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792篇 您的检索式:作者名="Sutherland R"
    题名 作者 年代 出处 被引量
1β-内酰胺酶抑制剂与抗生素耐药性的逆转显示文摘细菌对β—内酰胺类抗生素(青霉素类、头孢菌素类及其相关抗生素如头霉素类、青霉烯类、碳青霉烯类和单酰胺菌素类)产生耐药性的最重要机理是产生β—内酰胺酶。该酶能水解药物分子中的β—内酰胺键而使其失活。对于青霉素类,反应产物是青霉噻唑酸。头孢菌素类等则分解为较小分子产物。许多细菌产生β—内酰胺酶,一些细菌编码酶的基因位于染色体上,其余的则由染色体外成份介导,或由质粒介导,或由转座子介导。Sutherland R 刘小康 1993国外医药(抗生素分册)1993,14,4:6
2RNA binding proteins in spermatogenesis: an in depth focus on the Musashi family显示文摘控制基因规定为维持繁殖潜力在配偶子开发期间是重要的。在哺乳动物的精子发生的复杂过程期间,尽管有重翻译要求,男细菌房间为继续的生长和区别经历不活跃的抄写的扩大时期。因此,精子发生高度依赖基因表示的 posttranscriptional 规定的机制,由 RNA 有约束力的蛋白质(RBP ) 便于,它仍然保持富有地在整个这进程表示了。一如此的组蛋白质是 Musashi 家庭,以前在果蝇识别了睾丸细菌房间开发和成熟分裂的同样批评的管理者,并且也出现对在老鼠的精子开发和繁殖潜力重要。这评论在男细菌房间开发的范围以内描述 RBP 的角色和函数,集中于我们在精子发生的 Musashi 蛋白质的最近的知识。RBP 在房间以内利用的功能的机制在与模式的关系深入地亚 cellular 本地化和阶段特定的表示的,和意义被构画出, posttranscriptional 规定的影响也被加亮。当原来在果蝇和 Xenopus 描绘了,我们在干细胞功能和房间命运决心强调 RBP 的 Musashi 家庭的历史的角色,并且与我们微分角色的当前的理解和哺乳动物的 Musashi 蛋白质, Musashi-1 和 Musashi-2 的功能得出结论,与我们在精子发生的调查结果的一个主要焦点。这评论两个都作为男配偶子开发的主人管理者加亮 RBP 的必要贡献到 posttranscriptional 规定和 Musashi 家庭的重要性。Jessie M Sutherland Nicole A Siddall Gary R Hime Eileen A McLaughlin 2015Asian Journal of Andrology2015,17,4:4
3Exercise and adrenaline increase PGC-1 { alpha} mRNA expression in rat adipose tissue显示文摘SUTHERLAND L N BOMHOF M R CAPOZZI L C 2009J Physiol2009,587,7:1
4Dysregulation of Hedgehog,Wnt and Notch signallingpathways in breast cancer显示文摘Zardawi S J O’Toole S A Sutherland R L 2009Histol Histopathol2009,24,38:1
5Phenotypic char acterization of taste cells of the mouse small intestine显示文摘Sutherland K Young R L Cooper N J 2007Am J Physiol Gastrointest Liver Physiol2007,292,14:1
6Cell surface antigen CD109 is a novel member of the ct 2' maeroglobulin/C3, C4, C5 family of thioester-containing proteins 显示文摘Lin M Sutherland D R Horsfall W 2002Blood2002,99,5:1
7Caring for the older person in the emergency department:the ASET program and the role of the ASET clinical nurse consultant in South Western Sydney显示文摘Shanley C Sutherland S Tumeth R 0,,02:1
8Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial electrophysiology显示文摘Kumar S Sutherland F Rosso R 2011Heart Rhythm2011,8,4:1
9Identification of an opd(organophosphate degradtion) gene in an Agrobacterium isolate显示文摘Home I Sutherland Harcourt R 2002Applied and environmatal microbiology2002,68,7:1
10A Lead in grain size fractions of road deposited sediment显示文摘Sutherland R 2002Enviromental Pollution2002,121,:1
11Switchable reflective displays formed from holographic polymer-dispersed liquid crystals 显示文摘 Tondiglia V P Sutherland R L 2000SID ′00 Digest2000,31,:1
12A critical assessment of the research conducted at the hydraulics and erosion control laboratory-focus on rolled erosion control systems applied to hill slopes显示文摘 1998Geocells and Geomembranes1998,16,:1
13Runoff generation and sediment transport on unpaved roads, agricultural land surfaces in northern Thailand显示文摘Ziegler A D Sutherland R A Giambelluca T W 2000Earth Surface Processes and Landforms2000,25,5:1
14Partitioning inter- rill splash and wash dynamics: A novel laboratory approach 显示文摘WAN Y EL-SWAIFY S A SUTHERLAND R A 1996Soil Technology1996,9,:1
15One Hundred Questions of Importance to the Conservation of Global Biological Diversity 显示文摘SUTHERLAND W J ADAMS W M ARONSON R B 2009Conservation Biology2009,23,3:1
16Schlieren visualisation and measurement of axisymmetric disturbances显示文摘Sutherland B R Flynn M R Onu K 2003Nonlinear Processes in Geophysics2003,,10:1
17Finite-amplitude internal wavepacket disper- sion and breaking显示文摘Sutherland B R 2001Journal of Fluid Mechanics2001,429,:1
18Vitamin D levels,lung function,and steroid response in adult asthma显示文摘SUTHERLAND E R COLEVA E JACKSON L P 2010Am J Respir Crit Care Med2010,181,7:1
19Primers amplifying a range of Prunus S-alleles显示文摘Sutherland B G Robbins T P Tobutt K R 2004Plant Breeding2004,123,:1
20The use of high resolution melting (HRM) to map single nucleotide polymorphism markers linked to a covered smut resistance gene in barley 显示文摘Lehmensiek A Sutherland M W McNamara R B 2008Theor Appl Genet2008,117,5:1
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