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| 1 | Arabidopsis Coordinates the Diurnal Regulation of Carbon Allocation and Growth across a Wide Range of Photoperiods显示文摘在短光周期,植物在光更快积累淀粉并且降级它更慢慢地在夜里,保证他们的淀粉储备持续直到黎明。为了调查伴随,在预定生长变化, Arabidopsis 在光周期的一个范围被种并且在黎明和黄昏为插座生物资源,光合作用,呼吸,核糖体丰富,装载的 polysome,淀粉,和超过 40 代谢物分析。数据集合被用来在白天和夜里为生长率建模,并且识别与生长相关的代谢物。建模的生长率并且 polysome 装载在白天并且在在长光周期的夜里高,但是在短光周期在夜里减少了。核糖体丰富在所有光周期是类似的。淀粉的数量怎么在轻时期,夜里的长度,和维护费用积累了,被讨论交往在短光周期在夜里抑制生长,并且为优化核糖体使用改变策略。重要关联在在生长率和糖信号 trehalose 6 磷酸盐和氨基酸生合成中介 shikimate 的层次之间的白天和夜里被发现,识别象在协调生长与的一个网络的中心的这些代谢物日报在碳供应的变化。 | Ronan Sulpice Anna Flis Alexander A. Ivakov Federico Apelt Nicole Krohn Beatrice Encke Christin Abel Regina Feil John E. Lunn Mark Stitt | 2014 | Molecular Plant2014，7，1： | 8 |
| 2 | Pancreatic head cancer in patients with chronicpancreatitis显示文摘BACKGROUND: Chronic pancreatitis (CP) is a risk factor of pancreatic adenocarcinoma (PA). The discovery of a pancreatic head lesion in CP frequently leads to a pancreaticoduo denectomy (PD) which preceded by a multidisciplinary meeting(MM). The aim of this study was to evaluate the relevance between this indication of PD and the definitive pathological results.METHODS: Between 2000 and 2010, all patients with CP who underwent PD for suspicion of PA without any histological proof were retrospectively analyzed. The operative decision has always been made at an MM. The definitive pathological finding was retrospectively confronted with the decision made at an MM, and patients were classified in two groups according to this concordance (group 1) or not (group 2). Clinical and biological parameters were analyzed, preoperative imaging were reread and confronted to pathological findings in order to identify predictive factors of malignant degeneration.RESULTS: During the study period, five of 18 (group 1) patients with CP had PD were histologically confirmed to have PA, and the other 13 (group 2) did not have PA. The median age was52.5 ±8.2 years (gender ratio 3.5). The main symptoms were pain (94.4%) and weight loss (72.2%). There was no patient's death. Six (33.3%) patients had a major complication (ClavienDindo classification ≥3). There was no statistical difference in clinical and biological parameters between the two groups. The rereading of imaging data could not detect efficiently all patients with PA.CONCLUSIONS: Our results confirmed the difficulty in detecting malignant transformation in patients with CP before surgery and therefore an elevated rate of unnecessary PD was found. A uniform imaging protocol is necessary to avoid PD as a less invasive treatment could be proposed. | Aude Merdrignac Laurent Sulpice Michel Rayar Tanguy Rohou Emmanuel Quéhen Ayman Zamreek Karim Boudjema Bernard Meunier | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，2： | 6 |
| 3 | Esophageal perforations显示文摘 | M. Chirica A. Champault X. Dray L. Sulpice N. Munoz-Bongrand E. Sarfati P. Cattan | 2010 | Journal of Visceral Surgery2010，，3： | 3 |
| 4 | Magnetization study of ITER-type internal-Sn Nb3Sn superconducting wire显示文摘 | 张超武 周廉 Andre Sulpice Jean-Louis Soubeyroux Christophe Verwaerde GiaKy Hoang 张平祥 卢亚峰 唐先德 | 2007 | Chinese Physics B2007，16，6： | 3 |
| 5 | 氮素改变辣椒初级代谢和薄壁组织厚度调控比叶面积研究显示文摘比叶面积(SLA)是影响植物光截获和光利用效率的关键性状,常常影响植物的生长和产量。SLA是解释不同植物在不同环境下生长差异的一个关键性状。光照和氮素供应都是决定SLA的重要因素。为了更好地了解辐照度和氮素对辣椒(Capsicum chinense)SLA的影响,研究对两个中国辣椒商品种(Biquinho和Habanero)的初级代谢产物和形态特征进行了分析。两种基因型辣椒的SLA随着遮阴而增加,但随氮供应量的增加而下降;在氮素供应由缺乏到充足的范围内Habanero品种的SLA表现稳定。相关分析表明,高氮供应导致SLA降低是因为氨基酸、蛋白质和淀粉含量的调节,从而影响叶片密度。此外,在中度缺氮到充足供氮范围内,两种基因型辣椒的SLA表现出响应差异,Biquinho和Habanero分别在栅栏和海绵状薄壁组织上表现出差异。总之,结果表明,SLA对氮供应的反应是由某些代谢物含量和依赖于基因型的影响叶片厚度及密度的薄壁组织变化平衡调节的。 | Lucas de ávila Silva Rebeca P.Omena-Garcia Jorge A.Condori-Apfata Paulo Mafra de Almeida Costa Natália Machado Silva Fábio M.Da Matta Agustin Zsogon Wagner L.Araújo Edgard A.de Toledo Picoli Ronan Sulpice Adriano Nunes-Nesi 沈凌峰 吉雪花(译) | 2021 | 辣椒杂志2021，，3： | 2 |
| 6 | Analysis of Short-Term Metabolic Alterations in Arabidopsis Following Changes in the Prevailing Environmental Conditions显示文摘尽管我们有关到相反的 growthconditions 的新陈代谢的调整的重要性的知识的可观的增加最近被提供了,相对,很少对响应 fluctuationin 发生的调整被知道环境因素。评估发生在这样改变环境条件下面的新陈代谢的调整增加我们在是影响 bysuch 的主要小径之间的串音的当前的理解的好机会调节的 offersa。到这个目的,在正常条件下面成长的植物被转移到不同的光,温度 conditionswhich 被期望影响(在另外的过程之中) 光合作用和 photorespiration 和 characterizedat 的率跟随这转变的生理、分子、新陈代谢的层次。我们的结果揭示了类似的行为 inresponse 到处理并且与植物 metabolism.They 的小径进一步加亮的专业一起暗示 photorespiration 的一个紧密的连接这些小径的规定的多数没在叶新陈代谢是的 transcriptionbut 的水平被调停,这相当预先平衡在这些输入 parameters.Key 适应变化词: | Alexandra Florian Zoran Nikoloski Ronan Sulpice Stefan Timm Wagner L. Araujo Takayuki Tohge Hermann Bauwe Alisdair R. Fernie | 2014 | Molecular Plant2014，7，5： | 2 |
| 7 | Enteral Nutrition Reduces Delayed Gastric Emptying After Standard Pancreaticoduodenectomy with Child Reconstruction显示文摘 | Michel Rayar Laurent Sulpice Bernard Meunier Karim Boudjema | 2012 | Journal of Gastrointestinal Surgery2012，，5： | 2 |
| 8 | Mild Reductions in Mitochondrial NAD- Dependent Isocitrate Dehydrogenase Activity Result in Altered Nitrate Assimilation and Piqmentation But Do Not Impact Growth显示文摘 | Agata Sienkiewicz-Porzucek Ronan Sulpice Sonia Osorio Ina Krahnert Andrea Leisse Ewa Urbanczyk-Wochniak Michael Hodges Alisdair R. Fernie Adriano Nunes-Nesi | 2010 | Molecular Plant2010，3，1： | 2 |
| 9 | Cross-talk between the VEGF-A and HGF signalling pathways in endothelial cells显示文摘 | Sulpice E Ding S Muscatelli-Groux B | | 0，，： | 1 |
| 10 | An adiponeclin- like molecule with anfidiabetic pmperties显示文摘 | Sulpice T Pmnet-Marcassus B Molveaux C | | Endocfinology0090，150，10： | 1 |
| 11 | Mild reductions in cytosolic NADP-dependent isocitrate dehydrogenase activity result in lower amino acid contents and pigmentation without impacting growth显示文摘 | Sulpice R Sienkiewicz-Porzucek A Osorio S Krahnert I | 2010 | Amino Acids2010，39，： | 1 |
| 12 | Metabolic endotoxemia initiates obesity and insulin resistance 显示文摘 | Cani PD Amar J Iglesias MA Poggi M Knauf C Bastelica D Neyrinck AM Fava F Tuohy KM Chabo C Waget A Delm6e E Cousin B Sulpice T Chamontin B Ferrieres J Tanti JF Gibson OR Casteilla L Delzenne NM Alessi MC Burcelin R | 2007 | Diabetes2007，56，7： | 1 |
| 13 | The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentia- tion显示文摘 | Wu N Sulpice E Obeid P | 2012 | PLoS One2012，7，45： | 1 |
| 14 | Small interfering RNAs induce target-independent inhibition of tumor growth and vasculature remodeling in a mouse model of hepatocellular carcinoma显示文摘 | BergéM Bonnin P Sulpice E | 2010 | Am J Pathol2010，177，6： | 1 |
| 15 | Molecular profiling of stro- ma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma显示文摘 | Sulpice L Rayar M Desille M | 2013 | Hepatology2013，58，6： | 1 |
| 16 | Epithelial cell adhesion molecule is a prognosis marker for intrahepatic cholangiocarcinoma显示文摘 | Laurent Sulpice Michel Rayar Bruno Turlin Eveline Boucher Pascale Bellaud Mireille Desille Bernard Meunier Bruno Clément Karim Boudjema Cédric Coulouarn | 2014 | Journal of Surgical Research2014，，： | 1 |
| 17 | Enteral nutrition reduces delayed gastric emptying after standard pancreaticoduodenectomy with child reconstruction 显示文摘 | Rayar M Sulpice L Meunier B | 2012 | J Gastrointest Surg2012，16，5： | 1 |
| 18 | Role of peripheral benzodiazepine receptors in mitochondrial, cellular, and cardiac damage induced by oxidative stress and ischemia-reperfusion 显示文摘 | Leducq N Bono F Sulpice T | 2003 | J Pharmacol Exp Ther2003，306，： | 1 |
| 19 | Mild reductions in mitochondrial citrate synthase activity result in a compromised nitrate assimilation and reduced leaf pigmentation but have no effect on photosynthetic performance or growth 显示文摘 | Sienkiewicz-Porzucek A Nunes-Nesi A Sulpice R | 2008 | Plant Physiol2008，147，1： | 1 |
| 20 | RNA interference of LIN5 in tomato confirms its role in controlling brix content, uncovers the influence of sugars on the levels of fruit hormones, and demonstrates the importance of sucrose cleavage for normal fruit development and fertility显示文摘 | Zanor M I Osorio S Nunes - Nesi A Carrari F Lohse M Usadel B Ktihn C Blelss W Giavahsco P Wi|imitzer L Sulpice R Zhou YH and Fernie AR | 2009 | Plant Physiol2009，150，7： | 1 |
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