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| 1 | Atomic force microscopy and photon correlation spectroscopy: two techniques for rapid characterization of liposomes显示文摘 | RUOZI B TOSI G FOMI F | 2005 | European Journal of Pharmaceutical Sciences2005，25，1： | 1 |
| 2 | Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy显示文摘Diabetic retinopathy(DR)affects approximately one-third of diabetic patients and,if left untreated,progresses to proliferative DR(PDR)with associated vitreous hemorrhage,retinal detachment,iris neovascularization,glaucoma and irreversible blindness.In vitreous samples of human patients with PDR,we found elevated levels of hypoxia inducible factor 1 alpha(HIF1α).HIFs are transcription factors that promote hypoxia adaptation and have important functional roles in a wide range of ischemic and inflammatory diseases.To recreate the human PDR phenotype for a preclinical animal model,we generated a mouse with neuroretinal-specific loss of the von Hippel Lindau tumor suppressor protein,a protein that targets HIF1αfor ubiquitination.We found that the neuroretinal cells in these mice overexpressed HIF1αand developed severe,irreversible ischemic retinopathy that has features of human PDR.Rapid progression of retinopathy in these mutant mice should facilitate the evaluation of therapeutic agents for ischemic and inflammatory blinding disorders.In addition,this model system can be used to manipulate the modulation of the hypoxia signaling pathways,for the treatment of non-ocular ischemic and inflammatory disorders. | Katherine J Wert Vinit B Mahajan Lijuan Zhang Yuanqing Yan Yao Li Joaquin Tosi Chun Wei Hsu Takayuki Nagasaki Kerstin M Janisch Maria B Grant MaryAnn Mahajan Alexander G Bassuk Stephen H Tsang | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 1 |
| 3 | A method for the pharmacognostic study of aloe species using fluorescence microscopy显示文摘 | BRUNI A TOSI B | 1982 | Int J Crude Drug Res1982，20，3： | 1 |
| 4 | Atomic force microscopy and photon correlation spectroscopy: Two techniques for rapid characterization of liposomes 显示文摘 | Ruosi B Tosi G Fomi F | 2005 | European Journal of Pharmaceutical Sciences2005，25，1： | 1 |
| 5 | Ambroxol for prophylaxis and treatment of broncho-pulmonary complications after chest surgery显示文摘 | ROMANINI B M SANDRI M G TOSI M | 1996 | Int J Clin Res1996，2，3： | 1 |
| 6 | Atomic force microscopy and photon correlation spectroscopy:two techniques for rapid characterization of liposomes显示文摘 | Ruozi B Tosi G Forni F | 2005 | European Journal of Pharmaceutical Science2005，25，1： | 1 |
| 7 | Antifungal activity of Tagetes patulaextracts on some phytopathogenic fungi:ultrastructural evidence on Pythium ultimum显示文摘 | Mares D Tosi B Andreotti E | 2004 | Microbiological Research2004，159，3： | 1 |
| 8 | Atomic force microscopy and photon correlation spectroscopy: two techniques for rapid characterization of liposornes显示文摘 | RUOZI B TOSI G FORNI F | 2005 | European Journal of Pharmaceutical Sciences2005，25，1： | 1 |
| 9 | Application of atomic force microscopy to characterize liposomes as drug and gene carriers显示文摘 | RUOZI B TOSI G LEO E | 2007 | Talanta2007，73，1： | 1 |
| 10 | Discrepancy between cell culture and animal studies 显示文摘 | TOSI K M DAI Q ALMAN B A | 2013 | Ace Chem Res2013，46，： | 1 |
| 11 | Morphology and secretion of glandular trichomes in tamus communis显示文摘 | Bruni A Tosi B Modenesi P | 1987 | Nordic Journal of Botany1987，7，： | 1 |
| 12 | Characterization of in- nate lymphoid cells in human skin and blood demonstrates in crease of NKp44+ ILC3 in psoriasis显示文摘 | Villanova F Flutter B Tosi I | 2014 | J Invest Dermatol2014，134，4： | 1 |
| 13 | Antifungal activity of Tagetes patula extracts on some phytopathogenic fungi: ultrastructural evidence on Pythium ultimum显示文摘 | MARES D TOSI B POLl F | 2004 | Microbiological Research2004，159，： | 1 |
| 14 | The decoupling of CEO pay and performance:an agency theory perspective 显示文摘 | TOSI H L GOMEZ-MEJIA L B | 1989 | Administrative Science Quarterly1989，34，： | 1 |
| 15 | Atomic force microscopy and photon correlation spectroscopy:two techniques for rapid characterization of liposomes 显示文摘 | Ruozi B G Tosi | 2005 | Eur J Pharm Sci2005，25，1： | 1 |
| 16 | Antimicrobial actvity of some commercial extracts of propolis prepared with different solvents显示文摘 | Tosi B Donini A Romagnoli C | 1996 | Phytother Res 19961996，，： | 1 |
| 17 | Flow pat- terns of an air-water mixture at the exit of a micro T- junction 显示文摘 | PUCCETYI G TOSI M PULVIRENTI B | 2015 | Experimental Thermal and Fluid Science2015，67，： | 1 |
| 18 | Clearance of minimal residual disease after allogeneic stem cell transplantation and the prediction of the clinical outcome of adult patients with high-risk acute lymphoblastic leukemia显示文摘 | Spinelli O Peruta B Tosi M | | 0，，： | 1 |
| 19 | Antifungal activity of Tagetes patula extracts on some phytopathogenic lungi: ultrastructural evidence on Pythium ultimum 显示文摘 | Mares D Tosi B Andreotti E | 2004 | Microbiological Research2004，159，3： | 1 |
| 20 | fungi isolated from Antarctic mosses显示文摘 | Tosi S Casado B Gerdol R | 2002 | Polar Biology2002，25，4： | 1 |
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