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| 1 | Prospective validation of %p2PSA and the Prostate Health Index, in prostate cancer detection in initial prostate biopsies of Asian men, with total PSA 4-10 ng ml-1显示文摘尽管有它为屏蔽的前列腺癌症的普遍使用,低特性使 PSA 成为非最优的 biomarker,特别在 4-10 ng ml 1 的诊断灰色的地区。假积极与伴随的病态导致不必要的活体检视。这在与在 4.0 和 10 ng ml 1 之间的全部的 PSA 介绍的亚洲人是 % p2PSA 和前列腺健康索引(PHI ) 的第一未来的确认研究。我们学习了在 50 和 75 岁之间的 157 个亚洲人,与每直肠的前列腺考试的正常,经历他们的第一前列腺活体检视,用一个标准化活体检视协议,为 4-10 ng ml 1 的 PSA 层次。(19.1%) 三十被发现在活体检视上有前列腺癌症。有或没有前列腺癌症的病人之间的统计上重要的差别被作出对有利的裁决全部的 PSA, p2PSA, % p2PSA,和 PHI。在为全部的 PSA, % fPSA, % p2PSA,和 PHI 操作典型曲线的接收装置的曲线下面的区域分别地是 0.479, 0.420, 0.695,和 0.794。PHI 最好预言 prostatic 活体检视结果。在 90% 的敏感, PHI 的特性(95% CI ) 是 58.3% ,多于在 17.3% 点使全部的 PSA 的特性增加两倍,潜在地避免 77 (49%) 不必要的活体检视。类似于研究在主要白种人人口,我们有希望地证明了 % p2PSA 和 PHI 极大地超过总数并且释放总计 PSA 比率,在前列腺癌症的察觉起初活体检视。更高的 PHI 层次也对应于增加检测 GS 7 癌症的风险。我们验证了 PHI 的使用与在 4 和 10 ng ml 1 之间的浆液 PSA 在亚洲人关于前列腺活体检视帮助决策。 | Lincoln GL Tan Yung Khan Tan Bee Choo Tai Karen ML Tan Vineet Gauhar Ho Yee Tiong Robert CW Hawkins Thomas P Thamboo Felicia SK Hong Edmund Chiong | 2017 | Asian Journal of Andrology2017，19，3： | 13 |
| 2 | Halitosis:the multidisciplinary approach显示文摘Halitosis,bad breath or oral malodour are all synonyms for the same pathology. Halitosis has a large social and economic impact. For the majority of patients suffering from bad breath,it causes embarrassment and affects their social communication and life. Moreover,halitosis can be indicative of underlying diseases. Only a limited number of scientific publications were presented in this field until 1995. Ever since,a large amount of research is published,often with lack of evidence. In general,intraoral conditions,like insufficient dental hygiene,periodontitis or tongue coating are considered to be the most important cause (85%) for halitosis. Therefore,dentists and periodontologists are the first-line professionals to be confronted with this problem. They should be well aware of the origin,the detection and especially of the treatment of this pathology. In addition,ear-nose-throat-associated (10%) or gastrointestinal/ endocrinological (5%) disorders may contribute to the problem. In the case of halitophobia,psychiatrical or psychological problems may be present. Bad breath needs a multidisciplinary team approach:dentists,periodontologists,specialists in family medicine,ear-nose-throat surgeons,internal medicine and psychiatry need to be updated in this field,which still is surrounded by a large taboo. Multidisciplinary bad breath clinics offer the best environment to examine and treat this pathology that affects around 25% of the whole population. This article describes the origin,detection and treatment of halitosis,regarded from the different etiological origins. | Curd ML Bollen Thomas Beikler | 2012 | International Journal of Oral Science2012，4，2： | 7 |
| 3 | Ileal inflammatory fibroid polyp causing chronic ileocolic intussusception and mimicking cecal carcinoma显示文摘Inflammatory fibroid polyp(IFP) is a rare,idiopathic pseudotumorous lesion of the gastrointestinal tract.While mostly reported as solitary gastric lesions,multiple cases of small bowel IFPs are also reported.It is a documented cause of intussusception in adults.In the case reports of ileal inflammatory fibroid polyps with intussusception,an emergent presentation with small bowel obstruction has been most often described.Here we depict a case of ileal inflammatory fibroid polyp presenting with chronic intermittent ileocolic intussusception,anemia and weight loss with an endoscopic appearance mimicking necrotic cecal carcinoma. | Naveen Gara John S Falzarano Whitney ML Limm Thomas S Namiki Laurie KS Tom | 2009 | World Journal of Gastrointestinal Oncology2009，1，1： | 3 |
| 4 | Pulmonary Cryptococcosis: CT Findings in Immunocompetent Patients 显示文摘 | Rebecca ML Thomas EH Hassan FN | 2005 | Radiology2005，236，1： | 1 |
| 5 | Time - De- pendent Changes in Matrix Metalloproteinase acti0itg and expression during the progression of congestive heart failure: relation to ventricular and myocyte function显示文摘 | Spinale FG Coker ML Thomas CV | 1998 | Circ Res1998，82，4： | 1 |
| 6 | Sevoflu- rane sedation in infants undergoingMRI: a preliminary report 显示文摘 | Sury MR Harker H Thomas ML | 2005 | Paediatr Anaesth2005，15，1： | 1 |
| 7 | Caudal additives in children-solutions or problems?显示文摘 | De Beer DA Thomas ML | 2003 | Br J Anaesth2003，90，： | 1 |
| 8 | Case-based teaching and learning experience显示文摘 | Thomas MD O'Connor FW Albert ML | 2001 | Issues Ment Health Nurs2001，22，5： | 1 |
| 9 | Increased matrix metalloproteinases activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy显示文摘 | Thomas CV Coker ML Zellner JL | 1998 | Circulation1998，97，17： | 1 |
| 10 | Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy显示文摘 | Coker ML Zellner JL | 1998 | Circulation1998，97，17： | 1 |
| 11 | Time-dependent changes in matrix metalloproteinase activity and expression during the progression of congestive heart failure 显示文摘 | Spinale FG Coker ML Thomas CV | 1998 | Circ Res1998，82，： | 1 |
| 12 | Summary of the 2008 BTS/ SIGN British guideline on the management of asthma 显示文摘 | Levy ML Thomas M Small I | 2009 | Prim Care Respir J2009，181，： | 1 |
| 13 | Myocardial matrix metalloproteinase activity and abundance with congestive heart failure显示文摘 | Thomas CV Clair MJ | 1998 | Am J Physiol1998，274，52： | 1 |
| 14 | Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy显示文摘 | Thomas CV Coker ML Zellner JL | 1998 | Circulation1998，97，： | 1 |
| 15 | Incorporating standardized patients into a psychosocial nurse practitioner program显示文摘 | O'Connor FW Albert ML Thomas MD | 1999 | Archives of Psychiatric Nursing1999，13，5： | 1 |
| 16 | The iliac compression syndrome显示文摘 | THOMAS ML | 1965 | Br J Surg1965，52，10： | 1 |
| 17 | Increased matrix meatalloproteinase activity and selective upmgulation in LV mycatdium from patients with end-stage dilated cantiomyopathy显示文摘 | Thomas CV Coker ML Zellner JL | 1998 | Circulation1998，97，17： | 1 |
| 18 | Case-based teaching and learning experience 显示文摘 | Thomas MD OConnor FW Albert ML | 2001 | Issues Ment Health Nurs2001，22，5： | 1 |
| 19 | Case-based teaching and learning experiences显示文摘 | Thomas MD O'Connor FW Albert ML | 2001 | Mental Health Nursing2001，22，1： | 1 |
| 20 | lschemic Colitis显示文摘 | Marston A Pheils MT Thomas ML | 1996 | Gut1996，7，： | 1 |
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