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| 1 | The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a chronic,progressive and debilitating disease,which affects over 2.5 million people in China.PD is characterized clinically by resting tremor,muscular rigidity,bradykinesia and postural instability.As the disease progresses,additional complications can arise such as non-motor and neurobehavioral symptoms.Pharmacological treatment and surgical intervention for PD have been implemented in China.Until 10 years ago,there was lack of standardization for the management of PD in different regions and among different physicians,leading to different treatment levels in different regions and different physicians.Since then,the Chinese Parkinson’s Disease and Movement Disorder Society have published three versions of guidelines for the management of PD in China,in 2006,2009 and 2014,respectively.Correspondingly,the overall level of treatment for PD in China improved.Objectives:To update the treatment guidelines based on current foreign and domestic practice guidelines and clinical evidence,and to improve the treatment options available to physicians in the management of PD.Summary:A variety of treatment recommendations in the treatment guidelines have been proposed,including physical activity and disease-modifying medication,which should be initiated at the early-stage of the disease.The principles of dosage titration should be followed to avoid acute adverse reactions to the drugs,to achieve a satisfactory clinical effect with a low dose and to reduce the incidence of long-term motor complications.Moreover,different treatment strategies should be considered at different stages of the disease.Importantly,treatment guidelines and personalized treatments should be valued equally.A set of treatment recommendations has been developed to assist physicians to improve and optimize clinical outcomes for patients with PD in China. | Shengdi Chen Piu Chan Shenggang Sun Haibo Chen Baorong Zhang Weidong Le Chunfeng Liu Guoguang Peng Beisha Tang Lijuan Wang Yan Cheng Ming Shao Zhenguo Liu Zhenfu Wang Xiaochun Chen Mingwei Wang Xinhua Wan Huifang Shang Yiming Liu Pingyi Xu Jian Wang Tao Feng Xianwen Chen Xingyue Hu Anmu Xie Qin Xiao | 2016 | Translational Neurodegeneration2016，5，1： | 23 |
| 2 | Active disturbance rejection control on first-order plant显示文摘Conventional PI control encounters some problems when dealing with large lag process in the presence of parameter uncertainties.For the typical first-order process,an observerbased linear active disturbance rejection control(LADRC) scheme is presented to cope with the difficulties,and a reduced-order observer scheme is proposed further.Some quantitative dynamic results with regard to non-overshoot characteristics are obtained.Finally,the performance boundaries of LADRC and PI control are explicitly compared with each other,which shows that the former is more superior in most cases. | Ruiguang Yang Mingwei Sun Zengqiang Chen | 2011 | Journal of Systems Engineering and Electronics2011，22，1： | 20 |
| 3 | Combining LPJ-GUESS and HASM to simulate the spatial distribution of forest vegetation carbon stock in China显示文摘它在因为他们在陆上的生态系统的碳股票拥有大率,精确地在地区性的规模估计森林碳股票和空间分发是很重要的。然而,在地区性的规模的森林碳存货的当前的评价主要取决于森林库存数据,并且整个过程消费太多劳动,钱和时间。并且同时,它在森林碳存储上有许多否定影响更新。以便弄明白这些问题,基于当模特儿的高精确性表面(HASM ) ,这份报纸建议一个森林植被碳存储模拟方法。这个新方法作为 HASM 的起始的值采用 LPJ 猜测模型的输出并且把库存数据用作 HASM 的样品点在中国模仿森林碳存储的分发。这研究也作为数据来源采用中国的第七森林资源统计产生样品点,并且它也作为模拟精确性测试工作。HASM 模拟证明中国的全部的森林碳存储是 9.2405 Pg,当计算价值基于森林资源统计是 7.8115 Pg 时。森林资源统计基于森林华盖闭合被拿,并且 HASM 的结果对真实森林碳存储更合适。模拟结果也显示西南的山区域和东北森林是在中国的重要森林碳水库,并且他们分别地说明 39.82% 国家和 20.46% 总数森林植被碳存货。与以前的价值(1975-1995 ) 相比,二个区域的碳存储确实清楚地增加,这表明。这研究的结果证明在在中国的最后十年的大规模重新造林达到一个重要的碳水池。 | ZHAO Mingwei YUE Tianxiang ZHAO Na SUN Xiaofang ZHANG Xingying | 2014 | Journal of Geographical Sciences2014，24，2： | 18 |
| 4 | A fundamental theorem for eco-environmental surface modelling and its applications显示文摘We propose a fundamental theorem for eco-environmental surface modelling(FTEEM) in order to apply it into the fields of ecology and environmental science more easily after the fundamental theorem for Earth’s surface system modeling(FTESM). The Beijing-Tianjin-Hebei(BTH) region is taken as a case area to conduct empirical studies of algorithms for spatial upscaling, spatial downscaling, spatial interpolation, data fusion and model-data assimilation, which are based on high accuracy surface modelling(HASM), corresponding with corollaries of FTEEM. The case studies demonstrate how eco-environmental surface modelling is substantially improved when both extrinsic and intrinsic information are used along with an appropriate method of HASM. Compared with classic algorithms, the HASM-based algorithm for spatial upscaling reduced the root-meansquare error of the BTH elevation surface by 9 m. The HASM-based algorithm for spatial downscaling reduced the relative error of future scenarios of annual mean temperature by 16%. The HASM-based algorithm for spatial interpolation reduced the relative error of change trend of annual mean precipitation by 0.2%. The HASM-based algorithm for data fusion reduced the relative error of change trend of annual mean temperature by 70%. The HASM-based algorithm for model-data assimilation reduced the relative error of carbon stocks by 40%. We propose five theoretical challenges and three application problems of HASM that need to be addressed to improve FTEEM. | Tianxiang YUE Na ZHAO Yu LIU Yifu WANG Bin ZHANG Zhengping DU Zemeng FAN Wenjiao SHI Chuanfa CHEN Mingwei ZHAO Dunjiang SONG Shihai WANG Yinjun SONG Changqing YAN Qiquan LI Xiaofang SUN Lili ZHANG Yongzhong TIAN Wei WANG Ying’an WANG Shengnan MA Hongsheng HUANG Yimin LU Qing WANG Chenliang WANG Yuzhu WANG Ming LU Wei ZHOU Yi LIU Xiaozhe YIN Zong WANG Zhengyi BAO Miaomiao ZHAO Yapeng ZHAO Yimeng JIAO Ufra NASEER Bin FAN Saibo LI Yang YANG John PWILSON | 2020 | Science China Earth Sciences2020，63，8： | 7 |
| 5 | Protonation induced high-T_c phases in iron-based superconductors evidenced by NMR and magnetization measurements显示文摘Chemical substitution during growth is a well-established method to manipulate electronic states of quantum materials, and leads to rich spectra of phase diagrams in cuprate and iron-based superconductors. Here we report a novel and generic strategy to achieve nonvolatile electron doping in series of(i.e.11 and 122 structures) Fe-based superconductors by ionic liquid gating induced protonation at room temperature. Accumulation of protons in bulk compounds induces superconductivity in the parent compounds, and enhances the Tclargely in some superconducting ones. Furthermore, the existence of proton in the lattice enables the first proton nuclear magnetic resonance(NMR) study to probe directly superconductivity. Using Fe S as a model system, our NMR study reveals an emergent high-Tcphase with no coherence peak which is hard to measure by NMR with other isotopes. This novel electric-fieldinduced proton evolution opens up an avenue for manipulation of competing electronic states(e.g.Mott insulators), and may provide an innovative way for a broad perspective of NMR measurements with greatly enhanced detecting resolution. | Yi Cui Gehui Zhang Haobo Li Hai Lin Xiyu Zhu Hai-Hu Wen Guoqing Wang Jinzhao Sun Mingwei Ma Yuan Li Dongliang Gong Tao Xie Yanhong Gu Shiliang Lie Huiqian Luo Pu Yu Weiqiang Yu | 2018 | Science Bulletin2018，63，1： | 7 |
| 6 | Cation-mixing stabilized layered oxide cathodes for sodium-ion batteries显示文摘Sodium-ion batteries are promising for large-scale energy storage due to sodium's low cost and infinite abundance. The most popular cathodes for sodium-ion batteries, i.e., the layered sodium-containing oxides, usually exhibit reversible host rearrangement between P-type and O-type stacking upon charge/discharge. Herein we demonstrate that such host rearrangement is unfavorable and can be suppressed by introducing transition-metal ions into sodium layers. The electrode with stabilized P3-type stacking delivers superior rate capability, high energy efficiency, and excellent cycling performance. Owing to the cation-mixing nature, it performs the lowest lattice strain among all reported cathodes for sodium-ion batteries. Our findings highlight the significance of a stable host for sodium-ion storage and moreover underline the fundamental distinction in material design strategy between lithium-and sodium-ion batteries. | Shaohua Guo Yang Sun Pan Liu Jin Yi Ping He Xiaoyu Zhang Yanbei Zhu Ryosuke Senga Kazu Suenaga Mingwei Chen Haoshen Zhou | 2018 | Science Bulletin2018，63，6： | 5 |
| 7 | High AOA decoupling control for aircraft based on ADRC显示文摘In this paper, a practical decoupling control scheme for fighter aircraft is proposed to achieve high angle of attack(AOA)tracking and super maneuver action by utilizing the thrust vector technology. Firstly, a six degree-of-freedom(DOF) nonlinear model with 12 variables is given. Due to low sufficiency of the aerodynamic actuators at high AOA, a thrust vector model with rotatable engine nozzles is derived. Secondly, the active disturbance rejection control(ADRC) is used to realize a three-channel decoupling control such that a strong coupling between different channels can be treated as total disturbance, which is estimated by the designed extended state observer. The control surface allocation is implemented by the traditional daisy chain method. Finally,the effectiveness of the presented control strategy is demonstrated by some numerical simulation results. | LIU Junjie SUN Mingwei CHEN Zengqiang SUN Qinglin | 2020 | Journal of Systems Engineering and Electronics2020，31，2： | 5 |
| 8 | An Improved Filter of Progressive TIN Densification for LiD AR Point Cloud Data显示文摘Based on the classic filter of progressive triangulated irregular network(TIN) densification, an improved filter is proposed in this paper. In this method, we divide ground points into grids with certain size and select the lowest points in the grids to reconstruct TIN in the process of iteration. Compared with the classic filter of progressive TIN densification(PTD), the improved method can filter out attached objects, avoid the interference of low objects and obtain relatively smooth bare-earth. In addition, this proposed filter can reduce memory requirements and be more efficient in processing huge data volume. The experimental results show that the filtering accuracy and efficiency of this method is higher than that of the PTD method. | WANG Huan WANG Shugen CHEN Qi JIN Weihua SUN Mingwei | 2015 | Wuhan University Journal of Natural Sciences2015，20，4： | 3 |
| 9 | THE PRINCIPLE OF ROBUSTNESS IN GENERALIZED PREDICTIVE CONTROL显示文摘This paper deeply analyzes the closed-loop nature ofGPCin the fram ework ofinter- nalm odelcontrol(IMC) theory. A new sort ofrelation lies in the feedback structure so that robustreason can be satisfactorily explained. The resultissignificantbecause the previous con- clusions are only applied to open-loop stable plant(orm odel). | Sun Mingwei Chen Zengqiang Yuan Zhuzhi Dept. of Com puterand System Science, NankaiUniv., Tianjin 300071. | 1999 | Applied Mathematics(A Journal of Chinese Universities)1999，14，3： | 3 |
| 10 | Can Fluorine-18 Fluoroestradiol Positron Emission Tomography–Computed Tomography Demonstrate the Heterogeneity of Breast Cancer In Vivo?显示文摘 | Zhongyi Yang Yifei Sun Yongping Zhang Jing Xue Mingwei Wang Wei Shi Beiling Zhu Silong Hu Zhifeng Yao Herong Pan Yingjian Zhang | 2013 | Clinical Breast Cancer2013，，： | 2 |
| 11 | A high-accuracy method for simulating the XCO_2 global distribution using GOSAT retrieval data显示文摘A high-accuracy surface modeling(HASM)method based on the fundamental theorem of surfaces,is developed to simulate XCO_2 surfaces using the GOSAT retrieval XCO_2 data.Two tests are designed to investigate the simulation accuracy.The first test divides the existing satellite retrieval XCO2 data into training points and testing points,and simulates the XCO2 surface using the training points while computing the simulation error using the testing points.The absolute mean error(MAE)of the testing points is 1.189 ppmv,and the corresponding values of the comparison methods,Ordinary Kriging,IDW,and Spline are1.203,1.301,and 1.355 ppmv,respectively.The second test simulates the XCO_2 surface using all the satellite retrieval points and uses the TCCON(Total Carbon Column Observing Network)site observation values as the ture values.For the six typical TCCON sites,the HASM simulation MAE is 1.688 ppmv,and the satellite retrieval MAE at the same sites is 2.147 ppmv.These results indicate that HASM can successfully simulate XCO_2 surfaces based on satellite retrieval data. | ZHAO MingWei ZHANG XingYing YUE TianXiang WANG Chun JIANG Ling SUN JingLu | 2017 | Science China Earth Sciences2017，60，1： | 2 |
| 12 | Reinforcement learning based parameter optimization of active disturbance rejection control for autonomous underwater vehicle显示文摘This paper proposes a liner active disturbance rejection control(LADRC) method based on the Q-Learning algorithm of reinforcement learning(RL) to control the six-degree-of-freedom motion of an autonomous underwater vehicle(AUV).The number of controllers is increased to realize AUV motion decoupling.At the same time, in order to avoid the oversize of the algorithm, combined with the controlled content, a simplified Q-learning algorithm is constructed to realize the parameter adaptation of the LADRC controller.Finally, through the simulation experiment of the controller with fixed parameters and the controller based on the Q-learning algorithm, the rationality of the simplified algorithm, the effectiveness of parameter adaptation, and the unique advantages of the LADRC controller are verified. | SONG Wanping CHEN Zengqiang SUN Mingwei SUN Qinglin | 2022 | Journal of Systems Engineering and Electronics2022，33，1： | 1 |
| 13 | General trends in the structural, electronic and elastic properties of the M 3 AlC 2 phases (M=transition metal): A first-principle study显示文摘 | Xiaodong He Yuelei Bai Chuncheng Zhu Yue Sun Mingwei Li M.W. Barsoum | 2010 | Computational Materials Science2010，，3： | 1 |
| 14 | A novel disturbance-observer based friction compensation scheme for ball and plate system显示文摘 | Yongkun Wang Mingwei Sun Zenghui Wang Zhongxin Liu Zengqiang Chen | 2013 | ISA Transactions2013，，： | 1 |
| 15 | Bridging the structure gap between pellets in artificial dissolution media and in gastro-intestinal tract in rats显示文摘Changes in structure of oral solid dosage forms(OSDF) elementally determine the drug release and its therapeutic effects.In this research,synchrotron radiation X-ray micro-computed tomography was utilized to visualize the 3 D structure of enteric coated pellets recovered from the gastrointestinal tract of rats.The structures of pellets in solid state and in vitro compendium media were measured.Pellets in vivo underwent morphological and structural changes which differed significantly from those in vitro compendium media.Thus,optimizations of the dissolution media were performed to mimic the appropriate in vivo conditions by introducing pepsin and glass microspheres in media.The sphericity,pellet volume,pore volume and porosity of the in vivo esomeprazole magnesium pellets in stomach for2 h were recorded 0.47,1.55 × 10^(8)μm^(3),0.44 × 10^(8)μm^(3)and 27.6%,respectively.After adding pepsin and glass microspheres,the above parameters in vitro reached to 0.44,1.64 × 10^(8)μm^(3)0.38 × 10^(8)μm^(3)and 23.0%,respectively.Omeprazole magnesium pellets behaved similarly.The structural features of pellets between in vitro media and in vivo condition were bridged successfully in terms of 3 D structures to ensure better design,characterization and quality control of advanced OSDF. | Hongyu Sun Siyu He Li Wu Zeying Cao Xian Sun Mingwei Xu Shan Lu Mingdi Xu Baoming Ning Huimin Sun Tiqiao Xiao Peter York Xu Xu Xianzhen Yin Jiwen Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 1 |
| 16 | ADRC control onfirst -order plant显示文摘 | Yang Ruiguang Sun Mingwei | 2011 | Journal of system engineering and e- lectronics2011，25，1： | 1 |
| 17 | Prognostic factors in children with acute fulminant myocarditis receiving venoarterial extracorporeal membrane oxygenation显示文摘Background Pediatric acute fulminant myocarditis(AFM)is a very dangerous disease that may lead to acute heart failure or even sudden death.Previous reports have identified some prognostic factors in adult AFM;however,there is no such research on children with AFM on venoarterial extracorporeal membrane oxygenation(VA-ECMO).This study aimed to find relevant prognostic factors for predicting adverse clinical outcomes.Methods A retrospective analysis was performed in an affiliated university children’s hospital with consecutive patients receiving VA-ECMO for AFM from July 2010 to November 2020.These children were classified into a survivor group(n=33)and a non-survivor group(n=8).Patient demographics,clinical events,laboratory findings,and electrocardiographic and echocardiographic parameters were analyzed.Results Peak serum creatinine(SCr)and peak creatine kinase isoenzyme MB during ECMO had joint predictive value for in-hospital mortality(p=0.011,AUC=0.962).Based on multivariable logistic regression analysis,peak SCr level during ECMO support was an independent predictor of in-hospital mortality(OR=1.035,95%CI 1.006 to 1.064,p=0.017,AUC=0.936,with optimal cut-off value of 78μmol/L).Conclusion Tissue hypoperfusion and consequent end-organ damage ultimately hampered the outcomes.The need for left atrial decompression indicated a sicker patient on ECMO and introduced additional risk for complications.Earlier and more cautious deployment would likely be associated with decreased risk of complications and mortality. | Mingwei Sun Qing Zong Li Fen Ye Yong Fan Lijun Yang Ru Lin | 2022 | World Journal of Pediatric Surgery2022，5，1： | 1 |
| 18 | Proportion integral-type active disturbance rejection generalized predictive control for distillation process based on grey wolf optimization parameter tuning显示文摘The high-purity distillation column system is strongly nonlinear and coupled,which makes it difficult to control.Active disturbance rejection control(ADRC)has been widely used in distillation systems,but it has limitations in controlling distillation systems with large time delays since ADRC employs ESO and feedback control law to estimate the total disturbance of the system without considering the large time delays.This paper designs a proportion integral-type active disturbance rejection generalized predictive control(PI-ADRGPC)algorithm to control the distillation column system with large time delay.It replaces the PD controller in ADRC with a proportion integral-type generalized predictive control(PI-GPC),thereby improving the performance of control systems with large time delays.Since the proposed controller has many parameters and is difficult to tune,this paper proposes to use the grey wolf optimization(GWO)to tune these parameters,whose structure can also be used by other intelligent optimization algorithms.The performance of GWO tuned PI-ADRGPC is compared with the control performance of GWO tuned ADRC method,multi-verse optimizer(MVO)tuned PI-ADRGPC and MVO tuned ADRC.The simulation results show that the proposed strategy can track reference well and has a good disturbance rejection performance. | Jia Ren Zengqiang Chen Mingwei Sun Qinglin Sun Zenghui Wang | 2022 | Chinese Journal of Chemical Engineering2022，35，9： | 1 |
| 19 | Protective effects of gastrodia elata on aluminium-chloride-induced learning impairments and alterations of amino acid neurotransmitter release in adult rats显示文摘 | He Shuchang Niu Qiao Niu Piye He Mingwei Sun Xiaoshu Shao Feng Wang Sheng Mark Opler | 2008 | Restorative Neurology and Neuroscience2008，，6： | 1 |
| 20 | Metal recycling from waste memory modules efficiently and environmentally friendly by low-temperature alkali melts显示文摘Recycling of waste electrical and electronic equipment has become an urgent global issue in recent years from the prospectives of resources recycling and environmental protection.In the present work,the recycling of waste memory modules(WMMs)through low-temperature alkali melts was investigated,based on the thermodynamic analysis of the nonmetallic reactions of brominated epoxy resin,glass fiber and memory chip with the molten mixed alkali.The effects of the reaction temperature and the ratio of alkali mixture on the removal rate of nonmetallic parts in WMMs were discussed under the condition of air atmosphere.The optimum process parameters were further confirmed by in-situ monitoring of the temperature during the whole reaction process.The mixtures with Cu,Fe and Ni as the main components were obtained after the treatment of WMMs in the molten alkali.These mixed metals were further separated into copper-rich and ferronickel-rich metals by physical magnetic separation.Moreover,the precious metals Au and Ag were enriched in Cu-rich alloys.This work provided an efficient and environment-friendly method for metal recycling from WMMs. | ZHU MingWei MA HaoBo HE Jie CHEN Bin ZHANG LiLi JIANG HongXiang SUN XiaoJun ZHAO JiuZhou | 2020 | Science China(Technological Sciences)2020，63，11： | 1 |
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