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| 1 | Voxel-based magnetic resonance imaging investigation of poor and preserved clinical insight in people with schizophrenia显示文摘AIM To define regional grey-matter abnormalities in schizophrenia patients with poor insight(Insight-),relative to patients with preserved clinical insight(Insight+),and healthy controls.METHODS Forty stable schizophrenia outpatients(20 Insight-and 20 Insight+) and 20 healthy controls underwent whole brain magnetic resonance imaging(MRI).Insight in all patients was assessed using the Birchwood Insight Scale(BIS;a self-report measure).The two patient groups were preselected to match on most clinical and demographic parameters but,by design,they had markedly distinct BIS scores.Voxel-based morphometry employed in SPM8 was used to examine group differences in grey matter volumes across the whole brain.RESULTS The three participant groups were comparable in age [F(2,57) = 0.34,P = 0.71] and the patient groups did not differ in age at illness onset [t(38) = 0.87,P = 0.39].Insight-and Insight+ patient groups also did not differ in symptoms on the Positive and Negative Syndromes scale(PANSS):Positive symptoms [t(38) = 0.58,P = 0.57],negative symptoms [t(38) = 0.61,P = 0.55],general psychopathology [t(38) = 1.30,P = 0.20] and total PANSS scores [t(38) = 0.21,P = 0.84].The two patient groups,as expected,varied significantly in the level of BIS-assessed insight [t(38) = 12.11,P < 0.001].MRI results revealed lower fronto-temporal,parahippocampal,occipital and cerebellar grey matter volumes in Insightpatients,relative to Insight+ patients and healthy controls(for all clusters,family-wise error corrected P < 0.05).Insight+ patient and healthy controls did not differ significantly(P > 0.20) from each other.CONCLUSION Our findings demonstrate a clear association between poor clinical insight and smaller fronto-temporal,occipital and cerebellar grey matter volumes in stable long-term schizophrenia patients. | Adegboyega Sapara Dominic H Ffytche Michael A Cooke Steven CR Williams Veena Kumari | 2016 | World Journal of Psychiatry2016，6，3： | 3 |
| 2 | Identification of two inde- pendent risk factors for lupus within the MItE in United Kingdom fami- lies显示文摘 | Fernando MM Stevens CR Sabeti PC | 2007 | PLoS Genet2007，3，11： | 1 |
| 3 | Modified low den sity lipoprotein and eytokines mediate moneyte adhesion to smooth muscle cells 显示文摘 | Thome SA Abbot SE Stevens CR | 1996 | Atherosclerosis1996，127，： | 1 |
| 4 | Antiretroviral prophylaxis for HIV prevention in heterosexual men and women 显示文摘 | Baeten JM Donnell D Ndase P Mugo NR Campbell JD Wangisi J Tappero JW Bukusi EA Cohen CR Katabira E Ronald A Tumwesigye E Were E Fife KH Kiarie J Farquhar C John-Stewart G Kakia A Odoyo J Mucungu- zi A Nakku-Joloba E Twesigye R Ngure K Apaka C Tamooh H Gabona F Mujugira A Panteleeff D Thomas KK Kidoguchi L Krows M Revall J Morrison S Haugen H Emmanuel-Ogier M Ondrejcek L Coombs RW Fren- kel L Hendrix C Bumpus NN Bangsberg D Haberer JE Stevens WS Lingappa JR Celum C Partners PrEP Study Team | 2012 | N Engl J Med2012，367，5： | 1 |
| 5 | Extracellular signal - regulated kinase activation and endothelin - 1 production in human endothelial cells exposed to vibration显示文摘 | White CR Haidekker MA Stevens HY | 2004 | J Phys- iol2004，555，2： | 1 |
| 6 | Effects of selective and nonselective nonsteroidal anti-inflammatory drugs on anti- biotic efficacy of experimental group A streptococcal myone crosis显示文摘 | Hamilton SM Bayer CR Stevens DL | 2014 | J Infect Dis2014，209，9： | 1 |
| 7 | Catheter - related bacteremia due to Roseomonas species in pediatric hematology/oncology patients 显示文摘 | McLean TW Rouster - Stevens K Woods CR | 2006 | Pediatric Blood Cancer2006，46，4： | 1 |
| 8 | Neural responses to sad facial expressions in major depression following cognitive behavioral therapy显示文摘 | Cynthia HY Fu Steven CR | 2008 | Biol Psychiatry2008，64，： | 1 |
| 9 | Defning the role ofthe MHC in autoimmunity : a review and pooled analysis显示文摘 | Fernando MM Stevens CR Walsh EC | 2008 | PLoSGenet2008，4，10： | 1 |
| 10 | Modified low density lipoprotein and cytokines mediate monocyte adhesion to smooth muscle cells显示文摘 | THORNE SA ABBOT SE STEVENS CR | 1996 | Atherosclerosis1996，127，2： | 1 |
| 11 | Modified low density lipoprotein and cytokines mediate monocyte adhesion to smooth muscle cells显示文摘 | Thorne SA Abbot SE Stevens CR | 1996 | Atherosclerosis1996，127，2： | 1 |
| 12 | Rigidity of tracheae and bronchi during muscular constriction显示文摘 | Olsen CR Stevens AE Mcllroy MB | 1967 | J Appl Physiol1967，23，1： | 1 |
| 13 | Attenuation of the neural response to sad faces in major depression by antidepressant treatment: A prospective, event - related functional magnetic resonance imaging study显示文摘 | Cynthia HY Steven CR Cleare AJ | 2004 | Arch Gen Psychiatry2004，61，： | 1 |
| 14 | Modified low density lipopeotein and eytokines mediate monocyte adhesion to smooth muscle cells显示文摘 | Thorne SA Abbot SE Stevens CR | 1996 | Atherosclerosis1996，127，2： | 1 |
| 15 | Modified low density lipoprotein and cytokines mediate monocyte adhe- sion to smooth muscle cells 显示文摘 | Thome SA Abbot SE Stevens CR | 1996 | Atherosclerosis1996，127，2： | 1 |
| 16 | Modified low density lipoprotein and cytokine mediate monocyte adhesion to smooth muscle cells显示文摘 | Thorne SA Abbot SE Steven CR | 1996 | Atherosclerosis1996，127，2： | 1 |
| 17 | 建设恢复力和适应性以对付北极的变化显示文摘人类行为引起的空前的全球变化挑战着社会支撑我们这颗行星保持自身优点的能力。这就要求对变化进行主动的管理以培养地球的恢复力——维持在变化的情况下对社会很重要的一些属性,和适应性——发展新的社会生态构造以便在新的条件下有效地发挥作用。北极的广大地区仍然完整地保留着原型的生态及社会过程及反馈,这为我们为变化预先做出计划提供了可能是最后一个实验的机会。如果该策略的可行性在北极可以被证实,我们对于变化的动态所得到的进一步的理解就可以实施到那些被人类较大地改变了的地区中。现在执行管理北极变化的政策的条件可能很理想,因为近来的研究提供了极其重要的科学知识,合适的国际机制也已各就各位,而且,如果北极地区的国家选择这样做的话,他们具备实行必要改变的财力。 | F.Stuart Chapin Ⅲ Michael Hoel Steven R.Carpenter Jane Lubchenco Brian Walker Terry V.Callaghan Carl Folke Simon A.Levin Karl-Gran Mler Christer Nilsson Scott Barrett Fikret Berkes Anne-Sophie Crépin Kjell Danell Thomas Rosswall David Starrett Anastasios Xepapadeas Sergey A.Zimov 陈卓天 | 2006 | AMBIO-人类环境杂志2006，35，4： | 1 |
| 18 | PAHdb 2003:what a locus - specific knowledgebase can do显示文摘 | Scriver CR Hurtubise M Konecki D Phommarinh M Prevost L Erlandsen H Steven H Stevers R Waters PJ Ryan S McDonald D Sarkissian C | 2003 | Hum Mutat2003，21，： | 1 |
| 19 | Catheter related bacteremia due to Roseomonas species in pediatric hematology/oncology patients显示文摘 | McLean TW Rouster - Stevens K Woods CR | 2006 | Pediatr Blood Cancer2006，46，4： | 1 |
| 20 | Electronic reverse auction configuration and its impact on buyer price and supplier perceptions of opportunism: A laboratory experiment 显示文摘 | Carter CR Stevens CK | 2007 | Journal of Operations Management2007，25，： | 1 |
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