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| 1 | Changing organ allocation policy for kidney transplantation in the United States显示文摘The new kidney allocation scheme(KAS) in effect since December 4th 2014 was designed to overcome the shortcomings of previous system. A key feature of the new KAS is preferential allocation of best quality organs to wait-list candidates with the longest predictivesurvival in a concept called longevity matching. Highly sensitized recipients would get extra points and enjoy widespread sharing of organs in order to increase accessibility to transplant. Wait-list candidates with blood group B will be offered organs from donors with A2 and A2 B blood type in order to shorten their wait-list time. Time on the wait list will start from day of listing or date of initiation of dialysis whichever comes first which should benefit candidates with limited resources who might be late to get on the transplant list. Pay back system has been eliminated in the new KAS. These changes in organ allocation policy may lead to increase in median half-life of the allograft and increase the number of transplants; thus resulting in better utilization of a scarce resource. There could be unintended negative consequences which may become evident over time. | Bhavna Chopra Kalathil K Sureshkumar | 2015 | World Journal of Transplantation2015，5，2： | 4 |
| 2 | Ad- sorption of uranium from aqueous solution using chi- tosan - tripolyphosphate (CTPP) beads显示文摘 | Sureshkumar M K Das D Mallia M B | 2010 | Journal of Hazardous Materials2010，184，1： | 1 |
| 3 | The influence of temperature on a mouse-mouse hybridoma growth and monoclonal antibody production显示文摘 | Sureshkumar G K Mutharasan R | 1991 | Biotechnol Bioeng1991，37，： | 1 |
| 4 | VanillinI 显示文摘 | Velavan R Sureshkumar P Sivakumar K | 1995 | Acta Crystallographica Section C : Crystal Structure Communications1995，51，6： | 1 |
| 5 | Role of steroid maintenance in sensitized kidney transplant recipients显示文摘AIM: To evaluate whether there is a threshold sensitization level beyond which benefits of chronic steroid maintenance(CSM) emerge. METHODS: Using Organ Procurement and Transplant Network/United Network of Organ Sharing database, we compared the adjusted graft and patient survivals for CSM vs early steroid withdrawal(ESW) among patients who underwent deceased-donor kidney(DDK) transplantation from 2000 to 2008 who were stratified by peak-panel reactive antibody(peak-PRA) titers(0%-30%, 31%-60% and > 60%). All patients received perioperative induction therapy and maintenance immunosuppression based on calcineurin inhibitor(CNI) and mycophenolate mofetil(MMF).RESULTS: The study included 42851 patients. In the 0%-30% peak-PRA class, adjusted over-all graft-failure(HR 1.11, 95%CI: 1.03-1.20, P = 0.009) and patientdeath(HR 1.29, 95%CI: 1.16-1.43, P < 0.001) risks were higher and death-censored graft-failure risk(HR 1.06, 95%CI: 0.98-1.14, P = 0.16) similar for CSM(n = 25218) vs ESW(n = 7399). Over-all(HR 1.04, 95%CI: 0.85-1.28, P = 0.70) and death-censored(HR 0.97, 95%CI: 0.78-1.21, P = 0.81) graft-failure risks were similar and patient-death risk(HR 1.39, 95%CI: 1.03-1.87, P = 0.03) higher for CSM(n = 3495) vs ESW(n = 850) groups for 31%-60% peak-PRA class. In the > 60% peak-PRA class, adjusted overall graft-failure(HR 0.90, 95%CI: 0.76-1.08, P = 0.25) and patientdeath(HR 0.92, 95%CI: 0.71-1.17, P = 0.47) risks were similar and death-censored graft-failure risk lower(HR 0.84, 95%CI: 0.71-0.99, P = 0.04) for CSM(n = 4966)vs ESW(n = 923).CONCLUSION: In DDK transplant recipients who underwent perioperative induction and CNI/MMF maintenance, CSM appears to be associated with increased risk for death with functioning graft in minimally-sensitized patients and improved death-censored graft survival in highly-sensitized patients. | Kalathil K Sureshkumar Richard J Marcus Bhavna Chopra | 2015 | World Journal of Transplantation2015，5，3： | 1 |
| 6 | Turbulent channel flow of dilute polymeric solutions :drag reduction scaling and an eddy viscosity model 显示文摘 | Li C F Gupta V K Sureshkumar R | 2005 | Journal of Non-Newtonian Fluid Mechanics2005，139，3： | 1 |
| 7 | Dynamic joint-aligned PIP and DIP corrective-flexion/extension orthosis for post burn finger contractures显示文摘 | Manigandan C Sureshkumar K Rachel R | 2005 | Burns2005，31，6： | 1 |
| 8 | Adsorptive removal of Cr (III) from aqueous solution using tripolyphosphate cross-linked chitosan beads 显示文摘 | DAS D SURESHKUMAR M K RADHAKRISHNAN K NUWAR J PILLAI C G S | 2011 | Journal of Radioanalytical and Nuclear Chemistry2011，289，1： | 1 |
| 9 | Antioxidant rich Morus alba leaf extract induces apoptosis in human colon and breast cancer cells by the down regulation of nitric oxide produced by inducible nitric oxide synthase显示文摘 | Deepa M Sureshkumar T Satheeshkumar P K | 2013 | Nutr Cancer2013，65，2： | 1 |
| 10 | Turbulentchannel flow of dilute polymeric solutions:drag reductionscaling and an eddy viscosity model显示文摘 | Li C F Gupta V K Sureshkumar R | 2006 | Non-NewtonianFluid Mech2006，139，3： | 1 |
| 11 | Magnetic antimicrobial nanocomposite based on bacterial cellulose and silver nanoparticles显示文摘 | Sureshkumar Mv Siswanto D Y Lee C K | 2010 | J Mater Chem2010，20，33： | 1 |
| 12 | Electron beam irradiation of LLDPE and PDMS rubber blends: Studies on the physicomechanical properties 显示文摘 | GIRl R SURESHKUMAR M S NASKAR K | 2008 | Adv PolymTech2008，27，2： | 1 |
| 13 | Kidney transplantation in older recipients:Preemptive high KDPI kidney vs lower KDPI kidney after varying dialysis vintage显示文摘AIM To evaluate the outcomes of transplanting marginal kidneys preemptively compared to better-quality kidneys after varying dialysis vintage in older recipients.METHODS Using OPTN/United Network for Organ Sharing database from 2001-2015, we identified deceased donor kidney(DDK) transplant recipients > 60 years of age who either underwent preemptive transplantation of kidneys with kidney donor profile index(KDPI) ≥ 85%(marginal kidneys) or received kidneys with KDPI of 35%-84%(better quality kidneys that older wait-listed patients would likely receive if waited longer) after being on dialysis for either 1-4 or 4-8 years. Using a multivariate Cox model adjusting for donor, recipient and transplant related factors-overall and death-censored graft failure risks along with patient death risk of preemptive transplant recipients were compared to transplant recipients in the 1-4 and 4-8 year dialysis vintage groups.RESUTLS The median follow up for the whole group was 37 mo(interquartile range of 57 mo). A total of 6110 DDK transplant recipients above the age of 60 years identified during the study period were found to be eligible to be included in the analysis. Among these patients350 received preemptive transplantation of kidneys with KDPI ≥ 85. The remaining patients underwent transplantation of better quality kidneys with KDPI 35-84% after being on maintenance dialysis for either 1-4 years(n = 3300) or 4-8 years(n = 2460). Adjusted overall graft failure risk and death-censored graft failure risk in preemptive high KDPI kidney recipients were similar when compared to group that received lower KDPI kidney after being on maintenance dialysis for either 1-4 years(HR 1.01, 95%CI: 0.90-1.14, P = 0.84 and HR 0.96, 95%CI: 0.79-1.16, P = 0.66 respectively) or 4-8 years(HR 0.82, 95%CI: 0.63-1.07, P = 0.15 and HR 0.81, 95%CI: 0.52-1.25, P = 0.33 respectively). Adjusted patient death risk in preemptive high KDPI kidney recipients were similar when compared to groups that received lower KDPI kidney after being on maintenance dialysis for 1-4 years(HR 0.99, 95%CI: 0.87-1.12, P = 0.89) but lower compared to patients who were on dialysis for 4-8 years(HR 0.74, 95%CI: 0.56-0.98, P = 0.037).CONCLUSION In summary, our study supports accepting a 'marginal' quality high KDPI kidney preemptively in older waitlisted patients thus avoiding dialysis exposure. | Bhavna Chopra Kalathil K Sureshkumar | 2018 | World Journal of Transplantation2018，8，4： | 1 |
| 14 | Effects of polymer stresses on eddy structures in dragleduced turbulent channel flow显示文摘 | Kim K Li C Sureshkumar R Balachandar S Adrian R J | 2007 | Journal of Fluid Mechanics2007，584，： | 1 |
| 15 | Biocatalytic reactions in hydro- phobic ionic liquids显示文摘 | Sureshkumar M Lee C K | 2009 | J Mol Catal B: Enzym2009，60，： | 1 |
| 16 | Passive scalar transport in polymer drag-reduced turbulent channel flow 显示文摘 | Gupta V K Sureshkumar R Khomami B | 2005 | AICHE Journal2005，51，7： | 1 |
| 17 | Purified mulberry leaf lectin (MLL) induces apoptosis and cell cycle ar- rest in human breast cancer and colon cancer cells显示文摘 | Deepa M Sureshkumar T Satheeshkumar P K | 2012 | Chem Bi- ol Interact2012，200，1： | 1 |
| 18 | Biocatalytic reactions in hydrophobic ionic liquids显示文摘 | Sureshkumar M Lee C K | 2009 | J Mol Catal B:Enzym2009，60，12： | 1 |
| 19 | Magnetic antimicrobial nanocomposite based on bacterial cellulose and silver nanoparticles显示文摘 | SURESHKUMAR M SISWANTO D Y LEE C K | | 0，，33： | 1 |
| 20 | Superiority of pediatric en bloc renal allografts over living donor kidneys:a long-term functional study显示文摘 | Sureshkumar K K Reddy C S Nighiem D D | 2006 | Transplantion2006，82，3： | 1 |
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