|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2018加拿大心境障碍与焦虑障碍治疗协作组/国际双相障碍学会指南:双相障碍的管理显示文摘加拿大心境障碍与焦虑障碍治疗协作组(Canadian Network for Mood and Anxiety Treatments,CANMAT)曾于2005年发布了第1版双相障碍管理指南,并分别于2007、2009和2013年对该指南进行了更新,其中最近的2次更新是与国际双相障碍学会(International Society for Bipolar Disorders,ISBD)合作完成。2018版CANMAT/ISBD双相障碍治疗指南(以下简称指南)反映了自2005年首版指南发表以来本领域取得的重大进展,包括疾病诊断与疾病管理的更新以及药物治疗与心理治疗的近期研究进展。这些前沿进展中综合考虑了循证证据的级别,并基于治疗疗效、临床实践经验、安全性、耐受性和药物导致的转相风险等,对一线、二线及三线治疗方案进行了简明而清晰的推荐。本指南中新增内容涵盖了双相Ⅰ型障碍(BD-Ⅰ)的躁狂发作急性期、抑郁发作急性期和双相障碍维持期的一线及二线治疗推荐等级划分。这种对治疗推荐等级的划分综合考虑了治疗方法对双相障碍不同时相的影响,将进一步帮助临床医生做出基于循证证据的治疗决策。锂盐、喹硫平、双丙戊酸盐、阿塞那平、阿立哌唑、帕利哌酮、利培酮和卡利拉嗪单药或联合使用被推荐为躁狂发作急性期的一线治疗选择。BD-Ⅰ抑郁期的一线治疗选择包括喹硫平、鲁拉西酮、锂盐、拉莫三嗪单药,鲁拉西酮联合锂盐或双丙戊酸盐或拉莫三嗪辅助治疗。尽管急性期治疗有效的药物通常应继续用于BD-Ⅰ的维持期治疗,但也存在一些特殊情况(例如抗抑郁药)。现有数据表明,锂盐、喹硫平、双丙戊酸盐、拉莫三嗪、阿塞那平和阿立哌唑单药或联合治疗应被视为维持治疗的初始或更换治疗方案时的一线选择。除了探讨BD-Ⅰ的相关问题外,本指南中还对双相Ⅱ型障碍(BD-Ⅱ)的临床管理进行了系统回顾并给予治疗推荐,同时针对特殊人群也有相关推荐,如处于各个生殖周期的女性、儿童、青少年和老年人。此外,本指南中还讨论了特定精神疾病及共病(如物质滥用、焦虑障碍和代谢性疾病)的影响。最后,本指南中概述了安全性和药物监测的相关问题。CANMAT/ISBD工作组希望本指南能够成为全球临床医生的实用工具。 | Lakshmi N Yatham Sidney H Kennedy Sagar V Parikh Ayal Sehaffer David J Bond Benicio N Frey Verinder Sharma Benjamin I Goldstein Soham Rej Serge Beaulieu Martin Alda Glenda MaeQueen Roumen V Milev Arun Ravindran Claire O'Donovan Diane Mclntosh Raymond W Lam Gustavo Vazquez Flavio Kapczinski Roger S Melntyre Jan Kozicky Shigenobu Kanba Beny Lafer Trisha Suppes Joseph R Calabrese Eduard Vieta Gin Malhi Robert M Post Michael Berk 胡晨(译) 王刚(译) | 2019 | 中华精神科杂志2019，52，1： | 25 |
| 2 | Diagnostic efficacy of Ziehl-Neelsen method against fluorescent microscopy in detection of acid fast bacilli显示文摘Objective:To investigate the application of Ziehl-Neelsen(Z-N) and fluorescent microscopy in detection of acid fast bacilli(AFB).Methods:Duplicate smears were prepared from 260 sputum samples and stained with Z-N and fluorescent staining(FS) methods.The efficiency of both methods in primary diagnosis of tuberculosis were evaluated.Results:The smears were positive for AFB in 15(5.77%) samples by Z-N staining method and in 16(6.15%) samples by FS method.The sensitivity and specificity of Z-N staining method against FS method were 93.75% and 100%respectively.Conclusions:Though lesser cost-effective than Z-N,FS method is a more sensitive and better case finding tool in detection of AFB. | Soham Gupta Vishnu Prasad Shenoy Indira Bairy Muralidharan S | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，4： | 3 |
| 3 | Amniotic fluid: Source of trophic factors for the developingintestine显示文摘The gastrointestinal tract(GIT) is a complex system, which changes in response to requirements of the body. GIT represents a barrier to the external environment. To achieve this, epithelial cells must renew rapidly. This renewal of epithelial cells starts in the fetal life under the influence of many GIT peptides by swallowing amniotic fluid(AF). Development and maturation of GIT is a very complex cascade that begins long before birth and continues during infancy and childhood by breastfeeding. Many factors like genetic preprogramming, local and systemic endocrine secretions and many trophic factors(TF) from swallowed AF contribute and modulate the development and growth of the GIT. GIT morphogenesis, differentiation and functional development depend on the activity of various TF in the AF. This manuscript will review the role of AF borne TF in the development of GIT. | Soham Dasgupta Shreyas Arya Sanjeev Choudhary Sunil K Jain | 2016 | World Journal of Gastrointestinal Pathophysiology2016，7，1： | 2 |
| 4 | Agent-oriented programming 显示文摘 | Soham Y | 1993 | Artificial Intelligence1993，60，1： | 1 |
| 5 | Calculating economy -wide energy intensity decline rate: The role of sectoral output and energy shares显示文摘 | SOHAM BAKSI CHRIS GREEN | 2007 | Energy Policy2007，，35： | 1 |
| 6 | A magnetorheological actuation system: Test and model 显示文摘 | SOHAMED J CETTEY A MARWALA N | 2008 | Smart Material and Structure2008，17，： | 1 |
| 7 | Tinospora cordifolia: One plant, many roles显示文摘 | Soham Saha Shyamasree Ghosh | 2012 | Ancient Science of Life2012，，4： | 1 |
| 8 | Diabetes mellitus exac- erbates motor and sensory impairment in CMT1A显示文摘 | Soham Sheth Kevin Francies Carly E | 2008 | J Peripher Nerv Syst2008，13，4： | 1 |
| 9 | Shifting of research trends in islanding detection method-a comprehensive survey显示文摘The augmentation in electricity demand,power system privatization as well as efficacy of renewable resources has paved the way for power system companies and researchers to exploit the field of grid connected distributed generation(DG)and its issues,islanding being a dominant one.Several research works have been conducted to mitigate the issues of islanding detection(ID).In context of this,the paper gives a comprehensive review of islanding issues,standard test systems,criteria and shifting of research trends in islanding detection methods(IDMs).The significant contributions pertain to categorization of IDMs,evaluation of non-detection zone(NDZ)for each test system,disquisition on evolution and advancement of IDMs and its comparisons based on criteria such as NDZ,run on time,nuisance tripping percentage,applicability in multi DG system and implementation cost to draw out the strength and shortcomings of individual methods that will come to aid to the companies or researchers for establishing the applicability and appropriateness of such method for their concerned domain. | Soham Dutta Pradip Kumar Sadhu M.Jaya Bharata Reddy Dusmanta Kumar Mohanta | 2018 | Protection and Control of Modern Power Systems2018，3，1： | 1 |
| 10 | Multilevel image thresholding based on 2D histogram and maximum Tsallis entropy-a differential evolution approach显示文摘 | Soham S Swagatam D | 2012 | IEEE Transactions on Image Processing2012，22，12： | 1 |
| 11 | Agent-oriented Programming显示文摘 | Soham Y | 1993 | Artificial Intelligence1993，60，： | 1 |
| 12 | Anterior glottic web显示文摘 | RICHARD J V SOHAM R | 2008 | Ear Nose Throat J2008，87，： | 1 |
| 13 | Nonlinear bending response of laminated composite spherical shell panel with system randomness subjected to hygro-thermo-mechanical loading显示文摘 | Achchhe Lal B.N. Singh Soham Anand | 2011 | International Journal of Mechanical Sciences2011，，10： | 1 |
| 14 | Expanding nail or expanding femur?An adverse event with the expandable Intramedullary显示文摘 | Soham G Nicholas D R Chellappan K S | 2010 | Acta Orthop TraumatolTurc2010，44，2： | 1 |
| 15 | Food Imports in India:Prospects,Issues and Way Forward显示文摘India is one of the fastest growing markets in the world.Among the various sectors contributing to the growth of the economy,food is one of the fastest growing sectors owing to factors such as a large population base,rising middle-class,increase in per-capita income,and greater consumer awareness.Demand for imported food products is increasing due to factors such as reduction in tariffs,changes in consumer preferences and growing adaptability to international cuisine.Several initiatives have been taken by the Indian government in recent years to improve the ease of doing business and reduce the compliance burden through use of technology.Despite these initiatives,India’s ranking compared to other countries in some selective indicators such as documentary and border compliance and logistics performance is quite low.To improve ease of doing business,reduce cost and time taken in importing food products,and improve India’s ranking in logistics performance indicators,there is an urgent need for backend process and information technology(IT)integration across the agencies involved in the import clearance process.Given this background,the objective of this paper is to(a)provide an overview of the food import clearance process in India,(b)identify issues in the import process and(c)make recommendations on how to streamline the process using technology and automation.The paper is based on a survey of key stakeholders engaged in the food import clearance process.Based on a primary survey of 150 stakeholders in the United Kingdom and India,this paper finds that while India is an attractive market for importing food;low penetration of technology in the food import clearance process,lack of inter-agency coordination,and lack of risk management systems impedes the ease of importing food products into India.This paper recommends that in order to enhance ease of doing business,especially for SMEs,there is need to reduce procedural barriers by implementing technology and automation-oriented solutions,and a robust risk management system.In addition,there is a need to conduct continuous regulatory impact analysis to assess the time and cost reduction in importing food into India. | Arpita Mukherjee Divya Satija Angana Parashar Sarma Soham Sinha | 2019 | Journal of Economic Science Research2019，2，3： | 0 |
| 16 | An Anisotropic Hyperelastic Inflated Toroidal Membrane in Lateral Contact with Two Flat Rigid Plates显示文摘The present paper studies the contact problem of an inflated toroidal nonlinear anisotropic hyperelastic membrane laterally pressed between two flat rigid plates.The material is assumed to be homogeneous,and an anisotropic term is included in the incompressible Mooney–Rivlin hyperelastic model.Initially,two annular-shaped flat membranes,bonded at both equators,are considered in an undeformed state,which results in a toroidal geometry upon uniform internal pressurization.The contact problem of the inflated torus laterally pressed between two flat parallel plates is solved.Two different contact conditions,namely frictionless contact and no-slip contact,are considered within the contact region.The enclosed amount of gas within the inflated membrane is considered to be constant during the solution of the contact problem,which is solved in a quasi-static manner.In the case of no-slip contact,the stretch locking has been observed,and the frictionless contact causes the free flow of material points.The membrane’s stiffness increases with increasing anisotropic,material,and geometric parameters depicted in the force versus displacement curve under contact conditions. | Satyajit Sahu Soham Roychowdhury | 2022 | Acta Mechanica Solida Sinica2022，35，6： | 0 |
| 17 | Pancreatic fat in type 2 diabetes:Causal or coincidental?显示文摘Type 2 diabetes(T2D)is a multifactorial metabolic disorder affecting more than 450 million people across the globe.With the increasing prevalence of T2D and obesity,the role of fat accumulation at sites other than subcutaneous adipose tissue has received significant attention in the pathophysiology of T2D.Over the past decade and a half,a pressing concern has emerged on investigating the association of pancreatic fat accumulation or pancreatic steatosis with the development of disease.While a few reports have suggested a possible association between pancreatic fat and T2D and/or impaired glucose metabolism,a few reports suggest a lack of such association.Pancreatic fat has also been linked with genetic risk of developing T2D,prediabetes,reduced insulin secretion,and beta cell dysfunction albeit some confounding factors such as age and ethnicity may affect the outcome.With the technological advancements in clinical imaging and progress in assessment of pancreatic beta cell function,our understanding of the role of pancreatic fat in causing insulin resistance and development of various etiologies of T2D has significantly improved.This review summarizes various findings on the possible association of pancreatic fat accumulation with the pathophysiology of T2D. | Soham Mukherjee Deep Maheshwari Rimesh Pal Naresh Sachdeva | 2023 | World Journal of Meta-Analysis2023，11，3： | 0 |
| 18 | Harvesting Asian Prosperity Together显示文摘The agricultural sector was a highlight of the government work report delivered at the opening of the first session of the 14th National People's Congress in Beijing.The agricultural links between India and China could foster optimism on strengthening bilateral ties. | Soham Shripad Kakade | 2023 | 中印对话(英文版)2023，，1： | 0 |
| 19 | 一种用于线粒体受激辐射损耗超分辨成像的新型探针显示文摘受激辐射损耗(stimulated emission depletion,STED)显微技术通过巧妙的光学设计,利用纯光学的方法突破了光学衍射极限,空间分辨率达到纳米量级,并保留了荧光显微的许多优点.然而,高的损耗光强度限制了STED显微技术的广泛应用,尤其在活细胞成像方面.本文找到了一种新型的具有良好线粒体靶向性的STED探针,具有较强的抗光漂白特性和较低的饱和擦除光强度3.5 mW(1.1 MW·cm–2),利用该探针最高可获得62 nm的空间分辨率,为活细胞线粒体STED超分辨成像提供了新的手段. | 张佳 Samanta Soham 王佳林 王璐玮 杨志刚 严伟 屈军乐 | 2020 | 物理学报2020，69，16： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员