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108篇 您的检索式：作者名="Talwar P"

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	题名	作者	年代	出处	被引量
1	Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model显示文摘AIM To investigate the therapeutic potential of two recombinant proteins, Survivin and luteinizing hormone-releasing hormone (LHRH) fusion protein [LHRH(6 leu)-LTB] for immunotherapy of breast cancer.METHODS Murine 4 T-1 breast cancer model was used to evaluate the efficacy of recombinant proteins in vivo. Twenty four Balb/c mice were divided into 4 groups of 6 mice each. Recombinant Survivin and LHRH fusion protein, alone or in combination, were administered along with immunomodulator Mycobacterium indicus pranii (MIP) in Balb/c mice. Unimmunized or control group mice were administered with phosphate buffer saline. Each group was then challenged with syngeneic 4 T-1 cells to induce the growth of breast tumor. Tumor growth was monitored to evaluate the efficacy of immune-response in preventing the growth of cancer cells.RESULTS Preventive immunization with 20 μg recombinant Survivin and MIP was effective in suppressing growth of 4 T-1 mouse model of breast cancer (P = 0.04) but 50 μg dose was ineffective in suppressing tumor growth. However, combination of Survivin and LHRH fusion protein was more effective in suppressing tumor growth (P = 0.02) as well as metastasis in vivo in comparison to LHRH fusion protein as vaccine antigen alone.CONCLUSION Recombinant Survivin and MIP suppress tumor growth significantly. Combining LHRH fusion protein with Survivin and MIP enhances tumor suppressive effects marginally which provides evidence for recombinant Survivin and LHRH fusion protein as candidates for translating the combination cancer immunotherapy approaches.	Himani Garg Rohit Singh Hada Jagdish C Gupta G P Talwar Shweta Dubey	2018	World Journal of Clinical Oncology2018，9，8：	2
2	Biodegradable delivery system for a birth control vaccine:immunogenicity studies in rats and monkeys显示文摘	Singh M Singh O Talwar G P	1995	Pharm Res1995，12，：	1
3	Oscillating positive expiratory pressure on respiratory resistance in chronic obstructive pulmonary disease with a small amount of secretion:a randomized clinical trial显示文摘	Gastaldi AC Paredi P Talwar A	2015	Medicine(Baltimore)2015，94，42：	1
4	Induced termination of pregnancy by purified extracts of Azadirachta India (Neem): Mechanisms involved 显示文摘	Talwar G P Shah S Mukherjee S	1997	Am J Reprod Immunol1997，37，：	1
5	Comparative study of band-structure calculations for type-Ⅱ InAs/Inx Gal-xSb strained-layer superlattices显示文摘	Talwar D N Loehr J P Jogai B		0，，：	1
6	Profile of plasma N-terminal proBNP following acute myocardial infarction , correlation with left ventricular systolic dysfunction 显示文摘	Talwar S Squire I B Downie P F	2000	Eur Heart J2000，21，18：	1
7	Genetic variability in estrogen disposition : potential clinical implications for neuropsychiatric dis- orders显示文摘	Grover S Talwar P Baghel R	2010	AmJ Med Genet Part B: Neuropsychiatric Genetics2010，153，：	1
8	The anomalous origin of the branch pulmonary artery from the ascending aorta显示文摘	Garg P Talwar S Kothari SS		0，，01：	1
9	A dramatic effect of stereochemistry on the plant growth activity of the cadinane group of terpenoids显示文摘	Kalsi P S Talwar K K	1981	Phytochemistry1981，20，：	1
10	Plant immunomodu- lators for termination of unwanted pregnancy and for contracep- tion and reproductive health 显示文摘	Talwar G P Raghuvanshi P Misra R	1997	Immunol Cell Biol1997，75，2：	1
11	A Molecu- lar Web: Endoplasmic Reticulum Stress, Inflammation, and Oxi- dative Stress 显示文摘	Chaudhari N Talwar P Parimisetty A	2014	Frontiers in Cellular Neuroscience2014，8，：	1
12	A vaccine that prevents pregnancy in women 显示文摘	Talwar G P Singh O Pal R	1994	Proc Natl Acad Sci USA1994，91，18：	1
13	Profile of plasma N-terminal proBNP following acute myocardial infarction; correlation with left ventricular systolic dysfunction 显示文摘	Talwar S Squire I B Downie P F	2000	Eur Heart J2000，21，：	1
14	A sesquiterpenoid with plant growth regulatory activity from Saussurea lappa 显示文摘	Talwar K K Singh I P Kalsi P S	1992	Phytochemistry1992，31，1：	1
15	Web Mining in Soft Computing Framework:Relevance,State of the Art and Future Directions显示文摘	Pal S K Talwar V Mitra P	2002	IEEE Transactions on Neural Networks2002，13，5：	1
16	Orange-red luminescence from Cu doped CdS nanophosphor prepared using mixed Langmuir-Blodgett multilayers 显示文摘	Mandal P Talwar S Major S	2008	The Journal of Chemical Physics2008，128，11：	1
17	Plasma N terminal pro-brain natriuretic peptide and cardiotro- phin 1 are raised in unstable angina显示文摘	TALWAR SQUIRE I B DOWNIE P F	2000	Heart2000，84，：	1
18	No 'power' struggles: Coordimated multi-level power management for the data center 显示文摘	Raghavendra R Ranganathan P Talwar V	2008	SIGARCH: Computer Architecture News2008，36，1：	1
19	Enzyme-linked immunosorbent assay and immunoblot study in Takayasu's arteritis patients显示文摘	Dhingra R Chopra P Talwar KK	1997	Indian Heart J1997，50，：	1
20	Plasma N-terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina 显示文摘	TALWAR S SQUIRE I B DOWNIE P F	2000	Heart2000，84，：	1

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