4篇
您的检索式：作者名="Sudarshini"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Single-cell approaches to investigate B cells and antibodies in autoimmune neurological disorders显示文摘Autoimmune neurological disorders,including neuromyelitis optica spectrum disorder,anti-N-methyl-D-aspartate receptor encephalitis,anti-MOG antibody-associated disorders,and myasthenia gravis,are clearly defined by the presence of autoantibodies against neurological antigens.Although these autoantibodies have been heavily studied for their biological activities,given the heterogeneity of polyclonal patient samples,the characteristics of a single antibody cannot be definitively assigned.This review details the findings of polyclonal serum and CSF studies and then explores the advances made by single-cell technologies to the field of antibody-mediated neurological disorders.High-resolution single-cell methods have revealed abnormalities in the tolerance mechanisms of several disorders and provided further insight into the B cells responsible for autoantibody production.Ultimately,several factors,including epitope specificity and binding affinity,finely regulate the pathogenic potential of an autoantibody,and a deeper appreciation of these factors may progress the development of targeted immunotherapies for patients.Access options. | Alicia Zou Sudarshini Ramanathan Russell C.Dale Fabienne Brilot | 2021 | Cellular & Molecular Immunology2021，18，2： | 4 |
| 2 | Isolation,char-acterization and evolution of NBS-LRR encoding disease-resistance gene analogsin eggplant against bacterial wilt显示文摘 | ANAND C R SUDARSHINI V S ASWATH C | 2015 | European Journal of Plant Pathology2015，143，3： | 1 |
| 3 | Development and initial validation of a scale to measure emotional abuse among school children aged 13-15 years in Sri Lanka显示文摘 | Sudarshini F Dulitha F | 2003 | Child Abuse and Neglect2003，27，： | 1 |
| 4 | Autoimmune encephalitis: Recent updates and emerging challenges显示文摘 | Sudarshini Ramanathan Shekeeb S. Mohammad Fabienne Brilot Russell C. Dale | 2013 | Journal of Clinical Neuroscience2013，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员