| 1 | Predictors of malaria rapid diagnostic test positivity in a high burden area of Paletwa Township, Chin State in Western Myanmar显示文摘Background:Despite major reductions in malaria burden across Myanmar,clusters of the disease continue to persist in specific subregions.This study aimed to assess the predictors of test positivity among people living in Paletwa Township of Chin State,an area of persistently high malaria burden.Methods:Four villages with the highest malaria incidence from Paletwa Town ship were purposively selected.The characteristics of 1045 subjects seeking malaria diagnosis from the four assigned village health volunteers from January to December,2018 were retrospectively analyzed.Their household conditions and surroundings were also recorded using a checklist.Descriptive statistics and logistic regression models were applied to investigate potential associations between individual and household characteristics and malaria diagnosis.Results:In 2017,the Paletwa township presented 20.9%positivity and an annual parasite index of 46.9 cases per 1000 people.Plasmodium falciparum was the predominant species and accounted for more than 80.0%of all infections.Among 1045 people presenting at a clinic with malaria symptoms,31.1% were diagnosed with malaria.Predictors for test positivity included living in a hut[adjusted odds ratios(aOR):2.3,95%confidence intervals(CI ):1.2-4.6],owning farm animals(aOR:1.7,95% CI:1.1-3.6),using non-septic type of toilets(aOR:1.9,95%CI:1.1-8.4),presenting with fever(aOR:1.9,95%CI:1.1-3.0),having a malaria episode within the last year(aOR:2.9,95%CI:1.45.8),traveling outside the village in the previous 14 days (aOR:4.5,95%CI:1.5-13.4),and not using bed nets(aOR:3.4,95%CI:2.3-5.1).There were no statistically significant differences by age or gender in this present analysis.Conclusions:The results from this study,including a high proportion of P.falciparum infections,little difference in age,sex,or occupation,suggest that malaria is a major burden for these study villages.Targeted health education campaigns should be introduced to strengthen synchronous diagnosis-seeking behaviors,tighten treatment adheren ce,receiving a diagnosis after traveling to endemic regi ons,and using bed nets properly.We suggest in creased surveillance,early diagnosis,and treatment efforts to control the disease and then to consider the local elimination. | Pyae Linn Aung Myat Thu Soe Thit Lwin Oo Aung Khin AungThi Yan Zhao Yarning Cao Liwang Cui Myat Phone Kyaw Daniel M.Parker | 2021 | Infectious Diseases of Poverty2021，10，1： | 0 |
| 2 | Observed characteristics of flow,water mass,and turbulent mixing in the Preparis Channel显示文摘Preparis Channel is the very important exchange path of energy and materials between the northern Bay of Bengal and Andaman Sea(AS).A set of hydrographic measurements,a microstructure profiler,and a deep mooring were used to determine the characteristics of water masses,turbulent mixing,and flows in the Preparis Channel.The unprecedented short-term mooring data reveal that a deep current in the deep narrow passage(below 400 m)of the Preparis Channel flows toward the Bay of Bengal(BoB)with a mean along-stream velocity of 25.26 cm/s at depth of 540 m;above the deep current,there are a relatively weak current flows toward the AS with a mean along-stream velocity of 15.46 cm/s between 500 m and 520 m,and another weak current flows toward the BoB between 430 m and 500 m.Thus,a sandwiched vertical structure of deep currents(below 400 m)is present in the Preparis Channel.The volume transport below 400 m is 0.06 Sv(1 Sv=106 m^(3)/s)from the AS to the BoB.In the upper layer(shallower than 300 m),the sea water of the AS is relatively warmer and fresher than that in the BoB,indicating a strong exchange through the channel.Microstructure profiler observations reveal that the turbulent diffusivity in the upper layer of the Preparis Channel reaches O(10−4 m^(2)/s),one order larger than that in the interior of the BoB and over the continental slope of the northern AS.We speculate that energetic high-mode internal tides in the Preparis Channel contribute to elevated turbulent mixing.In addition,a local“hotspot”of turbidity is identified at the deep mooring site,at depth of about 100 m,which corresponds to the location of elevated turbulent mixing in the Preparis Channel. | Ruijie Ye Feng Zhou Xiao Ma Dingyong Zeng Feilong Lin Hongliang Li Chenggang Liu Soe Moe Lwin Hlaing Swe Win Soe Pyae Aung | 2023 | Acta Oceanologica Sinica2023，42，2： | 0 |
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