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| 1 | 基于定量宏基因组学评估肝硬化患者肠道菌群的变化与慢加急性肝衰竭及预后的关系显示文摘【据Gastroenterology 2020年9月报道】题:基于定量宏基因组学评估肝硬化患者肠道菌群的变化与慢加急性肝衰竭及预后的关系(作者SoléC等)肝硬化与肠道菌群组成的改变有关。慢加急性肝衰竭(ACLF)是肝硬化最严重的临床阶段,但目前仍缺乏使用定量宏基因组学研究ACLF中肠道菌群改变的信息。 | SOLéC GUILLY S Da SILVA K 邵玥明 温晓玉 | 2020 | 临床肝胆病杂志2020，36，11： | 4 |
| 2 | 文献快报(4):童年期不良经历与成年期生理损害的关系--1958年英国出生队列研究显示文摘适应负荷(allostatic load,AL)是一种衡量躯体受到长期压力时所导致生理损害程度的评价工具,这种损害可能部分是由于生命早期不良经历所致,因此这个指标通常可作为评价慢性应激暴露水平的生物标志物。Barboza Solís C等通过对童年期不良经历(adverse childhood experiences,ACEs)与中年期适应负荷关系的研究来进一步验证远期不良经历可导致生理功能损害的研究假设。该课题组利用1958年英国出生队列,其中女性3 782人,男性3 753人,共随访了7次。在儿童7岁、11岁和16岁时分别调查了童年期不良经历;在队列人群44岁时,采用神经内分泌系统、免疫与炎症系统、代谢系统、呼吸与心血管系统4个系统14个指标作为评价其适应负荷的可操作性指标,同时调查了健康行为、 | BARBOZA SOLíS C KELLY-IRVING M FANTIN R 苏普玉 | 2015 | 中国学校卫生2015，36，3： | 3 |
| 3 | A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity显示文摘Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and,thus,for public health policy and vaccine development for COVID-19.In this study,using either live SARS-CoV-2 particles or retroviruses pseudotyped with the SARS-CoV-2 S viral surface protein(Spike),we studied the neutralizing antibody(nAb)response in serum samples from a cohort of 140 SARS-CoV-2 qPCR-confirmed infections,including patients with mild symptoms and also more severe forms,including those that required intensive care.We show that nAb titers correlated strongly with disease severity and with anti-spike IgG levels.Indeed,patients from intensive care units exhibited high nAb titers;conversely,patients with milder disease symptoms had heterogeneous nAb titers,and asymptomatic or exclusive outpatient-care patients had no or low nAbs.We found that nAb activity in SARS-CoV-2-infected patients displayed a relatively rapid decline after recovery compared to individuals infected with other coronaviruses.Moreover,we found an absence of cross-neutralization between endemic coronaviruses and SARS-CoV-2,indicating that previous infection by human coronaviruses may not generate protective nAbs against SARS-CoV-2.Finally,we found that the D614G mutation in the spike protein,which has recently been identified as the current major variant in Europe,does not allow neutralization escape.Altogether,our results contribute to our understanding of the immune correlates of SARS-CoV-2-induced disease,and rapid evaluation of the role of the humoral response in the pathogenesis of SARS-CoV-2 is warranted. | Vincent Legros Solène Denolly Manon Vogrig Bertrand Boson Eglantine Siret Josselin Rigaill Sylvie Pillet Florence Grattard Sylvie Gonzalo Paul Verhoeven Omran Allatif Philippe Berthelot Carole Pélissier Guillaume Thiery Elisabeth Botelho-Nevers Guillaume Millet Jérôme Morel Stéphane Paul Thierry Walzer François-Loïc Cosset Thomas Bourlet Bruno Pozzetto | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 4 | Embryo- growth rate and duration in sunflower as affected by tem- perature显示文摘 | CHIMENTI C A Hall A J SOL LOAPEZ M | 2001 | Field Crops Research2001，69，： | 1 |
| 5 | Hallux valgus in heritance:pedigree research in 350 patients with bunion deformity显示文摘 | Piqu-vidal C Sol MT Antich J | 2007 | J Foot Ankle Surg2007，46，3： | 1 |
| 6 | Methanol electro-oxidation on unsupported Pt-Ru alloys at different temperature 显示文摘 | DERYN C SOL G | 2002 | J Electrochemical Soc2002，143，： | 1 |
| 7 | Effect of drainage area on hypsometry from an analysis of small-scale drainage basins in the Siwalik Hills (central Nepal)显示文摘 | Hurtrez J E Sol C Lucazeau F | | 0，，： | 1 |
| 8 | Hallux valgus in-heritance:pedigree research in 350 patients with bunion deformity显示文摘 | Piqu-Vidal C Sol MT Antich J | 2007 | J Foot Ankle Surg2007，46，3： | 1 |
| 9 | Rapid and simple method for purification of nucleic acids显示文摘 | Boom R Sol C J Salimans M M | 1990 | J Clin Microbiol1990，28，3： | 1 |
| 10 | Rapid and simple method for purification of nucleic acids显示文摘 | Boom R Sol C J Salimans M M | 1990 | J Clin Microbiol1990，28，3： | 1 |
| 11 | Heavy metal accumulation in plants and soil irrigated with wastewater from mexico city显示文摘 | MIRELES A SOLS C ANDRADE E | 2004 | Nuclear Instruments and Methods in Physics Research2004，，6： | 1 |
| 12 | Effects of chronic acarbose treatment on adipocyte insulin responsiveness, serum levels of leptin and adiponectin and hypothalamic NPY expression in obese diabetic Wistar rats显示文摘 | Perez C Fern a ndez-Agull o T De Sol i s AJ | 2008 | Clin Exp Pharmacol Physiol2008，35，3： | 1 |
| 13 | Effect and drainage area on hypsornetry from an analysis of small-scale drainage basins in the Siwalik hills( Central Nepal)显示文摘 | HURTREZ J E SOL C LUCAZEAU F | 1999 | Earth Surface Processes and Landforms1999，24，9： | 1 |
| 14 | Rapid and simple method for purification of nucleic acids显示文摘 | Boom R Sol C J Salimans M M | 1990 | J Cli Microbiol1990，28，3： | 1 |
| 15 | Perturbation of membrane dynamics in nerve cells as an early event during bilirubin-induced apoptosis显示文摘 | Rodrigues C M Sol S Castro R E | 2002 | J Lipid Res2002，43，6： | 1 |
| 16 | Rapid and simple method for purification of nucleic acids显示文摘 | Boom R C J A Sol M M M Salimans | 1990 | Journal of Clinical Microbiology1990，28，： | 1 |
| 17 | Rapid and simple methods for purification ofnucleic acid 显示文摘 | Boom R Sol C J A Salimans M M M | 1990 | J Clin Microbiol1990，28，： | 1 |
| 18 | Rapid and simple method for purification of nucleic acids显示文摘 | Boom R C J Sol M M Salimans | 1990 | J Clin Microbiol1990，28，： | 1 |
| 19 | Effect of drainage area on hypsometry from an analysis of small-scale drainage basins in the Siwalik Hills(central Nepal)显示文摘 | Hurtrez J E Sol C Lucazeau F | 1999 | Earth Surface Processes and Landorms1999，328，： | 1 |
| 20 | Renal bioposy findings in Belgium:a retrospective single center analysis 显示文摘 | Mesquita M Fosso C Bahoto Sol E | 2011 | Axta Clin Belg2011，66，2： | 1 |
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