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| 1 | Analysis of orthopedic surgical procedures in children with cerebral palsy显示文摘BACKGROUND Orthopedic surgery in children with cerebral palsy(CP)aims to improve function and prevent deformities.Each child’s condition in CP is unique and many covariables influence surgical decision-making including a patient's age and their functional level.Little is known about the frequency of different types of orthopedic surgery in children with CP who have varied functional levels,particularly in countries from Latin America.AIM To assess the type of orthopedic surgical procedures in relation to age and gross motor function in children with CP.METHODS This retrospective study included all children with CP(n=245)treated with elective orthopedic surgery at a Uruguayan university hospital between October 2010 and May 2016 identified from a surgical database.Eighteen children(7%)were lost to follow-up due to missing medical charts.Demographics,gross motor function classification(GMFCS),and orthopedic surgeries were obtained from the medical records of 227 children.Chi-squared tests and analysis of variance were used to assess the frequency of surgery,accounting for GMFCS levels.Mean age for soft tissue vs bone surgery was compared with the independent samples t-test.RESULTS A total of 711 surgical procedures were performed between 1998 and 2016.On average,children had 3.1 surgical procedures and the mean age at first surgery was 8.0 years.There were no significant differences in age at first surgery among GMFCS levels(P=0.47).The most common procedures were lower leg soft tissue surgery(n=189,27%),hip tenotomy(n=135,19%),and hamstring tenotomy(n=104,14%).For children with GMFCS level Ⅰ,the mean number of surgeries per child[1.8(range 1-9)]differed significantly at P<0.05 in children with GMFCS levels Ⅱ[3.2(1-12)],Ⅲ[3.2(1-8)],Ⅳ[3.3(1-13)],and Ⅴ[3.6(1-11)].Within Ⅱ,Ⅲ,Ⅳ,and Ⅴ,there was no significant difference in mean number of surgeries per child when comparing across the groups.The proportion of soft tissue surgery vs bone surgery was higher in GMFCS levels Ⅰ-Ⅲ(80%-85%)compared to levels IV(68%)and V(55%)(P<0.05).CONCLUSION The frequency of surgical procedures per child did not increase with higher GMFCS level after level Ⅰ.However,the proportion of bone surgery was higher in GMFCS levels Ⅳ-Ⅴ compared to Ⅰ-Ⅲ. | Ignacio Rehbein Viviana Teske Ignacio Pagano Alejandro Cúneo María Elena Pérez Johan von Heideken | 2020 | World Journal of Orthopedics2020，11，4： | 2 |
| 2 | Elevated sleep quality and orexin receptor mRNA in obesity-resistant rats 显示文摘 | Mavanji V Teske JA BiUington CJ | 2010 | Int J Obes (Lond)2010，34，11： | 1 |
| 3 | The elF2 kinase PERK and the integrated stress response facilitate activation of ATF6 dur- ing endoplasmic reticulum stress显示文摘 | Teske BF Wek SA Bunpo P | 2011 | Mol Biol Cell2011，22，22： | 1 |
| 4 | Subacute digoxintoxicosis in the Beagle Dog显示文摘 | Teske R H Bishop S P Righter H F | 1976 | Toxicology and Applied Phar-macology1976，35，： | 1 |
| 5 | Evolutionary relationships among ammonia-and nitrite-oxidizing bacteria 显示文摘 | Teske A Aim E Regan J M | 1994 | Journal of Bacteriology1994，176，21： | 1 |
| 6 | CD44v3-v10 reduces the profibrotic effects of TGF-betal and attenuates tubular injury in the early stage of chronic obstructive nephropathy显示文摘 | Rampanelli E Rouschop K Teske G J | 2013 | Am J Physiol Renal Physiol2013，305，10： | 1 |
| 7 | Distributed form of constraint-induced movement therapy improves functional outcome and quality of life after stroke显示文摘 | Dettmers C Teske U Hamzei F | 2005 | Arch Phys Med Rehabil2005，86，： | 1 |
| 8 | Serrsitive and rapid quantification of the cannabinoid receptor agonist naphthalen-l-yl-(1-pentylindol-3-yl) methanone (JWH- 018) in human serum by liquid chromatography-tandem mass spectrometry显示文摘 | Teske J Welier J P Fieguth A | | J Chromatogr B0，，： | 1 |
| 9 | Distributed form of constraint-induced movement therapy improves functional outcome and quality of life after stroke显示文摘 | Dettmers C Teske U Hamzer F | 2005 | Arch Phys Med Rehabil2005，86，： | 1 |
| 10 | Phylogenetic relationship of Thiomicrospira species and their identification in deep-sea hydrothermal vent samples during denaturing gradient gel electrophoresis of 16S rDNA fragments显示文摘 | Muyzer G Teske A Wirsen C O | 1995 | Archives of Microbiology1995，164，： | 1 |
| 11 | Robust absolute stability of Lur'e control systems in parameter space 显示文摘 | Tesk A Vicino A | 1991 | Automatica1991，27，1： | 1 |
| 12 | Lobaplatin as an adjuvant chemo-therapy to surgery in canine appendicular osteosarcoma:a phaseⅡevalua-tion显示文摘 | Kirpensteijn J Teske E Kik M | 2002 | Anticancer Res2002，22，5： | 1 |
| 13 | In vitro fracture behavior of ceramic and metal-ceramic restorations 显示文摘 | Smith TB Kelly JR Tesk JA | 1994 | J Prosthodont1994，3，3： | 1 |
| 14 | Microbial diversity of hydrothermal sediments in the Guaymas Basin: evidence for anaerobic methanotrophic communities显示文摘 | Teske A Hinrichs K U Edgcomb V | 2002 | Applied and Environmental Microbiology2002，68，4： | 1 |
| 15 | On the robust Popov criterion for interval Lur' e system 显示文摘 | Dahleh M Tesk A Vicino A | 1993 | IEEE Tansactions on Automatic Control1993，38，： | 1 |
| 16 | Toward a Theory of the Political Entrepreneur: Evidence from Local Government 显示文摘 | Mark Schneider Panl Teske | 1992 | American Political Science1992，86，3： | 1 |
| 17 | Microbial diver- sity of hydrothermal sediments in the Guaymas Basin: Evidence for anaerobic methanotrophic communities 显示文摘 | TESKE A HINRICHS K U EDGCOMB V | 2002 | Appl Environ Mi- crobio12002，68，： | 1 |
| 18 | Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-l-yl-( l-pentylindol-3-yl ) methanone ( JWH- 018) in human serum by liquid chromatography-tandem mass spectrometry 显示文摘 | Teske J Weller J P Fieguth A | 2010 | J Chromatogr B2010，878，： | 1 |
| 19 | TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury显示文摘 | Pulskens WP Rampanelli E Teske G J | | 0，，08： | 1 |
| 20 | Biosphere frontiers of subsurface life in the sedimented hydrothermal system of Guaymas Basin显示文摘 | Teske A Callaghan A V Larowe D E | 2014 | Frontiers in Microbiology2014，5，： | 1 |
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