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11篇 您的检索式：作者名="Suradej"

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		题名	作者	年代	出处	被引量
	1	Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion显示文摘AIM:To evaluate the expression of C-X-C motif chemokine receptor 4(CXCR4)and its signaling cascades,which were previously identified as a key factor for cancer cell progression and metastasis,in cholangiocarcinoma cell lines.METHODS:The expression of CXCR4 and its signaling cascades were determined in the cholangiocarcinoma cell lines(RMCCA1 and KKU100)by Western blotting.The invasion assays and the detection of actin polymerization were tested in these cholangiocarcinoma cells treated with CXC chemokine ligand-12(CXCL12).RESULTS:Expression of CXCR4 was detected in both cholangiocarcinoma cell lines and activation of CXCR4 with CXCL12 triggered the signaling via the extracellular signal-regulated kinase-1/2(ERK1/2)and phosphoinositide 3-kinase(PI3K)and induction of cholangiocarcinoma cell invasion,and displayed high levels of actin polymerization.Addition of CXCR4 inhibitor(AMD3100)abrogated CXCL12-induced phosphorylation of MEK1/2 and Akt in these cells.Moreover,treatment with MEK1/2 inhibitor(U0126)or PI3K inhibitor(LY294 002)also attenuated the effect of CXCL12-induced cholangiocarcinoma cell invasion.CONCLUSION:These results indicated that the activation of CXCR4 and its signaling pathways(MEK1/2 and Akt)are essential for CXCL12-induced cholangiocarcinoma cell invasion.This rises Implications on a potential role for the inhibition of CXCR4 or its signal cascades in the treatment of cholangiocarcinoma.	Kawin Leelawat Surang Leelawat Siriluck Narong Suradej Hongeng	2007	World Journal of Gastroenterology2007，13，10：	27
	2	Effective osteosarcoma cytolysis using cytokine-induced killer cells pre-inoculated with tumor RNA-pulsed dendritic cells显示文摘	Adisak Wongkajornsilp Sakdipat Sangsuriyong Suradej Hongeng Saranatra Waikakul Apichat Asavamongkolkul Sukit Huabprasert	2005	Journal of Orthopaedic Research2005，，6：	3
	3	Generation of CD3+CD56+ Cytokine-Induced killer cells and their in vitro cytotoxicity against pédiatrie cancer cells显示文摘	Suradej Hongeng Sawang Pctviscs Surapon Worapongpaiboon Busaba Rcrkamnuaychoke Samart Pakakasama Saengsuree Jootar	2003	International Journal of Hematology2003，，2：	1
	4	A study on yields and nutrient element compositions of sugarcane显示文摘	SURADEJ J KASEM S	1999	Kasetsait Journal:Social Sciences1999，33，1：	1
	5	Preparation of self-solidifying polymeric depots from PLEC-PEG-PLEC triblock copolymers as an in- jectable drug delivery system 显示文摘	Wannarong K Suradej H Jitladda S	2012	Jlnt Pharm2012，19，3：	1
	6	Generation of CD3 + CD56 + Cytokine-Induced Killer Cells and Their In Vitro Cytotoxicity against Pediatric Cancer Cells显示文摘	Suradej Hongeng Sawang Pctviscs Surapon Worapongpaiboon Busaba Rcrkamnuaychoke Samart Pakakasama Saengsuree Jootar	2003	International Journal of Hematology2003，，2：	1
	7	Preparation of self-so- lidifying polymeric depots from PLEC-PEG-PLEC triblock copoly- mers as an injectable drug delivery system显示文摘	Wannarong K Suradej H Jitladda S	2012	J Polym Res2012，19，3：	1
	8	Generation of CD3+CD56+ Cytokine-Induced killer cells and their in vitro cytotoxicity against pédiatrie cancer cells显示文摘	Suradej Hongeng Sawang Pctviscs Surapon Worapongpaiboon Busaba Rcrkamnuaychoke Samart Pakakasama Saengsuree Jootar	2003	International Journal of Hematology2003，，2：	1
	9	Preparation of self-so- lidifying polymeric depots from PLEC-PEG-PLEC triblock eopoly mers as all injeetable drug delivery system显示文摘	Wannarong K Suradej H Jitladda S	2012	Jlnt Pharm2012，19，3：	1
	10	Prepara- tion of self-solidifying polymeric depots from PLEC-PEG-PLEC triblock copolymers as an injectable drug delivery system 显示文摘	WANNARONG K SURADEJ H JITLADDA S	2012	J lnt Pharm2012，19，3：	1
	11	Generation of CD3+CD56+ Cytokine-Induced killer cells and their in vitro cytotoxicity against pédiatrie cancer cells显示文摘	Suradej Hongeng Sawang Pctviscs Surapon Worapongpaiboon Busaba Rcrkamnuaychoke Samart Pakakasama Saengsuree Jootar	2003	International Journal of Hematology2003，，2：	1

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