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| 1 | 在常规创伤治疗中,通过选择敷料减轻疼痛的重要性:MAPP研究显示文摘目的阐明由于各种原因引起的急慢性伤口患者,除去敷料时疼痛的发生率和改用新型抗粘连敷料的效果。方法共有656名主治医生,报告了在研究期间、常规随访时所观察到的全部急性或慢性伤口的有关详细情况,对换药时感到的疼痛进行了系统的评估。对于中到重度患者,进行更全面的评估,并且请他们完成一个自我评估调查问卷。如果患者参加了随后的随访,将重新评估。结果在全部5850名患者中,2914名患者有急性伤口,2936名患者有慢性伤口。在筛查访问期间,报告换药时存在中度到重度疼痛的急性和慢性伤口的患者数量差不多(79.9%和79.7%),在家完成的自我评估调查问卷中报告存在重度疼痛的急性和慢性伤口的患者数量也差不多(分别为47%和59%)。当敷料和伤口床存在粘连时,取下敷料时非常疼痛。在88%的慢性伤口和95%的急性伤口患者中,改用新型的抗粘连敷料能够降低换药时的疼痛。结论本研究表明,不论创伤的病因如何,患者对治疗的可接受性均出现了类似的问题。疼痛是一个大问题,常常与敷料选择有关,选择合适的抗粘连敷料能够提高患者的可接受性。 | S.Meaume Ivry Sur Seine I.Lazareth J.Martini S.Bohbot | 2005 | 中国实用护理杂志2005，21，9： | 10 |
| 2 | Antidepressant-Like Effects of Hesperidin in Animal Model of Post-Traumatic Stress Disorder显示文摘Objective:Post-traumatic stress disorder(PTSD)is a psychiatric disorder characterized by depression and anxiety,that arises due to an imbalance of neurotransmitters in response to excessive stress.Hesperidin(HSD)is a naturally occurring flavonoid shown to exert a variety of biological activities,including antioxidant,anti-inflammatory,and neuroprotective effects.Methods:This study was used the open field test(OFT)and forced swimming test(FST)to examine the effects of HSD on the depression-like response of rats after exposure to a single prolonged stress(SPS)leading to the dysregulation of the serotonergic activation system.Male rats were given HSD(20,50,and 100 mg/kg,intraperitoneal injection,n=6–7 per group)once daily for 14 days after exposure to SPS.The influence of administration of HSD on SPS-induced behavioral responses and concentrations of serotonin(5-HT),5-hydroxyindoleacetic acid(5-HIAA),and monoamine oxidase-A(MAO-A)in the rat brain were also investigated using enzyme-linked immunoassays(ELISAs).Results:Daily HSD administration significantly improved depression-like behaviors in the FST(P<0.05),increased the number of lines crossed in the central zone of the OFT(P<0.01),and reduced freezing behavior both in contextual and cued fear conditioning.HSD treatment also attenuated the reduction in SPS-induced 5-HT concentrations in the hippocampus and amygdala.This increase in 5-HT concentrations during HSD treatment was partially attributed to a decrease in the 5-HIAA/5-HT ratio in the hippocampus of rats with PTSD.Furthermore,HSD treatment inhibited activity of MAO-A and decreases of tryptophan hydroxylase-1 expression in the hippocampus.Conclusion:HSD was shown to exert antidepressant effects in rats exposed to SPS,suggesting that this natural flavonoid may be an effective medicine for PTSD. | Bombi Lee Gwang Muk Choi Bongjun Sur | 2021 | Chinese Journal of Integrative Medicine2021，27，1： | 4 |
| 3 | MeCP2: Making sense of missense in Rett syndrome显示文摘 | Abhishek Banerjee Esmeralda Romero-Loren Mriganka Sur | 2013 | Cell Research2013，23，11： | 3 |
| 4 | Structural and Optical Properties of Nanocrystal In203 Films by Thermal Oxidation of In2S3 Films显示文摘 | M. OEztas M. Bedir Z. OEztürk D. Korkmaz S. Sur | 2006 | Chinese Physics Letters2006，23，6： | 3 |
| 5 | 人胎盘提取液的抗炎和抗血小板聚集作用显示文摘AIM:To find the anti-inflammatory and anti-platelet aggregatory acivity of human placental extract(HPE,Placentrex),METHODS:The HPE was studied for anti-inflammatory effect in wistar rats on carrageenin,serotonin(5-HT),and prostaglandin E1(PGE1) induced edema in acute model and cotton pellet induced granuloma on sub-acute model.Anti-platelet aggregation was studied against protection of adinosine diphosphate (ADP)-induced aggregation of human platelet through in vitro study,RESULTS:HPE showed positive results both in acute and sub-acute models of inflammation.Highly significant(P<0.01),results were obtained against 5-HT induced acute inflammation and cotton pellet induced sub-acute inflammation in comparison with standard (diclofenac sodium)and control (normal saline) drugs.The anti-inflammatory property of HPE in animal model was well supported with clincal study of platelet aggregation.There was highly significant (P<0.01) inhibition of platelet aggregation with HPE at different doses against ADP.CONCLUSION:Our data suggest that human placental extract may be useful in suppressing inflammation and platelet aggregation. | SUR Tapas Kumar BISWAS Tuhin Kanti ALI Liaquat MUKHERJEE Biswapati | 2003 | Acta Pharmacologica Sinica2003，24，2： | 2 |
| 6 | Detection of canine parvovirus in naturally infected dogs with enteritis and myocarditis by in situ hybridization 显示文摘 | Nho W G Sur J H Doster A R | 1997 | J Vet Diagn Invest1997，9，3： | 1 |
| 7 | Treatment of ureteral calculus obstruction with laser lithotripsy in an Atlantic bottlenose dolphin ( Tursiops trun- eatus) 显示文摘 | Schmitt TL Sur RL | 2012 | J Zoo Wildl Med2012，43，1： | 1 |
| 8 | Modulation of neutrophil NETosis: interplay between infectious agents and underlying host physiology显示文摘 | Sinuhe Hahn Stavros Giaglis Chanchal Sur Chowdury Irene H?sli Paul Hasler | 2013 | Seminars in Immunopathology2013，，4： | 1 |
| 9 | Development of a flux-less soldering method by ultrasonic modulated laser显示文摘 | Ming Yu Li Chun Qing Wang Han Sur Bang Young Pyo Kim | 2005 | Journal of Materials Processing Tech2005，，2： | 1 |
| 10 | Eosinophil survival activity identified as interleukin-5 is associated with eosinophil recruit- ment and degranulation and lung injury twenty-four hours after segmental antigen lung challenge显示文摘 | Ohnishi T Sur S Collins DS | 1993 | J Allergy Clin Immunol1993，92，： | 1 |
| 11 | Effect of oil on heat transfer and pressure drop during condensation of refrigerant-113 inside smooth and internally finned tues 显示文摘 | Sur B Azer N Z | 1991 | ASHRAE Trans1991，97，： | 1 |
| 12 | Palliative thoracic radio-therapy in lung cancer: An American Society for Radiation Oncolo- gy evidence-based clinical practice guideline 显示文摘 | Rodrigues G Videtic GMM Sur R | 2011 | Pract Radiat On- col2011，1，2： | 1 |
| 13 | Vesicular stomatitis virus infection and neuropathogenesis in the routine model are associated with apoptosis 显示文摘 | Sur J H Ailende R Doster A R | 2003 | Veterinary Pathology2003，40，5： | 1 |
| 14 | The role of the papilloma virus in esophageal cancer显示文摘 | Sur M Cooper K | 1998 | Pathology1998，30，4： | 1 |
| 15 | Orientation maps of subjective contours invisual cortex显示文摘 | Sheth B.R Sharma J Rao S.C Sur M | | 0，，： | 1 |
| 16 | Trigonella foenum - graecum(fenugreek) seed extract as an antineoplastic agent 显示文摘 | Sur P Das M Comes A | 2001 | Phy - tother Res2001，15，3： | 1 |
| 17 | Invivo detection of Prrs vanaby in situ hybridization at different times post infection 显示文摘 | Sur J H Copper V L Gale ota J A | 1996 | Jclin Microbial1996，34，9： | 1 |
| 18 | Prevalence and distribution of oral lesions:a cross-sectional study in Turkey 显示文摘 | Mumeu G Cimilli H Sur H | 2005 | Oral Dis2005，11，2： | 1 |
| 19 | Diverse Role of Silicon Carbide in the Domain of Nanomaterials显示文摘 | T. Sahu B. Ghosh S. K. Pradhan T. Ganguly Ujjal Kumar Sur | 2012 | International Journal of Electrochemistry2012，，： | 1 |
| 20 | Embryo volumemeasurement: an intraobserver, intermethod comparative studyof semiautomated and manual three-dimensional ultrasoundtechniques显示文摘 | Sur SD Clewes JS Campbell BK | 2011 | Ultrasound Obstet Gynecol2011，38，5： | 1 |
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