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| 1 | Necessity and indications of invasive treatment for Budd-Chiari syndrome显示文摘BACKGROUND:The development of collaterals in Budd-Chiari syndrome has been described and these collaterals play an important role in the presentation of this disease.These collaterals are diagnostic and their use in management strategy has never been evaluated.This study aimed to investigate the indications,feasibility and necessity of invasive treatment for patients with Budd-Chiari syndrome and to determine whether such a strategy is necessary for optimal management.METHODS:Twenty-nine patients who had been treated at our unit were enrolled in this study.Based on physical and biochemical examination,and hemodynamic compensation by collaterals,18 patients underwent radiological intervention (group A),while the other 11 had no invasive treatment (group B).The related hemodynamic parameters were acquired when percutaneous angiography was performed.RESULTS:In group A,all patients underwent successfully inferior vena cava (IVC) balloon angioplasty with or without stenting.Four patients also underwent hepatic vein angioplasty.In these patients,the mean IVC pressure before and after treatment was statistically different (29.3±9.2 vs 15.1±4.6 mmHg,P<0.01).The mean IVC pressure was much lower in group B than in group A (12.9±2.4 vs 29.3±9.2 mmHg,P<0.01),but there was no difference from that of the patients after radiological treatment (12.9±2.4 vs 15.1±4.6 mmHg,P>0.05).Median follow-up was 32.3 months (mean 21.3 months;range 3-61 months).In the course of follow-up,the patients in group A survived with good systemic status except for re-stenosis in one patient who underwent re-canalization of the IVC.In group B,10 patients had good systemic status except one patient who had a meso-caval shunt because of deterioration.CONCLUSIONS:The rationale of 'early diagnosis and early treatment' is not suitable for all patients with Budd-Chiari syndrome.Satisfactory survival can be achieved in some patients without invasive treatment,who are completely compensated by rich collaterals.Nonetheless,a positive treatment procedure should be performed if the patient's situation worsens in the course of regular follow-up. | Department of General Surgery (Fu Y,Sun YL,Ma XX,Xu PQ,Feng LS,Tang Z and Luo CH),Institute of Hepatic Vascular Disease (Sun YL),Department of Radiological Intervention (Guan S and Wang ZW),First Affiliated Hospital,Zhengzhou University School of Medicine,Zhengzhou 450052,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 10 |
| 2 | A retrospective cohortstudy of the association of anesthesia and hernia repair surgery withbehavioral and developmental disorders in young children显示文摘 | DiMaggio C Sun LS Kakavouli A | 2009 | JNeurosurg Anesthesiol2009，21，： | 1 |
| 3 | Effects of expression level of DNA repair-related genes involved in the NHEJ path- way on radiation-induced cognitive impairment 显示文摘 | ZHANG LY CHEN LS SUN R | 2013 | Radiat Res2013，54，2： | 1 |
| 4 | The antioxidant alpha- lipoic acid improves endothelial dysfunction induced by acute hyperglycaemia during OGTF in impaired glucose tolerance显示文摘 | Xiang GD Sun HL Zhao LS | 2008 | Clin Endocrinol (Oxf)2008，68，5： | 1 |
| 5 | Corticosteroid pharmacokinetics in the inner ear fluids:an animal study followed by clinical application显示文摘 | Parnes LS Sun AH Freeman DJ | 1999 | Laryngoscope1999，109，： | 1 |
| 6 | Corticosteroid pharmacokinetics in the inner ear fluids : an animal study followed by clinical application 显示文摘 | Parnes LS Sun AI-I Freeman DJ | 1999 | Laryngoscope1999，109，72： | 1 |
| 7 | Li G,DiMaggio Cv et al, Anesthesia and neurodcvelopment in children: time for an Answer显示文摘 | Sun LS | 2008 | Anesthesi- 0Iogy2008，109，5： | 1 |
| 8 | C orticosteroid phannacokinetics in theinner ear fluids :an animal study followed by clinical application显示文摘 | Parnes LS Sun AH Freeman DJ | 1999 | Larynogoscope1999，109，7： | 1 |
| 9 | Feasibility and pilot sudy of the Pediatric Anesthesia Neurodevelopment Assessment (PANDA) Project显示文摘 | Sun LS Li G DiMaggio CJ | 2012 | J Neurosurg Anesthesiol2012，24，4： | 1 |
| 10 | Prevalence, clinical manifestations and endoseopie features of eosinophilic esophagitis: a pathological review in China显示文摘 | Shi YN Sun SJ Xiong LS | 2012 | J Dig Dis2012，13，6： | 1 |
| 11 | Report of the Third PANDA Symposium on 'Anesthesia and Neurodevelopment in Children' 显示文摘 | Miller TL Park R Sun LS | 2012 | J Neurosurg Anesthesiol2012，24，4： | 1 |
| 12 | Corticsteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application显示文摘 | Parnnes LS Sun AH Freeman DJ | 1999 | Laryngoscope1999，，： | 1 |
| 13 | Cellular mechanisms underlying acquired epilepsy:the calcium hypothesis of the induction and maintainance of epilepsy显示文摘 | DeLorenzo RJ Sun DA Deshpande LS | | 0，，： | 1 |
| 14 | Feasibility and pilot study of the Pediatric Anesthesia NeureDevelopment Assessment (PAN- DA) project 显示文摘 | Sun LS Li G DiMaggio CJ | 2012 | J Neurosurg Anesthesiol2012，24，4： | 1 |
| 15 | Report of the Fourth PANDA Symposium on' Anesthesia and Neurodevelopment in Children' 显示文摘 | Miller TLv Park R Sun LS | 2014 | J Neurosurg Anesthesiol2014，26，4： | 1 |
| 16 | Sex-based differences in serum cardiac troponin Ⅰ, a specific marker formyocardial injury, after cardiac surgery显示文摘 | Schwarzenberger JC Sun LS Pesce MA | 2003 | Crit Care Med2003，31，3： | 1 |
| 17 | Prevalence of malignant hyperthermia due to anesthesia in New York State, 2001 -2005 显示文摘 | Brady JE Sun LS Rosenberg H | 2009 | AnesthAnalg2009，109，4： | 1 |
| 18 | Fiberoptic intubation withdexmedetomidine in two children with spinal cord impingements 显示文摘 | Jouste EH Ohkawa S Sun LS | 2005 | Anesthesia & Analgesia2005，101，： | 1 |
| 19 | Creatine feeding increase Glut - 4 expression in rat skeletal musele显示文摘 | Jeong- Sun J Jill LS Peter JO | 2005 | Amphysiol Endocri nol2005，，288： | 1 |
| 20 | A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in central south Chinese population显示文摘 | Wu LS Li FF Sun LD | 2011 | Hum Genet2011，130，6： | 1 |
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