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| 1 | The Dual Effects of Interleukin-18 in Tumor Progression显示文摘Interleukin-18 (IL-18) was discovered as an interferon-γ-inducing factor and had a critical role in inflammatory and immune response. It stimulates natural killer (NK) and T cells and enhances Th1 immune response. These activated immune cells eliminate cancer cells and virus-infected cells effectively. However,IL-18 has also been found to promote tumor progression. Higher expression or secretion level of IL-18 is detected in various cancer cells in comparison with normal control,and IL-18 is able to induce angiogenesis,migration/metastasis,proliferation and immune escape. These dual effects and the mechanism of IL-18 need to be investigated further as it relates to cancer. | Sunyoung Park Soyoung Cheon Daeho Cho | 2007 | Cellular & Molecular Immunology2007，4，5： | 20 |
| 2 | Chondrogenesis of periodontal ligament stem cells by transforming growth factor-β3 and bone morphogenetic protein-6 in a normal healthy impacted third molar显示文摘The periodontal ligament-derived mesenchymal stem cell is regarded as a source of adult stem cells due to its multipotency. However, the proof of chondrogenic potential of the cells is scarce. Therefore, we investigated the chondrogenic differentiation capacity of periodontal ligament derived mesenchymal stem cells induced by transforming growth factor (TGF)-β3 and bone morphogenetic protein (BMP)-6. After isolation of periodontal ligament stem cells (PDLSCs) from human periodontal ligament, the cells were cultured in Dulbecco's modified Eagle's medium (DMEM) with 20% fetal bovine serum (FBS). A mechanical force initiated chondrogenic differentiation of the cells. For chondrogenic differentiation, 10 μg ·L-1 TGF-β3 or 100 μg ·L-1 BMP-6 and the combination treating group for synergistic effect of the growth factors. We analyzed the PDLSCs by fluorescence-activated cell sorting and chondrogenesis were evaluated by glycosaminoglycans assay, histology, immunohistochemistry and genetic analysis. PDLSCs showed mesenchymal stem cell properties proved by FACS analysis. Glycosaminoglycans contents were increased 217% by TGF-β3 and 220% by BMP-6. The synergetic effect of TGF-β3 and BMP-6 were shown up to 281% compared to control. The combination treatment increased Sox9, aggrecan and collagen II expression compared with not only controls, but also TGF-β3 or BMP-6 single treatment dramatically. The histological analysis also indicated the chondrogenic differentiation of PDLSCs in our conditions. The results of the present study demonstrate the potential of the dental stem cell as a valuable cell source for chondrogenesis, which may be applicable for regeneration of cartilage and bone fracture in the field of cell therapy. | Sunyoung Choi Tae-Jun Cho Soon-Keun Kwon Gene Lee Jaejin Cho | 2013 | International Journal of Oral Science2013，5，1： | 5 |
| 3 | Cardinality compensation method based on information-weighted consensus filter using data clustering for multi-target tracking显示文摘In this paper, a cardinality compensation method based on Information-weighted Consensus Filter(ICF) using data clustering is proposed in order to accurately estimate the cardinality of the Cardinalized Probability Hypothesis Density(CPHD) filter. Although the joint propagation of the intensity and the cardinality distribution in the CPHD filter process allows for more reliable estimation of the cardinality(target number) than the PHD filter, tracking loss may occur when noise and clutter are high in the measurements in a practical situation. For that reason, the cardinality compensation process is included in the CPHD filter, which is based on information fusion step using estimated cardinality obtained from the CPHD filter and measured cardinality obtained through data clustering. Here, the ICF is used for information fusion. To verify the performance of the proposed method, simulations were carried out and it was confirmed that the tracking performance of the multi-target was improved because the cardinality was estimated more accurately as compared to the existing techniques. | Sunyoung KIM Changho KANG Changook PARK | 2019 | Chinese Journal of Aeronautics2019，32，9： | 3 |
| 4 | MicroRNA maturation: stepwise processing and subcellular localization显示文摘 | Yoontae Lee Kipyoung Jeon Jun‐Tae Lee Sunyoung Kim V. Narry Kim | 2002 | The EMBO Journal2002，，： | 2 |
| 5 | Correlation between electrode-tissue impledance and motion artifact in biopotential recordings显示文摘 | Buxi Dilpreet Kim Sunyoung Helleputte Nick Van | 2012 | IEEE Sensors Journal2012，12，12： | 1 |
| 6 | Topological studies of spinach 22 Kda protein of photosystem Ⅱ显示文摘 | SUNYOUNG K ERAN P CHARCLES F Y | 1994 | Biochimica et Biophysica Acta1994，1188，1994： | 1 |
| 7 | Radiotherapy-induced secondary cancer risk for breast cancer:3D conformal therapy versus IMRT versus VMAT显示文摘 | Boram Lee Sunyoung Lee Jiwon Sung | 2014 | Journal of radiological protection:Official journal of the Society for Radiological Protection2014，34，2： | 1 |
| 8 | Overexpres- sion of IL-32ctincreases natural killer cell-mediated killing through up-regulation of Fas and UL16-binding protein 2 (ULBP2) Ex- pression in Human Chronic Myeloid Leukemia Cells 显示文摘 | Soyoung Cheon Ji Hyung Lee Sunyoung Park | 2011 | The Journal of Biological Chemistry2011，286，12： | 1 |
| 9 | Enhanced Degradation of 2,4,6-Trinitrotoluene(TNT)in a Soil Column: Planted with Indian Mallow (Abutilon avicennae) 显示文摘 | Yoonyoung C Youngseok K Sunyoung K | 2004 | Journal of Bioscienee and Bioengineering2004，97，2： | 1 |
| 10 | Quantitative detection of porcine torque teno virus in porcine circovirus-2-negative and porcine circovirus-associated disease-affected pigs显示文摘 | Lee S S Sunyoung S Jung H | 2010 | J Vet Diagn Invest2010，22，2： | 1 |
| 11 | Acidity of Group 5 Metal (V,Nb,Ta)-Substituted Keggin and Wells-Da- wson Heteropolyacid (HPA) Catalysts and Their Application to Esterification of Acetic Acid with Ethanol 显示文摘 | Dong Ryul Park Sunyoung Park Jung Ho Choi | 2010 | Catalysis Lette~2010，135，34： | 1 |
| 12 | A1E inhibits proliferation and induces apoptosis in NCI-H460 lung cancer cells via extrinsic and intrinsic pathways显示文摘 | Yesol Bak Sunyoung Ham O. Baatartsogt Seung hyun Jung Kang-Duk Choi Tae-Young Han Il-Young Han Do-Young Yoon | 2013 | Molecular Biology Reports2013，，7： | 1 |
| 13 | Preparation of polymerbound palladium catalyst and its application to the reduction of nitro arenes and the hydrodehalogenation of aryl halides显示文摘 | Hongkeun M Sunyoung L Minhan P | 2014 | Journal of Organometallic Chemistry2014，755，： | 1 |
| 14 | Correlation Between electrode-tissue Impledance and motion artifact in biopoten- tial recordings显示文摘 | Dilpreet Buxi Sunyoung Kim Nick van Helleputte | 2012 | IEEE sensors journal2012，12，12： | 1 |
| 15 | Failure analysis of a planetary gear carrier of 1200HP transmission显示文摘 | Sunyoung Park Jongmin Lee Uijun Moon Deugjo Kim | 2009 | Engineering Failure Analysis2009，，2： | 1 |
| 16 | Germination inhibitory constituents from Erigeron annuus显示文摘 | Hyuncheol Oh Sunyoung Lee Ho-Sub Lee | 2002 | Phytochemistry2002，61，： | 1 |
| 17 | Efficacy of chlorine dioxide gas against Alicyclobacillus restris spores on apple surfaces显示文摘 | Lee Sunyoung Dance GI Chang Susen | 2006 | International Journal of Food Microbiology2006，108，3： | 1 |
| 18 | Prevalence of type-specific oncogenic human papillomavirus infection assessed by HPV E6/E7 mRNA among women with high-grade cervical lesions显示文摘 | Hye-young Wang Sunyoung Park Dongsup Lee Sunghyun Kim Geehyuk Kim Kwang Hwa Park Hyeyoung Lee | 2015 | International Journal of Infectious Diseases2015，，： | 1 |
| 19 | Career satisfaction, organizational commitment, and turnover intention: The effects of goal orientation, organizational learning culture and developmental feedback显示文摘 | Baek-Kyoo (Brian) Joo Sunyoung Park | 2010 | Leadership & Organization Development Journal2010，，6： | 1 |
| 20 | Pain relief by cyberknife radiosurgery for spinal metastasis显示文摘 | Sunyoung Lee Mison Chun | 2012 | Tumori2012，98，2： | 1 |
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