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102篇 您的检索式:作者名="Hongeng"
    题名 作者 年代 出处 被引量
1Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion显示文摘AIM:To evaluate the expression of C-X-C motif chemokine receptor 4(CXCR4)and its signaling cascades,which were previously identified as a key factor for cancer cell progression and metastasis,in cholangiocarcinoma cell lines.METHODS:The expression of CXCR4 and its signaling cascades were determined in the cholangiocarcinoma cell lines(RMCCA1 and KKU100)by Western blotting.The invasion assays and the detection of actin polymerization were tested in these cholangiocarcinoma cells treated with CXC chemokine ligand-12(CXCL12).RESULTS:Expression of CXCR4 was detected in both cholangiocarcinoma cell lines and activation of CXCR4 with CXCL12 triggered the signaling via the extracellular signal-regulated kinase-1/2(ERK1/2)and phosphoinositide 3-kinase(PI3K)and induction of cholangiocarcinoma cell invasion,and displayed high levels of actin polymerization.Addition of CXCR4 inhibitor(AMD3100)abrogated CXCL12-induced phosphorylation of MEK1/2 and Akt in these cells.Moreover,treatment with MEK1/2 inhibitor(U0126)or PI3K inhibitor(LY294 002)also attenuated the effect of CXCL12-induced cholangiocarcinoma cell invasion.CONCLUSION:These results indicated that the activation of CXCR4 and its signaling pathways(MEK1/2 and Akt)are essential for CXCL12-induced cholangiocarcinoma cell invasion.This rises Implications on a potential role for the inhibition of CXCR4 or its signal cascades in the treatment of cholangiocarcinoma.Kawin Leelawat Surang Leelawat Siriluck Narong Suradej Hongeng 2007World Journal of Gastroenterology2007,13,10:27
2Effective osteosarcoma cytolysis using cytokine-induced killer cells pre-inoculated with tumor RNA-pulsed dendritic cells显示文摘Adisak Wongkajornsilp Sakdipat Sangsuriyong Suradej Hongeng Saranatra Waikakul Apichat Asavamongkolkul Sukit Huabprasert 2005Journal of Orthopaedic Research2005,,6:3
3Outcomes of transplantation with related - and unrelated - donor stem cells in children with severe thalassemia显示文摘HONGENG S PAKAKASAMA S CHUANSUMRIT A 2006Biol Blood Marrow Transplant2006,12,6:1
4Effective osteosarcoma cytolysis using cytokine-induced killer cells pre-inoculated with tumor RNA-pulsed dendritic cells显示文摘Wongkajornsilp A Sangsuriyong S Hongeng S 2005J Orthop Res2005,23,6:1
5Generation of CD3^+ CD56^+ cytokine-induced killer cells and their in vitro cytotoxicity againstpediatric cancer cells 显示文摘Hongeng S Petvises S Worapongpaiboon S 2003Int J Hematol2003,77,2:1
6Generation of CD3^+ CD56^+ cytokine-induced killer cells and their in vitro cytotoxicity against pediatric cancer cells显示文摘Hongeng S Petvises S Worapongpaiboon S 2003Int J Hematol2003,77,2:1
7Video-Based Event Recogni- tion: Activity Representation and Prohabilistic Recognition Methods 显示文摘Hongeng S Nivatia R Bremond F 2004Computer Vision and Image Understanding2004,96,2:1
8Successful treatment of refrac-tory autoimmune haemolytic anaemia in a post-unrelated bone marrow transplant paediatric patient with rituximab显示文摘HONGENG S TARDTONG P WORAPONG-PAIBOON S 2002Bone Marrow Transplant2002,29,:1
9Effectiveosteosarcoma cytolysis using cytokine-induced killer cellspre-inoculated with tumor RNA-pulsed dendritic cells显示文摘Wongkajornsilp A Sangsuriyong S Hongeng S 2005JOrthop Res2005,23,6:1
10Generation of CD3^+ CD56^+ cytokine - induced killer and their in vitro cytotoxicity against pediatric cancer cells 显示文摘Hongeng S Petvises S Worapongpaiboon S 2003Int J Hematol2003,77,2:1
11Generation of CD3 + CD56 + cytokine-induced killer cells and their in vitro cytotoxicity against pediatric cancer cells 显示文摘HONGENG S PETVISES S WORAPONGPAIBOON S 2003Int J Hematol2003,77,2:1
12Generation of CD3^+CD56^+ cytokine induced killer cells and their in vitro cytotoxicity against pediatric cancer cells显示文摘Hongeng S Petvises S Worapongpaiboon S 2003Iht J Hematol2003,77,2:1
13Allogeneic peripheral blood stem cell transplantation in children with homozygous β-thalassemia and severe β-thalassemia/hemoglobin E disease显示文摘Pakakasama S Hongeng S Chaisiripoomkere W 2004J Pediatr Hematol Oricol2004,26,4:1
14Effective osteosarcoma cytolysis using eytokine-indueed killer ceils pre-inoculated with tumor RNA-pulsed dendritic cells 显示文摘WONGKAJORNSILP A SANGSURIYONG S HONGENG S 2005J Orthop Res2005,23,6:1
15Generation of CD3+CD56+ cytokine-induced killer cell and in vitro cytotoxicity against pediatric cancer cells显示文摘Hongeng S Petvises S Worapongpaiboon S 0,,02:1
16Generation of CD3+ CD56+ cytokine-induced killer cells and their in vitro cytotoxicity against pediatric cancer cells 显示文摘Hongeng S Petvises S Worapongpaiboon S 2003Int J Hematol2003,77,2:1
17Successful treatment of refractory autoimmune haemolytic anaemia in a postunrelated bone marrow transplant paediatric patient with rituximab显示文摘Hongeng S Tardtong P Worapongpaiboon S 0,,:1
18Generation of CD3^+ CD56^ cytokine-induced killer cells and their in vitro cytotoxicity against pediatric cancer cells显示文摘Hongeng S Petvises S Worapongpaiboon S 2003Int J Hematol2003,77,2:1
19Video-based event recognition: Activity representation and probabilistie recognition Methods显示文摘Hongeng S Nevatia R Bremond F 2004Computer Vision and Image Understanding2004,96,2:1
20Generation of CD3^+ CD56^+ cytokine-induced killer ceils and their in vitro cytotoxicity against pediatric cancer cells 显示文摘Hongeng S Petvises S Worapongpaiboon S 2003Int J Hematol2003,77,2:1
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