|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Predictive value of early atrial tachyarrhythmias recurrence after circum- ferential anatomical pulmonary vein ablation 显示文摘 | Bertaglia E Stable G Senatore G | 2005 | PACE2005，28，5： | 1 |
| 2 | Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy显示文摘 | Goulden V Stables G | 2005 | Br J Dermatol2005，153，4： | 1 |
| 3 | Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy显示文摘 | Goulden V Stables G | 2005 | Br J Dermatol2005，153，4： | 1 |
| 4 | Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy显示文摘 | Bfitton JE Goulden V Stables G | 2005 | Br J Dermatol2005，153，4： | 1 |
| 5 | Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy显示文摘 | Britton JE Goulden V Stables G | 2005 | Br J Dermatol2005，153，4： | 1 |
| 6 | Localization of transforming growth factor-alpha RNA and protein in the skin of psoriatic patients receiving therapy显示文摘 | WATTS P STABLES G S AKHURST R J | 1994 | Br J Dermatol1994，131，1： | 1 |
| 7 | Evaluation of a stimulus- response method for distinguishing out-migrant salmonids from drifting debris for sonar counts in the Trinity River, California显示文摘 | Stables T B Kautsky G A | 2000 | Aquatic Living Resources2000，13，5： | 1 |
| 8 | Pigmented fibroepithelioma of Pinkus显示文摘 | Strauss R Edwards S Stables G | 2004 | Br J Dermatol2004，150，： | 1 |
| 9 | Market Orientation at the Top 200 British Charity Organizations and Its Impact on Their Performance显示文摘 | BALABANIS G STABLES R PHILLIPS H | 1997 | European Journal of Marketing1997，31，8： | 1 |
| 10 | Prevalence of facial acne in adults显示文摘 | Goulden V Stables G I Cunliffe W J | 1999 | J Am Aacad Dermatol1999，41，4： | 1 |
| 11 | Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy显示文摘 | Britton JE Goulden V Stables G | 2005 | Br J Dermato12005，153，： | 1 |
| 12 | Investigation of theuse of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic acid phototherapy显示文摘 | Britton JE Goulden V Stables G | 2005 | Br J Dermatol2005，153，4： | 1 |
| 13 | CD2-associated protein and glomerular disease显示文摘 | WOLF G STABL R A | 2003 | Lancet2003，362，9397： | 1 |
| 14 | In- creased levels of advanced glycation end products in human eataractous lenses显示文摘 | Franke S Dawezyuski J Strobel J Niwa T Stabl P Stein G | 2003 | J Cataract Refract Surg2003，29，5： | 1 |
| 15 | Market Orientation at the Top 200 British Charity Organizations and Its Impact on Their Performance显示文摘 | Balabanis G Stables R Phillips H | 1997 | European Journal of Marketing1997，31，8： | 1 |
| 16 | 5-氨基酮戊酸光疗法中采用脉冲式染料激光器治疗Bowen病的研究显示文摘Background: The use of 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) for the treatment of Bowen’s disease is well established. However, treatment w ith a continuous light source has the disadvantage of prolonged treatment time d uring which patients often experience significant discomfort requiring the use o f local anaesthetic. Objectives: The aim of this study was to assess the efficac y and safety of the pulsed dye laser (PDL)as the light source for photoactivatio n of the protoporphyrin IX to treat Bowen’s disease by PDT. Methods: Thirteen p atients with a total of 17 patches of histologically proven Bowen’s disease wer e treated with 20%5-ALA in Unguentum M(r) (Crookes Healthcare, Nottingham, U.K .) under occlusion for 4 h. The patches were then irradiated using a Candela SPL TL-1b (Candela Corporation, Wayland, MA, U.S.A.) PDL using a wavelength of 585 nm, with a 7-mm diameter spot at a fluence of 10 J cm-2. The spots overlapped by 50%to cover the lesion and extend beyond the clinical margin of the patch of Bowen’s disease by 0.5 cm. Patients were then followed up initially at 2 month s, then at 3-monthly intervals for a period of 12 months to assess treatment su ccess and recurrence rate. Results: Subjects consisted of 10 females and three m ales, between 47 and 88 years. The mean area of the patches of Bowen’s disease was 315.4 mm2 (range 36-2464 mm2) requiring a median of 32 pulses (range 3-260 ). Lesions sites were hands (two), foot (one) and lower leg (14). All patients e xperienced varying degrees of discomfort during treatment but none required the use of local anaesthetic. At 2 months eight treatment sites could not be assesse d due to loose overlying crusts and removal of these revealed superficial erosio ns in seven patients. Of the 17 lesions treated, on follow-up at 1 year, 14 pat ches (82%) demonstrated a complete clinical response, although one of these had required a second treatment. Two patients with three lesions that would have re quired further therapy refused a second treatment. Prolonged crusting lasting 8 weeks occurred in eight patches and prolonged discomfort lasting 6 weeks occurre d in four patients. Conclusions: This study has shown that the PDL is an effecti ve light source for ALA-PDT of Bowen’s disease. Light source exposure times are shorter, although overall treatment time may not always be significantly reduce d for larger lesions. The procedure was well tolerated. However, the post-treat ment morbidity was relatively high compared with the more conventional treatment modalities. Further studies are needed to determine whether lower energy fluenc es can maintain similar efficacy while reducing post-treatment morbidity. | Britton J.E.R Goulden V Stables G 李政霄 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，0，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员