% confidence interval(CI), and P value for test effect. The adequacy of the model was calibrated using Hosmer and Lemeshow's goodness-of-fit test. P<0.05 was considered statistically significant.RESULTS: The records of 785 patients were reviewed. Of the 215 patients treated with CPAP in the MICU, 13% were intubated after admission. In contrast, of the 570 patients who did not receive CPAP, 28% were intubated after ED admission. Unadjusted logistic regression analysis showed that patients who had been treated with CPAP were less likely to be intubated than those without CPAP treatment(OR=0.37, 95% CI, 0.24–0.57, P<0.0001). With propensity scores adjusted, multivariate logistic regression analysis showed that CPAP treatment was associated with a 62% reduction of intubation(OR=0.384, 95%CI, 0.25–0.60, P≤0.0001).CONCLUSIONS: In patients with acute respiratory disorder, there was a relationship between CPAP therapy and the decreased intubation rate. CPAP therapy was feasible in prehospital management of patients with respiratory distress. | Nigel Knox Ogedegbe Chinwe Nyirenda Themba Feldman Joseph Ashtyani Hormoz | 2015 | World Journal of Emergency Medicine2015，6，1： | 5 |
| 2 | Esophageal squamous cell cancer in a highly endemic region显示文摘AIM: To identify risk factors associated with esophageal cancer in Zambia and association between dietary intake and urinary 8-iso prostaglandin F2α(8-iso PGF2α).METHODS: We conducted a prospective, case control study at the University Teaching Hospital. Subjects included both individuals admitted to the hospital and those presenting for an outpatient upper endoscopy. Esophageal cancer cases were compared to age and sex-matched controls. Cases were defined as patients with biopsy proven esophageal cancer; controls were defined as subjects without endoscopic evidence ofesophageal cancer. Clinical and dietary data were collected using a standard questionnaire, developed a priori. Blood was collected for human immunodeficiency virus(HIV) serology. Urine was collected, and 8-iso PGF2α was measured primarily by enzyme-linked immunosorbent assay and expressed as a ratio to creatinine.RESULTS: Forty five controls(mean age 54.2 ± 15.3, 31 male) and 27 cases(mean age 54.6 ± 16.4, 17 males) were studied. Body mass index was lower in cases(median 16.8) than controls(median 23.2), P = 0.01. Histopathologically, 25/27(93%) were squamous cell carcinoma and 2/27(7%) adenocarcinoma. More cases smoked cigarettes(OR = 11.24, 95%CI: 1.37-92.4, P = 0.02) but alcohol consumption and HIV seropositivity did not differ significantly(P = 0.14 for both). Fruit, vegetables and fish consumption did not differ significantly between groups(P = 0.11, 0.12, and 0.10, respectively). Mean isoprostane level was significantly higher in cases(0.03 ng/mg creatinine) than controls(0.01 ng/mg creatinine)(OR = 2.35, 95%CI: 1.19-4.65, P = 0.014).CONCLUSION: Smoking and isoprostane levels were significantly associated with esophageal cancer in Zambians, but diet, HIV status, and alcohol consumption were not. | Akwi W Asombang Violet Kayamba Mpala M Lisulo Kathryn Trinkaus Victor Mudenda Edford Sinkala Stayner Mwanamakondo Themba Banda Rose Soko Paul Kelly | 2016 | World Journal of Gastroenterology2016，22，9： | 2 |
| 3 | Perceptions of per diems in the health sector: evidence and implications显示文摘 | Vian T Miller C Themba Z | 2013 | Health Policy & Planning2013，28，3： | 1 |
| 4 | Parkinson Disease Affects Peripheral Sensory Nerves in the Pharynx显示文摘 | Liancai Mu Stanislaw Sobotka Jingming Chen Hungxi Su Ira Sanders Themba Nyirenda Charles H. Adler Holly A. Shill John N. Caviness Johan E. Samanta Lucia I. Sue Thomas G. Beach | 2013 | Journal of Neuropathology & Experimental Neurology2013，，7： | 1 |
| 5 | 外籍助教参与畜牧学研究生专业英语教学的探索与成效显示文摘专业英语是研究生的学位课程,其重要程度不言而喻;但目前研究生专业英语的师资力量不足,难以完成高效的专业英语教学任务。在专业英语的教学中外籍教师是较好的选择,这是由外籍教师自身的条件决定的;然而国内的外籍教师较缺乏,且具备专业知识背景的外籍教师少之又少,同时昂贵的聘任费用并不适用于所有高等院校。海外高年级留学生具备较高的英语水平,同时经过一段时间专业知识的学习已经具备一定的基础理论知识,可以较好地替代外籍教师来进行专业英语的教学。本院基于以上几点考虑,在畜牧学研究生专业英语中大胆尝试采用高年级海外留学生担任助教,协助主讲教师进行专业英语教学,获得了较好的效果。 | 严美姣 王悦名 Ijeoma Chirs Jiustice Matrika Rijal Oscar Themba Mdwaba 吴旭 | 2017 | 黑龙江畜牧兽医(下半月)2017，，11： | 1 |
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