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| 1 | Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined. | Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu | 2022 | Stroke & Vascular Neurology2022，7，1： | 7 |
| 2 | Identification of tro- pomyosins as major allergens in an tarctic krill and mantis shrimp and the amino acid sequence characteristics 显示文摘 | Motoyam A K Sum A Y Ishizaki S | 2008 | Mar Biotechnol (NY)2008，10，6： | 1 |
| 3 | Theelectrochemical performances of Ti-V-based hydrogen storage composite electrodes prepared by ball milling method 显示文摘 | QIU S J CHU H L ZHANG Y SUM L X XU F CAO Z | 2008 | International Journal of Hydrogen Energy2008，33，24： | 1 |
| 4 | The Recovery of Metals from Electronic Scrap 显示文摘 | | 1991 | JOM1991，，： | 1 |
| 5 | Substituting fish meal with soybean meal in diets of juvenile cobia Rachycentron canadum显示文摘 | CHOU R L HER B Y SUM S | 2004 | Auqaculture2004，229，： | 1 |
| 6 | Clinical significance of vascular endothelial growth factor expression in gastric cancer显示文摘 | Kakeji Y Koga T Sum iyoshi Y | 2002 | J Exp Clin Cancer Res2002，21，1： | 1 |
| 7 | Dexmedetomidine pharmacodynamics : Part II : Crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers 显示文摘 | CORTINEZ L I HSU Y W SUM - PING S T | 2004 | Anesthesiology2004，101，5： | 1 |
| 8 | Photo-Assisted Fenton Mineralization of an Azo-Dye Acid Black Using a Modified Laponite Clay-Based Fe Nanocomposite as a Heterogeneous Catalyst显示文摘 | Sum O S N Feng J Y Hu X J | 2005 | Topics Catal2005，33，4： | 1 |
| 9 | Gqa protein function in vivo: genetic dissection of its role in photoreceptor cell physiology显示文摘 | SCOTT K BECKER A SUM Y | 1995 | Neuron1995，15，： | 1 |
| 10 | Preparation of YBa2 Cu3O7-8 films by MOD method using trifluoroacetate aS precursor显示文摘 | Zhao B Sum Z Y Shi K | 2003 | Physica C2003，386，： | 1 |
| 11 | 显示文摘 | QI Q HA Y Q SUM Y M | 2010 | J Mol Model2010，16，： | 1 |
| 12 | Effect of food reserves on the ratooning growth of rice plant显示文摘 | Iehu M Sum Y | 1983 | Crop Science1983，52，1： | 1 |
| 13 | ' Analysis on multiresolution mosaic images显示文摘 | SUM S WANG L CHENG K Y | 2004 | IEEE Transac- tions on Image Processing2004，13，7： | 1 |
| 14 | Boundary vector for parametric active contours显示文摘 | SUM K W CHEUNG P Y S | 2007 | Pattern Recognition2007，40，6： | 1 |
| 15 | Recovery of metals from electronic scrap 显示文摘 | Sum Elaine Y L | 1991 | JOM1991，43，4： | 1 |
| 16 | White matter abnor- malities in major depression: evidence from post-mortem, neuroimaging and genetic studies显示文摘 | Tham M W Woon P S Sum M Y | 2011 | J Affect Disord2011，132，12： | 1 |
| 17 | Kinetics of esmolol,anultrashort-acting beta blocker,and of its major matabolite显示文摘 | Sum C Y Yacoboi A Kartzinel R | 1993 | Clin Pharmacol Ther1993，34，： | 1 |
| 18 | Investigating the thermodynamic stabilities of hydrogen and methane binary gas hydrates 显示文摘 | Matsumoto Y Grim R G Khan N M Sugahara T Ohgaki K Sloan E D Koh C A Sum A K | 2014 | The Journal of Physical Chemistry C2014，118，7： | 1 |
| 19 | Kinetics of esmolol,an ultra-short-acting beta blocker,and of its major metabolite显示文摘 | Sum C Y Yacobi A Kartzinel R | 1983 | Clin Pharmacol Ther1983，34，4： | 1 |
| 20 | Immunohisto - chemical expression of Bcl - 2, Bax and cytochrome c following focal cerebral ischemia and effect of hypothermia in rat 显示文摘 | Prakasa Babu P Yoshida Y SuM | 2000 | Neurosci Lett2000，，3： | 1 |
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