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35篇 您的检索式：作者名="TSELEPIS A"

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	题名	作者	年代	出处	被引量
1	Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma显示文摘AIM: To characterise expression of known E-cadherin repressors; Snail, Slug and Twist in the development of esophageal adenocarcinoma. METHODS: E-cadherin, Slug, Snail and Twist mRNA expression in Barrett's metaplasia and esophageal adenocarcinoma specimens was examined by real-time reverse transcription-polymerase chain reaction (RT-PCR). Semi-quantitative immunohistochemistry was used to examine cellular localisation and protein levels. The effect of Slug on epithelial mesenchymal transition (EMT) markers was examined by transfection of Slug into an adenocarcinoma line OE33.RESULTS: Cellular localisation of Slug in Barrett's metaplasia was largely cytoplasmic whilst in adenocarcinoma it was nuclear. Semi-quantitative analysis indicated that Slug was more abundant in adenocarcinoma compared to matched Barrett's metaplastic specimens. Snail and Twist were expressed in adenocarcinoma but were cytoplasmic in location and not induced compared to Barrett's mucosa. These observations were supported by mRNA studies where only Slug mRNA was shown to be over-expressed in adenocarcinoma and inversely correlated to E-cadherin expression. Overexpression of Slug in OE33 mediated E-cadherin repression and induced the mesenchymal markers vimentin and fibronectin.CONCLUSION: Progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing.	Paras Jethwa Mushal Naqvi Robert G Hardy Neil A Hotchin Sally Roberts Robert Spychal Chris Tselepis	2008	World Journal of Gastroenterology2008，14，7：	24
2	PLateler - asmciated and secreted PAF aeetylhydrnlase activity in patients with stable angina: sequen tial changes of the enzyme activity after angioplasty 显示文摘	Goudevenos J TseLepis A D Vini M P	2001	Eur JC Linic Invest2001，31，1：	1
3	Trimetazidine protects lowdensity lipoproteins from oxidation and cultured cells exposed to H2O2 from DNA damage显示文摘	Tselepis A Doulias P Lourida E	2001	Free Radic Biol Med2001，30，12：	1
4	Lipid peroxida- tion and the use of emulsified propofol in laparoseopic surgery 显示文摘	Manataki A D Tselepis A D Glantzounis G K	2001	Surg Endosc2001，15，9：	1
5	The effects of rosuvastatin alone or in combination with fenofibrate or omega 3 fatty acids on inflammation and oxidative stress in patients with mixed dyslipidemia显示文摘	Aris P Agouridis Vasilis Tsimihodimos Theodosios D Filippatos Andromachi A Dimitriou Costantinos C Tellis Moses S Elisaf Dimitri P Mikhailidis Alexandros D Tselepis	2011	Expert Opinion on Pharmacotherapy2011，，17：	1
6	Apolipoprotein(a) phenotypes and lipoprotein(a) concentrations in patients with renal failure显示文摘	Milionis HJ Elisaf MS Tselepis A	1999	Am J Kidney Dis1999，33，6：	1
7	Smoking induces lipopmtein-assoeiated phospholipnse A2 in cardi-ovascular disease free adults:the AT CA Study显示文摘	Alexandres D Tselepis A Demosthenes B	2010	Ath-erosclerosis2010，16，2：	1
8	Catalytic inhibition of eukaryotic topoisomerases I and II by flavonol glycosides extracted from Viciafaba and Lotus edulis显示文摘	Tselepi M Papachristou E Emmanouilidi A	2011	Journal of Natural Products2011，74，11：	1
9	Effects of ezetimibe,either alone or in combination with atorvastatin,on serum visfatin levels; a pilot study显示文摘	Derdemezis C Filippatos T Tselepis A	2008	Expert Opin Pharmacother2008，9，11：	1
10	laparoseopic surgery-induced changes in oxidative stress markers in human plasma显示文摘	Glantzounis G K Tselepis A D	2001	Suegical endoscopy2001，15，11：	1
11	Effects of ezetimibe, either alone or in combination with atorwslatm, on serum visfatin levels: a pilot study]显示文摘	crdemezis C Filippatos T Tselepis A el	2008	Expert in Pharma tother2008，9，18：	1
12	Therapeuticmodulation of lipoprotein-associated phospholipase A2 (Lp-PLA2)显示文摘	TSELEPIS A F RIZZO M GOUDEVENOS i A	2011	Curr Pharm Des2011，17，33：	1
13	Recent advances on the an- tiatherogenic effects of HDL-derived proteins and mimetic peptides 显示文摘	Petraki M P Mantani P T Tselepis A D	2009	Curr Pharm Des2009，15，27：	1
14	Influence of high density lipoprotein and paraoxonase 1 on platelet reactivity in patients with acute coronary syndromes receiving clopidogrel therapy显示文摘	Tselepis A D Tsoumani M E Kalantzi K l etal	2011	J Thromb Haemost2011，9，12：	1
15	Trimetazidine protects low density lipoproteins from oxidation and cultured cells exposed to H (2)O( 2 ) from DNA damage 显示文摘	Tselepis A Doulias P Lourida E	2001	Frec Radic Boil Med2001，30，12：	1
16	New insights into the roleof lipoprotein(a) - associated lipoprotein - associated phospholipaseA2 in atherosclerosis and cardiovascular disease 显示文摘	Tsimikas S Tsironis L D Tselepis A D	2007	ArteriosclerThromb Vase Biol2007，27，10：	1
17	Laparoscopic surgery-induced changes in oxidative stress markers in human plasma显示文摘	Glantzounis G K Tselepis A D Tambaki A P	2001	Surg Endosc2001，15，11：	1
18	Apolipoprotein(a) phenotypes and lipoprotein(a) concentration in patients with renal failure 显示文摘	MILLIONIS H ELISAF M TSELEPIS A	1999	Am J Kidney Dis1999，34，6：	1
19	Trimetazidine protects lowdensity lipoproteins from oxidation and cultured cells exposed to H (2) O(2) from DNA damage显示文摘	Tselepis A Doulias P Lourida E	2001	Free Radic Biol Med2001，30，12：	1
20	Lipid peroxidation and the use of emulsified propofol in laparoscopie surgery显示文摘	MANATAKI A D TSELEPIS A D GLANTZOUNIS G K	2001	Surg Endosc2001，15，3：	1

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