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| 1 | 睾丸后精子成熟,不育与高胆固醇血症显示文摘胆固醇是参与哺乳动物生理活动的重要分子,由于它是固醇类激素合成的通用前体物质,因而对生殖系统尤为重要。胆固醇不仅仅对于配子发生起到重要作用,它也是公认的精子功能的调节分子。胆固醇体内平衡的调节对睾丸后精子的成熟至关重要,胆固醇水平失衡会影响到睾丸后调控事件。代谢性脂质紊乱(血脂异常症)会影响男性的生育能力,但大多数这方面的研究是从内分泌/睾丸的角度进行探讨的,而这篇综述将关注像高胆固醇血症这样的特定血脂异常症在哺乳动物精子的睾丸后成熟过程中的有害影响。 | Marjorie Whitfield Xavier PoUet-Villard Rachel Levy Joel R Drevet Fabrice Saez | 2015 | Asian Journal of Andrology2015，17，5： | 8 |
| 2 | Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogenactivated protein kinase in mouse lung显示文摘 | Xin-qi PENG Mahendra DAMARLA Jarrett SKIRBALL Stephanie NONAS Xiao-ying WANG Eugenia J HAN Emile J HASAN Xuan CAO Adel BOUEIZ Rachel DAMICO Rubin M TUDER Alfred M SClUTO Dana R ANDERSON Joe GNGARCIA David A KASS Paul M HASSOUN Jun-tian ZHANG | 2010 | Acta Pharmacologica Sinica2010，31，2： | 6 |
| 3 | The epididymal immune balance:a key to preserving male fertility显示文摘Up to 15%of male in fertility has an immuno logical origi n,either due to repetitive infections or to autoimmune resp on ses mainly affecting the epididymis,prostate,and testis.Clinical observations and epidemiological data clearly contradict the idea that the testis confers immune protection to the whole male genital tract.As a consequenee,the epididymis,in which posttesticular spermatozoa mature and are stored,has raised some in terest in recent years when it comes to its immune mecha nisms.In deed,sperm cells are produced at puberty,long after the establishment of self-toleranee,and they possess unique surface proteins that cannot be recognized as self.These are potential targets of the immune system,with the risk of inducing autoantibodies and consequently male infertility.Epididymal immunity is based on a finely tuned equilibrium between efficient immune responses to pathogens and strong tolerance to sperm cells.These processes rely on incompletely described molecules and cell types.This review compiles recent studies focusing on the immune cell types populating the epididymis,and proposes hypothetical models of the organization of epididymal immunity with a special emphasis on the immune response,while also discussing important aspects of the epididymal immune regulation such as tolerance and tumour control. | Allison Voisin Fabrice Saez Joel R Drevet Rachel Guiton | 2019 | Asian Journal of Andrology2019，21，6： | 4 |
| 4 | Matrix-assisted laser desorption/ionization-mass spec- trometry of hydrophobic proteins in mixtures显示文摘 | RACHEL R O | 2011 | Sample Preparation in Biological Mass Spectrometry2011，10，3： | 1 |
| 5 | Using riskranking of metals to identify which poses the greatest threat to freshwater organisms in the UK显示文摘 | Rachel L R Andrew C J Claudia M | 2014 | Environmental Pollution2014，194，： | 1 |
| 6 | Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency显示文摘 | Rachel B Kapust R B Tozserl J | 2001 | Protein Eng2001，14，12： | 1 |
| 7 | Engineering the leagile supply chain显示文摘 | Rachel Mason-Jones Ben J Naylor and Denis R Towill | 2000 | International Journal of Agile Management Systems2000，2，1： | 1 |
| 8 | Enzyme production by obligate intestinal anaerobic bacteria isolated from oscars (Astronotus ocellatus),angelfish (Pterophyllum scalare) and southern flounder (Paralichthys lethostigma)显示文摘 | RACHEL F R BEVERLY A D | 2003 | Aquaculture2003，227，： | 1 |
| 9 | Are waist circumference and body mass index independently associated with cardiovascular disease risk in Chinese adults1,2,3显示文摘 | Rachel PW Gu DF Kristi R | 2005 | Am J Clin Nutr2005，81，： | 1 |
| 10 | Coastal water source of short- lived halocarbons in New England 显示文摘 | Zhou Y Ruth K V Rachel S R | 2005 | Journal of Geophysical Research2005，，： | 1 |
| 11 | A new phylum ofar- chaea represented by a nanosized hyperthermophilic sym- biont显示文摘 | Huber H Hohn M J Rachel R | 2002 | Nature2002，417，6884： | 1 |
| 12 | δPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo显示文摘 | Rachel B Gary K S Daria M R | 2007 | Brain Res2007，1144，1： | 1 |
| 13 | Telomere shortening in atherosclerosis显示文摘 | Nilesh J Samani Rachel Boultby Robert Butler John R Thompson Alison H Goodall | 2001 | The Lancet2001，，9280： | 1 |
| 14 | Activated carbon liron oxide magnetic composites for the adsorption of contaminants in water 显示文摘 | Oliveira Luiz C A Rios Rachel V R A Jos D | 2002 | Carbon2002，40，： | 1 |
| 15 | Clay-iron oxide magnetic composites for the adsorption of contaminants in water 显示文摘 | Luiz C A Oliveira Rachel V R A Rios Jose D Fabris | 2003 | Applied Clay Science2003，22，： | 1 |
| 16 | Clay-iron oxide magnetic composites for the adsorption of contaminants in water显示文摘 | Rachel V R A Jose' D | 2003 | Applied Clay Science2003，22，： | 1 |
| 17 | Appropriate bodymass index and waist circumference cutoffs for categorizationof overweight and central adiposity among Chinese adults显示文摘 | Rachel PW Dongfeng G Kristi R | 2004 | Am J Clin Nutr2004，80，5： | 1 |
| 18 | Personal involvement as a determinant of argument-based persuasion 显示文摘 | Petty R E John T C Rachel G | 1981 | Journal of Personality and Social Psychology1981，41，5： | 1 |
| 19 | Photoenolization as a means to release alcohols显示文摘 | Pika J Konosonoks A Rachel M R | 2003 | Journal of Organic Chemistry2003，68，5： | 1 |
| 20 | A comparison of tourists in Koh Phi Phi, Thailand and Gili Trawangan, Indonesia 显示文摘 | Rachel D Sonya R G Mark H | 2010 | Journal of Sustainable Tourism2010，22，3： | 1 |
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