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| 1 | Is the neutrophil to lymphocyte ratio associated with liver fibrosis in patients with chronic hepatitis B?显示文摘AIM: To determine the association between the neutrophil to lymphocyte(N/L) ratio and the degree of liver fibrosis in patients with chronic hepatitis B(CHB) infection. METHODS: Between December 2011 and February 2013, 129 consecutive CHB patients who were admitted to the study hospitals for histological evaluation of chronic hepatitis B-related liver fibrosis were included in this retrospective study. The patients were divided into two groups based on the fibrosis score: individuals with a fibrosis score of F0 or F1 were included in the 'no/minimal liver fibrosis' group, whereas patients with a fibrosis score of F2, F3, or F4 were included in the 'advanced liver fibrosis' group. The Statistical Package for Social Sciences 18.0 for Windows was used to analyze the data. A P value of < 0.05 was accepted as statistically significant.RESULTS: Three experienced and blinded pathologists evaluated the fibrotic status and inflammatory activity of 129 liver biopsy samples from the CHB patients. Following histopathological examination, the 'no/minimal fibrosis' group included 79 individuals, while the 'advanced fibrosis' group included 50 individuals. Mean(N/L) ratio levels were notably lower in patients with advanced fibrosis when compared with patients with no/minimal fibrosis. The mean value of the aspartate aminotransferase-platelet ratio index was markedly higher in cases with advanced fibrosis compared to those with no/minimal fibrosis.CONCLUSION: Reduced levels of the peripheral blood N/L ratio were found to give high sensitivity, specificity and predictive values in CHB patients with significant fibrosis. The prominent finding of our research suggests that the N/L ratio can be used as a novel noninvasive marker of fibrosis in patients with CHB. | Murat Kekilli Alpaslan Tanoglu Yusuf Serdar Sakin Mevlut Kurt Serkan Ocal Sait Bagci | 2015 | World Journal of Gastroenterology2015，21，18： | 15 |
| 2 | Clinical importance of serum procalcitonin in ulcerative colitis patients显示文摘We have read with interest the recently published article entitled 'Clinical significance of serum procalcitonin in patients with ulcerative colitis' by Koido et al. They aimed to investigate the association of procalcitonin with ulcerative colitis(UC) activity. They concluded that elevated procalcitonin levels were significantly correlated with UC activity. We would like to thank the authors for their comprehensive contribution. | Ergenekon Karagoz Alpaslan Tanoglu | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 3 | Clinical usefulness ofmean platelet volume and red blood cell distribution width to plate- let ratio for predicting the severity of hepatic fibrosis in chronic hepatitis B virus patients 显示文摘 | Karagoz El Ulcay A Tanoglu A | 2014 | Eur J Gastroenterol Hepatol2014，26，12： | 1 |
| 4 | Mechanical properties and microstructural evaluation of AA5013 aluminum alloy treated in the semi-solid state by SIMA process 显示文摘 | SAKLAKOGLU N SAKLAKOGLU I E TANOGLU M OZTAS O CUBUKCUOGLU O | 2004 | J Mater Process Technol2004，148，1： | 1 |
| 5 | Development and mechanicalbehavior of FML/aluminium foam sandwiches 显示文摘 | Basturk S B Tanoglu M | 2013 | AppliedComposite Materials2013，20，5： | 1 |
| 6 | Critical aspects related to processing of carbon nanotube/unsaturated thermoset polyester nanocomposites显示文摘 | Tugrul Seyhan Florian H Gojny Metin Tanoglu | 2007 | Europoan Polymer Journal2007，43，2： | 1 |
| 7 | 显示文摘 | Elcin Kaya Metin Tanoglu Salih Okur | 2008 | Journal of Applied Polymer Science2008，109，2： | 1 |
| 8 | Mechanical properties and microstructural evaluation of AA5013 aluminum alloy treated in the semi-solid state by SIMA process 显示文摘 | SAKLAKOGLU N SAKLAKOGLU I E TANOGLU M OZTAS O CUBUKCUOGLU O | 2004 | J Mater Proc Technol2004，148，： | 1 |
| 9 | Morphosynthesis of CaC03 at Different Reaction Temperatures and the Effects of PDDA, CTAB, and EDTA on the Particle Morphology and Polymorph Stability显示文摘 | Altay E Shahwan T Tanoglu M | 2007 | Powder Technology2007，178，： | 1 |
| 10 | Erythropoietin exerts neuroprotection after acute spinal cord injury in rats:effect on lipid peroxidation and early ultrastructural findings显示文摘 | Kap tanoglu E Solaroglu I Okutan O | | 0，，02： | 1 |
| 11 | Effects of thermoplastic preforming binder on the properties of S2-glass fabric reinforced epoxy composites 显示文摘 | Tanoglu Metin Robert S Heider D | 2001 | International Journal of Adhesion & Adhesives2001，21，： | 1 |
| 12 | Effectiveness of interleukin-1 receptor antagonist (Anakinra) on cerulein- induced experimental acute pancreatitis in rats 显示文摘 | Kaplan M Yazgan Y Tanoglu A | 2014 | Scand J Gastroenterol2014，49，9： | 1 |
| 13 | Investigating the effects of a polyester preforming binder on the mechanical and ballistic performance of E glass fiber reinforced polyester composites 显示文摘 | Tanoglu Metin Seyhan A Tugrul | 2003 | International Journal of Adhesion & Adhesives2003，23，1： | 1 |
| 14 | Compressive mechanical behaviour of E-glass/polyester composite laminates tailored with a thermoplastic preforming binder 显示文摘 | Tanoglu Metin Seyhan A Tugrul | 2003 | Materials Science and Engineering A2003，363，12： | 1 |
| 15 | Effectiveness of interleukin - 1 receptor antagonist ( Anakinra ) on cerulein - induced experimental acute pancreatitis in rats 显示文摘 | KAPLAN M YAZGAN Y TANOGLU A | 2014 | Scand J Gastroenterol2014，499，： | 1 |
| 16 | A new technique to characterize the fiber/matrix interphase properties under high strain rates显示文摘 | Tanoglu M McKnight S H Pahnese G R | 2000 | Composites: Part A2000，31，10： | 1 |
| 17 | Morphosynthesis of CaCO3 at different reaction temperatures and the effects of PDDA,CTAB,and EDTA on the particle morphologyand polymorph stability显示文摘 | Altay E Shahwan T Tanoglu M | | 0，，03： | 1 |
| 18 | Morphosyntbesis of CaCO3 at Different Reaction Temperatures and the Effects of PDDA,CTAB,And EDTA on the Particle Morphology and Polymorph Stability 显示文摘 | Altay E Shahwan T Tanoglu M | 2007 | Powder Technology2007，178，3： | 1 |
| 19 | Mechanical properties and microstructural evaluation of A5013aluminum alloy treated in the semi-solid state by SIMA process显示文摘 | SAKLAKOGLU N SAKLAKOGLUA E I TANOGLU M | 2004 | Journal of Materials Processing Technology2004，148，： | 1 |
| 20 | Mode I and mode II frac- ture toughness of E-glass non-crimp fabric/carbon nanotube (CNT) modified polymer based composites显示文摘 | Seyhan A T Tanoglu M Schulte K | 2008 | Engineering Fracture Mechanics2008，75，18： | 1 |
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