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| 1 | Characterization and functions of beta defensins in the epididymis显示文摘附睾β - defensins 由重复基因复制和分叉演变编码对病原体提供直接保护并且也在它的主要功能支持男繁殖的道的蛋白质的一个家庭。男道 defensins 也从病原体攻击便于恢复。β - defensins 拥有古老的保存顺序和在多细胞的有机体普遍的结构的特征,在种幸存建议基本角色。首领 SPAG11,二祖先地独立的β - defensin 基因的功能的熔化,生产根据 tissue-specificand 被表示的或者拼接的抄本的一个大家庭种类特定的限制。SPAG11 的复杂性在哺乳动物的进化的不同分支变化。有主人蛋白质的人的 SPAG11D 的相互作用在多重发信号的小径显示参与。 | Susan H. Hall Suresh Yenugu Yashwanth Radhakrishnan Maria Christina W. Avellar Peter Petrusz Frank S. French | 2007 | Asian Journal of Andrology2007，9，4： | 18 |
| 2 | Corporate disclosures by family firms显示文摘 | Ashiq Ali Tai-Yuan Chen Suresh Radhakrishnan | 2007 | Journal of Accounting and Economics2007，，1： | 4 |
| 3 | Vendor certification and appraisal: Implications for supplier quality 显示文摘 | Hwang Iny Radhakrishnan Suresh Su Lixin | 2006 | Management Science2006，52，10： | 1 |
| 4 | Investor sophistication and patterns in stock returns after earnings announcements 显示文摘 | Bartov Eli Suresh Radhakrishnan hzhak Krinsky | 2000 | Accounting Review2000，75，1： | 1 |
| 5 | Vendor Certifica- tion and Appraisal:Implications for Supplier Quality显示文摘 | Iny Hwang Suresh Radhakrishnan Lixin(Nancy) Su | 2006 | Management Science2006，52，10： | 1 |
| 6 | Quaility implications of warranties in a supply chain 显示文摘 | Kashi R Balachandran Suresh Radhakrishnan | 2005 | Management Science2005，51，8： | 1 |
| 7 | Quality implications of warranties in a supply chain 显示文摘 | KASHI R Balachandran Suresh Radhakrishnan | 2005 | Management Science2005，51，： | 1 |
| 8 | The Declining Value Relevance of Accounting Information and Non Information-Based Trading : An Empirical Analysis 显示文摘 | Alex Dontoh Suresh Radhakrishnan Joshua Ronen | 2008 | Forthcoming : Contemporary Accounting Research2008，，21： | 1 |
| 9 | Vendor certification and appraisal: implications for supplier quality 显示文摘 | Iny Hwang Suresh Radhakrishnan | 2006 | Management Science2006，52，10： | 1 |
| 10 | Vendor Certification and Appraisal:Implications for Supplier Quality显示文摘 | Iny Hwang Suresh Radhakrishnan | 2006 | Management Science2006，52，10： | 1 |
| 11 | Job Challenge as a Motivator in a Principal-Agent Setting显示文摘 | Suresh Radhakrishnan | 1999 | European Journal of Operational Research1999，115，1： | 1 |
| 12 | Product Differentiation and Commonality in Design: Balancing Revenue and Cost Drivers显示文摘 | Preyas Desai Sunder Kekre Suresh Radhakrishnan Kannan Sriniva- san | 2001 | Management Science2001，47，1： | 1 |
| 13 | Vendor Certification and Appraisal: Implications for Supplier Quality 显示文摘 | Iny Hwang Suresh Radhakrishnan | 2006 | Management Science2006，52，10： | 1 |
| 14 | Characterization and phylogenetic analysis of antituberculous compound produ- cing actinomycete strain D25 isolated from That Desert soil, Rajasthan 显示文摘 | Radhakrishnan M Gopikrishnan V Suresh A | 2013 | Biomedical Informatics2013，9，： | 1 |
| 15 | Vendor certification and appraisal:Implications for supplier quality显示文摘 | Hwang Iny Radhakrishnan Suresh Su Lixin | 2006 | Management Science2006，52，10： | 1 |
| 16 | Quality Implications of Warranties in a Supply Chain显示文摘 | KASHI R BALACHANDRAN SURESH RADHAKRISHNAN | | 0，，08： | 1 |
| 17 | Anticancer efficacy of 3-(4-isopropyl)benzylidene-8-ethoxy,6-methyl,chroman-4-one(SBL-060),a novel,dual,estrogen receptor-Akt kinase inhibitor in acute myeloid leukemia cells显示文摘Estrogen receptor(ER)αis expressed in a subset of patient-derived acute myeloid leukemia(AML)cells,whereas Akt is predominantly expressed in most types of AML.Targeting AML with dual inhibitors is a novel approach to combat the disease.Herein,we examined a novel small molecule,3-(4-isopropyl)benzylidene-8-ethoxy,6-methyl,chroman-4-one(SBL-060),capable of targeting AML cells by inhibiting ERαand Akt kinase.The chemical properties of SBL-060 were identified by proton nuclear magnetic resonance(^(1)H-NMR),^(13)C-NMR,and mass spectroscopy.In silico docking was performed using an automated protocol with AutoDock-VINA.THP-1 and HL-60 cell lines were differentiated using phorbol 12-myristate 13-acetate.ERαinhibition was assessed using ELISA.The MTT assay assessed cell viability.Flow cytometry was performed for cell cycle,apoptosis,and p-Akt analyses.Chemical analysis identified the compound as 3-(4-isopropyl)benzylidene-8-ethoxy,6-methyl,chroman-4-one,which showed high binding efficacy toward ER,with aΔG_(binding) score of−7.4 kcal/mol.SBL-060 inhibited ERα,exhibiting IC50 values of 448 and 374.3 nM in THP-1 and HL-60 cells,respectively.Regarding inhibited cell proliferation,GI50 values of SBL-060 were 244.1 and 189.9 nM for THP-1 and HL-60 cells,respectively.In addition,a dose-dependent increase in sub G_(0)/G_(1) phase cell cycle arrest and total apoptosis was observed after treatment with SBL-060 in both cell types.SBL-060 also dose-dependently increased the p-Akt-positive populations in both THP-1 and HL-60 cells.Our results indicate that SBL-060 has excellent efficacy against differentiated AML cell types by inhibiting ER and Akt kinase,warranting further preclinical evaluations. | MESFER AL SHAHRANI PRASANNA RAJAGOPALAN MOHAMMAD ABOHASSAN MOHAMMAD ALSHAHRANI YASSER ALRAEY REEM MGAHTANI SURESH RADHAKRISHNAN KHLOOD DAGREERY | 2021 | Oncology Research2021，29，3： | 0 |
| 18 | The China puzzle: Opportunities for accounting research显示文摘How can China achieve phenomenal economic growth despite what is considered as 'weak' institutions in market-based economies? Xu(2011) provides a framework to understand this puzzle. Specifically, he suggests that China's institutional framework of Regionally Decentralized Authoritarian regime was likely responsible for the phenomenal economic growth despite what is considered 'weak' institutions for market-based economies. While recent accounting research provides insights into the relationship between agency issues, and accounting and control systems in the China context, accounting researchers can use the institutional feature of RDAs to provide insights into the role of accounting and control systems in non-market-based settings. | Suresh Radhakrishnan | 2014 | China Journal of Accounting Research2014，，1： | 0 |
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