|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Metastatic type 1 gastric carcinoid:A real threat or just a myth?显示文摘AIM:To describe disease characteristics and treatment modalities in a group of rare patients with metastatic gastric carcinoid type 1(GCA1).METHODS:Information on clinical,biochemical,radiological,histopathological findings,the extent of the disease,as well as the use of different therapeutic modalities and the long-term outcome were recorded.Patients’data were assessed at presentation,and thereafter at 6 to 12 monthly intervals both clinically and biochemically,but also endoscopically and histopathologically.Patients were evaluated for the presence of specific symptoms;the presence of autoimmune disorders and the presence of other gastrointestinal malignancies in other family members were also recorded.The evaluation of response to treatment was defined using established WHO criteria.RESULTS:We studied twenty consecutive patients with a mean age of 55.1 years.The mean follow-up period was 83 mo.Twelve patients had regional lymph node metastases and 8 patients had liver metastases.The primary tumor mean diameter was 20.13±10.83mm(mean±SD).The mean Ki-67 index was 6.8%±11.2%.All but one patient underwent endoscopic or surgical excision of the tumor.The disease was stable in all but 3 patients who had progressive liver disease.All patients remained alive during the follow-up period.CONCLUSION:Metastatic GCA1 carries a good overall prognosis,being related to a tumor size of≥1 cm,an elevated Ki-67 index and high serum gastrin levels. | Simona Grozinsky-Glasberg Dimitrios Thomas Jonathan R Strosberg Ulrich-Frank Pape Stephan Felder Apostolos V Tsolakis Krystallenia I Alexandraki Merav Fraenkel Leonard Saiegh Petachia Reissman Gregory Kaltsas David J Gross | 2013 | World Journal of Gastroenterology2013，19，46： | 11 |
| 2 | 两种新型骨水泥的组织学和生物力学研究显示文摘我们研制了两种可被骨长入的骨水泥:一种是部分可吸收的骨水泥(PRC),以双酚α-甲基丙烯酸甘油酯(Bis-GMA)为基质,混合硅铝陶瓷和可吸收性聚合体颗粒调制成;另一种是磷酸钙骨水泥(CPC),由磷酸三钙、一水磷酸二氢钙、二水磷酸二钙和黄原胶组成。将这两种骨水泥分别植入家兔股骨和胫骨髁的骨缺损中,植入后2、4、12和24周取材,进行组织学观察和生物力学测试。结果发现,CPC组有递增的骨整合,伴有生物降解及巨噬细胞出现,力学测试显示抗压强度在4周之前一直降低,4周后才轻微升高,弹性模量随时间普遍降低。到第4周时,组织学观察还发现新生骨与CPC边缘直接接触。整个观察过程中未发现炎症反应。PRC组,骨整合及生物降解都很轻微,但在各个观察阶段,其抗压强度比松质骨和CPC组高(p<0.05),在4周之前,它的弹性模量高于松质骨和CPC组,4周后低于松质骨。(Bone 25:41S--45S;1999)。 | 卢建熙 I ABOUT G STEPHAN P VAN LANDUYT J DEJOU M FIOCCHI J LEMAITRE J-P PROUST | 2000 | 医用生物力学2000，15，3： | 10 |
| 3 | Immunogenetic phenotypes in inflammatory bowel disease显示文摘当前接受的 etiopathogenic 假设建议长期的肠的发炎和煽动性的肠疾病(IBD ) 的相关全身的表明特征由于对居民钠的过分好攻击或病理学的有免疫力的回答细菌的成分。预先安排的因素是粘膜免疫者回答或障碍功能的基因 dysregulation,与环境刺激触发的发作。这些因素和他们的相互作用可以也是疾病显型和疾病前进的重要决定因素。免疫的出现基因显型把支持借给不同免疫者处理的危险性基因调整的建议假设,由钠抗原开车,表示了接着在 IBD 影响临床的显型的同样特定的有免疫力的显型病人。 | Maria C Dubinsky Kent Taylor Stephan R Targan Jerome I Rotter | 2006 | World Journal of Gastroenterology2006，12，23： | 4 |
| 4 | Loss of the tissue- specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma 显示文摘 | Sturm I Stephan C Gillissen B | 2006 | Cell Death Differ2006，13，4： | 1 |
| 5 | Matrix metalloproteinase expression in tumor invasion and metastasis显示文摘 | Stephanic C Graeme I | 1999 | Pathol1999，189，3： | 1 |
| 6 | Particle size distribution of organic primary and secondary aerosol constituents in urban,background marine,and forest atmosphere显示文摘 | KAVOURAS I G STEPHANOU E G | 2002 | Geophysical Research2002，107，8： | 1 |
| 7 | Alkaline PF Resins Linear Ex- tension by Urea Condensation with Hydroxybenzylalcohol Groups 显示文摘 | Pizzi A Stephanou A Antunes I | 1993 | Journal of Applied Polymer Science1993，50，12： | 1 |
| 8 | Material resistance of flame retarded wood-plastic composites against fire and fungal decay显示文摘 | Naumann A Seefeldt H Stephan I | 2012 | Polymer Degradation and Stability2012，97，9： | 1 |
| 9 | Constitutively active SHP2cooperates with HoxA10 overexpression to induce acute myeloid leuke-mia显示文摘 | Wang H Stephan L Konieczna I | 2009 | J Biol Chem2009，284，4： | 1 |
| 10 | Alkaline PF resins linear extension by urea condensation with hydroxybenzyalchohol groups显示文摘 | PIZZI A STEPHANOU A ANTUNES I | 1993 | J Appl Polym Sci1993，50，： | 1 |
| 11 | Iso-and anteiso-alkanes: specific tracers of environmental tobacco smoke in indoor and outdoor particle-size distributed urban aerosols显示文摘 | Kavouras I G Stratigakis N Stephanou E G | 1998 | Enviromnental Science and Technology1998，32，10： | 1 |
| 12 | Material resistance of weathered wood-plastic composites against fungal decay显示文摘 | Naumann A Stephan I Noll M | 2012 | International Biodeterioration&Biodegradation2012，75，1： | 1 |
| 13 | Characterization of single wailed carbon nanotubes - PMMA composites显示文摘 | Stephan C Nguyen T P Chape I M L | 2000 | Synthetic Metals2000，108，： | 1 |
| 14 | Formation of atmospheric particles from organic acids produced by forests显示文摘 | Kavouras I G Mihalopoulos N Stephanou E | 1998 | Nature1998，395，： | 1 |
| 15 | Alkaline PF resins linear ex-tension by urea condensation with hydroxybenzyelcohol groups 显示文摘 | Pizzi A Stephanou A Antunes I | 1993 | Journal of Applied Polymer Sciences1993，50，12： | 1 |
| 16 | Iso-and anteiso-alkanes:specific tracers of environmental tobacco smoke in indoor and outdoor particle-size distributed urban aerosols显示文摘 | Kavouras I G Stratigakis N Stephanou E | 1998 | Environmental Science Technology1998，32，10： | 1 |
| 17 | Drotrecogin alfa(activated)for the treatment of meninggococcal purpura fulminans 显示文摘 | Esther B Stephan B Roland I | 2003 | Crit Care Med2003，29，： | 1 |
| 18 | Comparison of eight clinical rating scales used for the assessment of MPTP- induced parkinsonism in the Macaque monkey 显示文摘 | Christelle I Erwan B Stephane G | 2000 | J Neuroscience Methods2000，96，： | 1 |
| 19 | A Genetic Local Search Algorithm for Minimizing Total Weighted Tardiness in the Job-shop Scheduling Problem 显示文摘 | Essafi I Mati Y Stephane D P | 2008 | Computers & Operations Research2008，35，8： | 1 |
| 20 | A test of the treeline carbon limitation hypothesis by in situ CO2 enrichment and defoliation显示文摘 | I TANYA HANDA CHRISRIAN KORNER STEPHAN HATTENSCHWILER | 2005 | Ecology2005，86，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员