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| 1 | The prospects of regenerative medicine combined with rehabilitative approaches for chronic spinal cord injury animal models显示文摘Regenerative medicine has opened a window for functional recovery in acute-to-subacute phase spinal cord injury(SCI).By contrast,there are still only a few studies have focused on the treatment of the chronically injured spinal cord,in which cell-based regenerative medicine seems less effective.Since the majority of SCI patients are in the chronic phase,representing a major challenge for the clinical application of cellbased regenerative medicine.Although combined therapies for the treatment of chronic SCI have attracted attention of researchers and its potential importance is also widely recognized,there had been very few studies involving rehabilitative treatments to date.In a recent study,we have demonstrated for the first time that treadmill training combined with cell transplantation significantly promotes functional recovery even in chronic SCI,not only in additive but also in synergistic manner.Even though we have succeeded to outline the profiles of recovery secondary to the combination therapy,the mechanism underlying the effects remain unsolved.In this review article,we summarize the present progress and consider the prospect of the cell-based regenerative medicine particularly combined with rehabilitative approaches for chronic SCI animal models. | Syoichi Tashiro Masaya Nakamura Hideyuki Okano | 2017 | Neural Regeneration Research2017，12，1： | 4 |
| 2 | Neurorehabilitation using a voluntary driven exoskeletal robot improves trunk function in patients with chronic spinal cord injury: a single-arm study显示文摘Body weight-supported treadmill training with the voluntary driven exoskeleton(VDE-BWSTT) has been shown to improve the gait function of patients with chronic spinal cord injury. However, little is known whether VDE-BWSTT can effectively improve the trunk function of patients with chronic spinal cord injury. In this open-label, single-arm study, nine patients with chronic spinal cord injury at the cervical or thoracic level(six males and three females, aged 37.8 ± 15.6 years, and time since injury 51.1 ± 31.8 months) who underwent outpatient VDE-BWSTT training program at Keio University Hospital, Japan from September 2017 to March 2019 were included. All patients underwent twenty 60-minute gait training sessions using VDE. Trunk muscular strength, i.e., the maximum force against which patient could maintain a sitting posture without any support, was evaluated in four directions: anterior, posterior, and lateral(right and left) after 10 and 20 training sessions. After intervention, lateral muscular strength significantly improved. In addition, a significant positive correlation was detected between the change in lateral trunk muscular strength after 20 training sessions relative to baseline and gait speed. The change in trunk muscular strength after 20 training sessions relative to baseline was greatly correlated with patient age. This suggests that older adult patients with chronic spinal cord injury achieved a greater improvement in trunk muscle strength following VDE-BWSTT. All these findings suggest that VDE-BWSTT can improve the trunk function of patients with chronic spinal cord injury and the effect might be greater in older adult patients. The study was approved by the Keio University of Medicine Ethics Committee(IRB No. 20150355-3) on September 26, 2017. | Hiroki Okawara Syoichi Tashiro Tomonori Sawada Keiko Sugai Kohei Matsubayashi Michiyuki Kawakami Satoshi Nori Osahiko Tsuji Narihito Nagoshi Morio Matsumoto Masaya Nakamura | 2022 | Neural Regeneration Research2022，17，2： | 2 |
| 3 | Glucose effect on blood glucose in rats显示文摘 | Hamamoto Syoichi Kogami Hideharu Kohata Katsuya | 1999 | Yakuri to Chiryo1999，27，6： | 1 |
| 4 | Tough and Strong Ce-TZP/Alumina Nanocomposites Doped with Titania显示文摘 | Masahiro Nawa Syoichi Nakamoto Tohru Sekino | 1998 | Ceramics International1998，24，7： | 1 |
| 5 | Control of growth and development of protocorm like body derived from callus bycarbon sources in phalaenopsis显示文摘 | Obaidul Islam Syoichi Ichihashi Shuichiro Matsui | 1998 | Plant Biotechnology1998，15，4： | 1 |
| 6 | Evaluation of the effectiveness of color intensity analysis using a second‐generation autofluorescence imaging system for diminutive colorectal polyp differentiation显示文摘 | Naoto Tamai Syoichi Saito Hiroyuki Aihara Tomohiro Kato Hisao Tajiri | 2014 | Digestive Endoscopy2014，，： | 1 |
| 7 | Impact of Splenectomy in Patients with Gastric Adenocarcinoma of the Cardia显示文摘 | Chikara Kunisaki Hirochika Makino Hirokazu Suwa Tsutomu Sato Takashi Oshima Yasuhiko Nagano Syoichi Fujii Hirotoshi Akiyama Masato Nomura Yuichi Otsuka Hidetaka A. Ono Takashi Kosaka Ryo Takagawa Yasushi Ichikawa Hiroshi Shimada | 2007 | Journal of Gastrointestinal Surgery2007，，8： | 1 |
| 8 | Visualization of colorectal neoplasia by a second-generation autofluorescence imaging system显示文摘 | Daisuke Ide Naoto Tamai Hiroko Inomata Tomohiko R Ohya Hiroyuki Aihara Syoichi Saito Tomohiro Kato Hisao Tajiri | 2013 | Scandinavian Journal of Gastroenterology2013，，11： | 1 |
| 9 | Impact of Splenectomy in Patients with Gastric Adenocarcinoma of the Cardia显示文摘 | Chikara Kunisaki Hirochika Makino Hirokazu Suwa Tsutomu Sato Takashi Oshima Yasuhiko Nagano Syoichi Fujii Hirotoshi Akiyama Masato Nomura Yuichi Otsuka Hidetaka A. Ono Takashi Kosaka Ryo Takagawa Yasushi Ichikawa Hiroshi Shimada | 2007 | Journal of Gastrointestinal Surgery2007，，8： | 1 |
| 10 | Impact of Splenectomy in Patients with Gastric Adenocarcinoma of the Cardia显示文摘 | Chikara Kunisaki Hirochika Makino Hirokazu Suwa Tsutomu Sato Takashi Oshima Yasuhiko Nagano Syoichi Fujii Hirotoshi Akiyama Masato Nomura Yuichi Otsuka Hidetaka A. Ono Takashi Kosaka Ryo Takagawa Yasushi Ichikawa Hiroshi Shimada | 2007 | Journal of Gastrointestinal Surgery2007，，8： | 1 |
| 11 | 显示文摘 | Syoichi Y Takashi I | 1999 | IEEE Transactions on Magnetics1999，35，5： | 1 |
| 12 | Impact of Splenectomy in Patients with Gastric Adenocarcinoma of the Cardia显示文摘 | Chikara Kunisaki Hirochika Makino Hirokazu Suwa Tsutomu Sato Takashi Oshima Yasuhiko Nagano Syoichi Fujii Hirotoshi Akiyama Masato Nomura Yuichi Otsuka Hidetaka A. Ono Takashi Kosaka Ryo Takagawa Yasushi Ichikawa Hiroshi Shimada | 2007 | Journal of Gastrointestinal Surgery2007，，8： | 1 |
| 13 | 显示文摘 | Syoichi Y Takashi I Isao K | 1999 | IEEE Trans Magn1999，35，5： | 1 |
| 14 | Control of growth and development of protocorm like body derived from callus by carbon sources in Phalaenopsis 显示文摘 | Obaidul I Syoichi I Shuichiro M | 1998 | Plant Biotechnology1998，15，4： | 1 |
| 15 | Glucose effect on blood glucose in rats显示文摘 | Hamamoto Syoichi Kogami Hideharu Kohata Katsuya | 1999 | Yakuri to Chiryo1999，27，6： | 1 |
| 16 | Active engine mount with piezo actuator for vibration control显示文摘 | Takao Ushijima Syoichi Kumakawa | 1993 | SAE Paper1993，，2： | 1 |
| 17 | New hollandite catalysts for the selective reduction of nitrogen monoxide with propene显示文摘 | Syoichi Yamauchi Hiroshi Yamamura | 1995 | Applied Catalysis A:General1995，129，： | 1 |
| 18 | Glucose effect on blood glucose in rats 显示文摘 | Syoichi H Hideharu K Katsuya K | 1999 | Yakuri to Chiryo1999，27，6： | 1 |
| 19 | Learning Curve for Laparoscopy-assisted Distal Gastrectomy With Regional Lymph Node Dissection for Early Gastric Cancer显示文摘 | Chikara Kunisaki Hirochika Makino Naoto Yamamoto Tsutomu Sato Takashi Oshima Yasuhiko Nagano Syoichi Fujii Hirotoshi Akiyama Yuichi Otsuka Hidetaka A. Ono Takashi Kosaka Ryo Takagawa Hiroshi Shimada | 2008 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2008，，3： | 1 |
| 20 | Emotional Consequence of Telling a Lie显示文摘 | Megumi Sato Syoichi Iwasaki | 2013 | Journal of US-China Medical Science2013，10，5： | 0 |
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