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	题名	作者	年代	出处	被引量
1	Therapeutic proteasome inhibition in experimental acute pancreatitis显示文摘AIM: To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis.METHODS: Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 μg/kg) and the proteasome inhibitor MG132 (10 mg/kg ip) was administered 30 min after the second CCK injection. Animals were sacrificed 4 h after the first injection of CCK.RESULTS: Administering the proteasome inhibitor MG132 (at a dose of 10 mg/kg, ip) 90 min after the onset of pancreatic inflammation induced the expression of cell-protective 72 kDa heat shock protein (HSP72) and decreased DNA-binding of nuclear factor-kB (NF-kB). Furthermore MG132 treatment resulted in milder inflammatory response and cellular damage, as revealed by improved laboratory and histological parameters of pancreatitis and associated oxidative stress.CONCLUSION: Our findings suggest that proteasome inhibition might be beneficial not only for the prevention, but also for the therapy of acute pancreatitis.	Tamás Letoha Liliána Z Fehér László Pecze Csaba Somlai Ilona Varga József Kaszaki Gábor Tóth Csaba Vizler László Tiszlavicz Tamás Takács	2007	World Journal of Gastroenterology2007，13，33：	5
2	神经连接蛋白-3缺乏可阻止高分级神经胶质瘤生长显示文摘在一项新的研究中,来自美国国家卫生研究院、斯坦福大学、达纳法伯癌症研究所和哈佛医学院的研究人员发现某些侵袭性脑瘤的生长能够通过切断它们获取大脑中神经细胞产生的一种信号分子加以阻止.这些研究人员发现当这种被称作神经连接蛋白-3(neuroligin-3,NLGN3)的信号分子缺乏时,或者当利用药物干扰这种信号分子时,人高分级神经胶质瘤不能够在小鼠大脑中扩散.	Venkatesh H S Tam L T Woo P J	2017	临床误诊误治2017，30，11：	3
3	Barefoot rnn- ning:An evaluation of current hypothesis future research and clinical applications显示文摘	TAM N WILSON J L A NOAKES T D	2014	Br J Sports Med2014，48，：	1
4	Prospective randomized trial of argon plasma coagulation ablation versus endoscopic surveillance of Barrett's esophagus in patients treated with antisecretory medication显示文摘	BRIGHT T WATSON D TAM W	2009	Dig Dis Sci2009，54，12：	1
5	Nitrogen use efficiency characteristics of Andigena and diploid potato selections 显示文摘	Zebarth B J Tam T R Jong H de	2008	American Journal of Potato Research2008，85，：	1
6	Improvement in cavitation erosion resistance of a copper-based propeller alloy by laser surface melting显示文摘	Tam K F Cheng F T Man H C	2004	Surface and Coatings Technology2004，182，2：	1
7	Comparative Study of Artificial Neural Networks and Multiple Regression Analysis for Predicting Hoisting Times of Tower Cranes显示文摘	Arthur W T Leung C M Tam D K Liu	2000	Building and Environment2000，36，4：	1
8	Properties of concrete made with crushed concrete as coarse aggregate显示文摘	Ravindrarajah R S Tam C T	1985	Magazine ofConcrete Research1985，37，130：	1
9	Distinct EMT programs control normal mammary stem cells and tumour-initiating cells 显示文摘	YE X TAM WL SHIBUE T	2015	Nature2015，525，7568：	1
10	Stability analysis of non-time referenced Internetbased telerobotic systems 显示文摘	Tam T J	2000	Robotics and Autonomous System2000，32，2：	1
11	Recycled concrete as fine and coarse aggregates in eoncrete显示文摘	RAVINDRARAJAH R TAM C T	1987	Magazine of Concrete Research1987，39，141：	1
12	Capsaicin-sensitive local sensory innervation is involved in pacing-induced preconditioning in rat hearts: role of nitric oxide and CGRP?显示文摘	P. Ferdinandy Tamás Csont Csaba Csonka Marianna T?r?k Mária Dux József Németh László I. Horváth László Dux Zoltán Szilvássy Gábor Jancsó	1997	Naunyn - Schmiedeberg’s Archives of Pharmacology1997，，3：	1
13	Products of ozone-initiated chemistry in a simulated aircraft environment显示文摘	Wisthaler A Tamás G Wyon D P Strφm-Tejsen P Space D Beauchamp J Hansel A M(a)rk T D Weschler C J		0，，13：	1
14	A case study on fuel oil contamination in a mangrove swamp in Hong Kong 显示文摘	TAM N F Y WONG T W Y WONG Y S	2005	Marine Pollution Bulletin2005，51，812：	1
15	Developing a risk assess- ment model for Construction Safety显示文摘	FUNG I W H TAM V W Y IX) T Y	2010	International Journal of Pro- iect Management2010，28，6：	1
16	Acoustic emission characteristics of mortar under compression 显示文摘	WENG C C TAM M T LIN G C	1992	Cement and Concrete Research1992，22，4：	1
17	Non-structural fuzzy decision support system for evaluation of construction safety management system 显示文摘	TAM C M TONG T K L CHIU G C V	2002	International Journal of Project Manage- ment2002，20，4：	1
18	A Carbonation Prediction Model for Accelerated Carbonation Testing o{ Concrete显示文摘	Loo Y H Chin M S Tam C T	1994	Magaz Concr Res1994，88，4：	1
19	显示文摘	Tam T M	1986	J Electrochem Soc1986，133，：	1
20	Recycled concrete as fine and coarse aggregate in concrete 显示文摘	RAVINDRARAJAH R TAM C T	1987	Magazine of ConcreteResearch1987，39，141：	1

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