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| 1 | Hepatoprotective effect of Woodfordia fruticosa Kurz flowers on diclofenac sodium induced liver toxicity in rats显示文摘Objective:To evaluate the protective effect of Woodfordia fruticosa Kurz flowers against experimentally induced liver toxicity in rats.Methods:Two different doses of methanol extract of Woodfordia fruticosa(WFM) were evaluated for the hepatoprotective activity against diclofenac sodium induced hepatotoxicity in rats.Various biochemical parameters like alanine aminotransferase(ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP),total protein(TP),albumin(ALB),blood urea nitrogen(BUN) from serum;total protein(TP),glutathione (GSH) levels,catalase(CAT) and glutathione peroxidase(GPx) activities from liver were studied; histopathologic changes of liver were also evaluated.Results:WFM effectively reduced the elevated levels of serum ALT,AST,ALP and BUN,enhanced the reduced TP,ALB and hepatic GSH,CAT,GPx activity.The histopathological analysis suggested that WFM decreased the degree of liver fibrosis induced by diclofenac.Conclusions:This study demonstrates the hepatoprotective activity of WFM and thus scientifically support the use of this plant in traditional medicine for the treatment of liver disorders. | Yogesh Baravalia Yogeshkumar Vaghasiya Sumitra Chanda | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，5： | 2 |
| 2 | Protective effect of Polyalthia longifolia var.pendula leaves on ethanol and ethanol/HCl induced ulcer in rats and its antimicrobial potency显示文摘Objective:To explore antiulcer and antimicrobial properties of methanolic extract of Polyalthia longifolia var.pendula.Methods:Gastroprotective potential of Polyalthia longifolia was studied on ethanol and ethanol/HCl induced ulcers at 2 different doses(270 and 540 mg/kg/body weight). Antimicrobial efficacy of Polyalthia longifolia(25 mg/mL) was also studied against six gram positive,seven gram negative bacteria and five fungi by agar well diffusion method.Minimum inhibitory concentration was determined by agar well diffusion method in two fold serial dilution, in the range of 97-25 000μg/mL.Results:The reduction of ulcer index in Polyalthia longifolia treated animals was found to be statistically significant with respect to control animals.The Polyalthia longifolia exhibited ulcer protection activity in dose dependent manner and was also better than the standard.In antimicrobial activity,gram positive bacteria were more susceptible to Polyalthia longifolia than gram negative bacteria and fungal strains.Conclusions:Results obtained confirm the antiulcer and antimicrobial potential of the Polyalthia longifolia. | Sumitra Chanda Yogesh Baravalia Mital Kaneria | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，9： | 2 |
| 3 | Effect of mercury toxicity on hypocotyl elongation and cell wall loosening in Phaseolus seedlings显示文摘 | Mor Ilza R Gokani Sonal J Chanda Sumitra V | 2002 | Journal of Plant Nutrition2002，25，4： | 1 |
| 4 | Assessment of effect of hydroalcoholic and decoction methods on extraction of antioxidants from selected Indian medicinal plants显示文摘Objective:To assess the effects of extraction methods on antioxidant activities of selected Indian medicinal flora.Methods:Different parts of plants were extracted by hydroalcoholic and decoction methods using water and various concentrations of methanol(ME) viz.75%, 50%and 25%ME.The antioxidant activity of all the different extracts was evaluated using two different antioxidant assays viz.2,2-diphenyl-1-picryl hydrazyl(DPPH) free radical scavenging assay and superoxide anion radical scavenging assay.Total phenol and flavonoid content was also estimated.Results:The results showed that the extracting solvent significantly altered the antioxidant property estimations of screened plants.High correlations between phenolic compositions and antioxidant activities of extracts were observed.High levels of antioxidant activities were detected in Manilkara zapota(M.zapota) as compared with other screened plants. Conclusions:The results obtained appear to confirm the effect of different methods on extraction of antioxidants and antioxidant property of M.zapota. | Mital Kaneria Bhavana Kanani Sumitra Chanda | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，3： | 1 |
| 5 | Effica- cy of aqueous and methanol extracts of some medicinal plants for potential antibacterial activity 显示文摘 | Jigna Parekh Darshana Jadeja Sumitra Chanda | 2005 | Turk J Bi- ol2005，29，： | 1 |
| 6 | In vitro antibacterial activity and phytochemical analysis of some Indian medic- inal plants 显示文摘 | Jigna Parekh Sumitra V Chanda | 2007 | Turk J Biol2007，31，： | 1 |
| 7 | Efficacy of Aqueous and Methanol Extracts of Some Medicinal Plants for Potential Antibacterial Activity显示文摘 | Jigna PAREKH Darshana JADEJA Sumitra CHANDA | 2005 | Turk J Biol2005，29，： | 1 |
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