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| 1 | JAK-STAT pathway in carcinogenesis:Is it relevant to cholangiocarcinoma progression?显示文摘The features of JAK-STAT signaling in liver cells are discussed in the current review. The role of this signaling cascade in carcinogenesis is accentuated. The possible involvement of this pathway and alteration of its elements are compared for normal cholangiocytes, cholangiocarcinoma predisposition and development. Prolactin and interleukin-6 are described in detail as the best studied examples. In addition, the non-classical nuclear translocation of cytokine receptors is discussed in terms of its possible implication to cholangiocarcinoma development. | Olga V Smirnova Tatiana Yu Ostroukhova Roman L Bogorad | 2007 | World Journal of Gastroenterology2007，13，48： | 14 |
| 2 | Chemotherapy of glioblastoma in rats using doxorubicin - loaded nanoparticles显示文摘Glioblastomas belong to the most aggressive human cancers with short survival times.Due to the blood-brainbarrier,they are mostly inaccessible to traditional chemotherapy.We have recently shown that doxorubicin boundto polysorbate-coated nanoparticles crossed the intact blood-brain barrier,thus reaching therapeutic concentra-tions in the brain.Here,we investigated the therapeutic potential of this formulation of doxorubicin in vivo using ananimal model created by implantation of 101/8 glioblastoma tumor in rat brains.Groups of 5-8 glioblastoma- | Steiniger SC Kreuter J Khalansky AS Skidan IN Bobruskin I Smirnova ZS Severin SE Uhl R Kock M Geiger KD Gelperina SE | 2004 | 中国神经肿瘤杂志2004，2，1： | 13 |
| 3 | Room-temperature lasing from nanophotonic topological cavities显示文摘The study of topological phases of light underpins a promising paradigm for engineering disorder-immune compact photonic devices with unusual properties.Combined with an optical gain,topological photonic structures provide a novel platform for micro-and nanoscale lasers,which could benefit from nontrivial band topology and spatially localized gap states.Here,we propose and demonstrate experimentally active nanophotonic topological cavities incorporating Ⅲ-Ⅴ semiconductor quantum wells as a gain medium in the structure.We observe room-temperature lasing with a narrow spectrum,high coherence,and threshold behaviour.The emitted beam hosts a singularity encoded by a triade cavity mode that resides in the bandgap of two interfaced valley-Hall periodic photonic lattices with opposite parity breaking.Our findings make a step towards topologically controlled ultrasmall light sources with nontrivial radiation characteristics. | Daria Smirnova Aditya Tripathi Sergey Kruk Min-Soo Hwang Ha-Reem Kim Hong-Gyu Park Yuri Kivshar | 2020 | Light(Science & Applications)2020，9，1： | 6 |
| 4 | Nontrivial coupling of light into a defect:the interplay of nonlinearity and topology显示文摘The flourishing of topological photonics in the last decade was achieved mainly due to developments in linear topological photonic structures.However,when nonlinearity is introduced,many intriguing questions arise.For example,are there universal fingerprints of the underlying topology when modes are coupled by nonlinearity,and what can happen to topological invariants during nonlinear propagation?To explore these questions,we experimentally demonstrate nonlinearity-induced coupling of light into topologically protected edge states using a photonic platform and develop a general theoretical framework for interpreting the mode-coupling dynamics in nonlinear topological systems.Performed on laser-written photonic Su-Schrieffer-Heeger lattices,our experiments show the nonlinear coupling of light into a nontrivial edge or interface defect channel that is otherwise not permissible due to topological protection.Our theory explains all the observations well.Furthermore,we introduce the concepts of inherited and emergent nonlinear topological phenomena as well as a protocol capable of revealing the interplay of nonlinearity and topology.These concepts are applicable to other nonlinear topological systems,both in higher dimensions and beyond our photonic platform. | Shiqi Xia Dario Jukic Nan Wang Daria Smirnova Lev Smirnov Liqin Tang Daohong Song Alexander Szameit Daniel Leykam Jingjun Xu Zhigang Chen Hrvoje Buljan | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 5 | 苏云金芽孢杆菌达姆斯塔特亚种新菌株Btd61的鉴定及其晶体蛋白基因型的初步分析显示文摘用选择性培养基从舞毒蛾(Lymantriadispar)死虫体中分离到苏云金芽孢杆菌新菌株B-61,经分类鉴定属苏云金芽孢杆菌达姆斯塔特亚种(Bacillusthuringiensissubsp.darmstadiensis),简称Btd61.该菌株有8种质粒,4种晶体蛋白,合成二锥体小晶体和不规则大晶体2种伴孢晶体颗粒,对大蜡螟(Galeriamelonela)和舞毒蛾皆具强毒性.Btd61携带B1型的溶原性噬菌体,但又对B1型的Tb10噬菌体有抗性. | 林风 连云阳 程元荣 Smirnova TA Minenkova IB Azizbekyan RR | 1996 | 福建农业大学学报1996，25，2： | 3 |
| 6 | A primer on stable parameter estimation and forecasting in epidemiology by a problem-oriented regularized least squares algorithm显示文摘Public health officials are increasingly recognizing the need to develop disease-forecasting systems to respond to epidemic and pandemic outbreaks.For instance,simple epidemic models relying on a small number of parameters can play an important role in characterizing epidemic growth and generating short-term epidemic forecasts.In the absence of reliable information about transmission mechanisms of emerging infectious diseases,phenomenological models are useful to characterize epidemic growth patterns without the need to explicitly model transmission mechanisms and the natural history of the disease.In this article,our goal is to discuss and illustrate the role of regularization methods for estimating parameters and generating disease forecasts using the generalized Richards model in the context of the 2014e15 Ebola epidemic in West Africa. | Alexandra Smirnova Gerardo Chowell | 2017 | Infectious Disease Modelling2017，2，2： | 2 |
| 7 | Liquid phase epitaxy of SiC in the system Si-Tb-SiC by temperature gradient zone melting (Ⅰ) Investigation of solubilities in the system Si-Tb-SiC显示文摘 | TAIROV Y M SMIRNOVA N S KALNIN A A | 1986 | Crystal Research and Technology1986，21，12： | 1 |
| 8 | A feedback loop comprising lin-28 and let-7 controls pre-let-7maturation during neural stem-cell commitment 显示文摘 | Rybak A Fuchs H Smirnova L Brandt C Pohl EE Nitsch R etal | 2008 | Nat CellBioi2008，10，8： | 1 |
| 9 | Treatment regeneration of used lube oils with inorganic membranes显示文摘 | Minion V N Smirnova E B Smirnov B N | 2004 | Chemistry and Technology of Fuels and Oils2004，5，： | 1 |
| 10 | Thermal analysis and design of a volumetric solar absorber depending on the porosity显示文摘 | M.I. Roldán O. Smirnova T. Fend J.L. Casas E. Zarza | 2014 | Renewable Energy2014，，： | 1 |
| 11 | Thiocyanate decomposition under aerobic and oxygen-free conditions by the aboriginal bacterial community isolated from the waste water of a metallurgical works显示文摘 | N. V. Grigor’eva Yu. V. Smirnova L. E. Dulov | 2009 | Microbiology2009，，4： | 1 |
| 12 | Peculiarities of the rheological behavior and structure formation of aluminum under deformation at near-solidus temperatures显示文摘This paper deals with a peculiar rheological behavior of aluminum at near-solidus temperatures. It has been experimentally established that there is an inverse strain rate dependence of strain resistance at temperatures ranging between 560 and 640°С and strain rates ranging from 0.06 to 1.2 s^(-1). Electron backscatter diffraction analysis has shown that at temperatures ranging between 540 and 640°С and strain rates ranging from 0.06 to 0.1 s^(-1), the main process of softening is dynamic polygonization, resulting in in situ recrystallization. At higher strain rates, ranging between 0.8 and 1.2 s~(^(-1)), and temperatures ranging between 560 and 640°С, the recovery is dynamic. This unusual behavior of the mechanism of softening and the presence of the inverse strain rate dependence of strain resistance can be explained by blocking the motion of free dislocations by foreign atoms, which occurs at strain rates ranging between 0.06 and 0.1 s^(-1). This process results in dislocation pile-up, thereby causing in situ recrystallization. At strain rates exceeding 0.16 s^(-1), there is no intensive blocking of dislocations, leading to a direct strain rate dependence of strain resistance. | A. S. Smirnov A. V. Konovalov G. A. Belozerov V. P. Shveikin E. O. Smirnova | 2016 | International Journal of Minerals,Metallurgy and Materials2016，23，5： | 1 |
| 13 | Defective LPS signaling in C3H/ HeJ and C57BL/ 10ScCr mice: mutations in Tlr4 gene显示文摘 | Poltorak A He X Smirnova I | 1998 | Science1998，282，5396： | 1 |
| 14 | Phylogenetic variation and polymorphism at the toll-like receptor4 locus(TLR4)显示文摘 | Smirnova I Poltorak A Chan E K | 2000 | Genome Biol2000，1，1： | 1 |
| 15 | Phase transitions and glasslike behavior in Sr1-xBaxTiO3显示文摘 | LEMANOV V V SMIRNOVA E P SYRNIKOV P P | 1996 | Phys Rev B1996，54，5： | 1 |
| 16 | ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells显示文摘 | Smirnova E Goldberg E B Makarovs K S | 2006 | EMBO Rep2006，7，1： | 1 |
| 17 | Spectral interferences from polyatomic barium ions in inductively coupled plasma mass spectrometry显示文摘 | Smirnova E V Mysovskaya I N Lozhkin V I | 2006 | Journal of Applied Spectroscopy2006，73，6： | 1 |
| 18 | Branchiomyces-like infection in a cultured tilapia (Oreochromis hybrid, Cichlidae) 显示文摘 | PAPERNA I SMIRNOVA M | 1997 | Disease of Aquatic Organisms1997，31，： | 1 |
| 19 | Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice:mutations in Tlr4 gene显示文摘 | Poltorak A He X Smirnova I | 1998 | Science1998，282，： | 1 |
| 20 | The use of ion-exchange membranes in the hydrometallurgy of uranium显示文摘 | Laskorin B N Smirnova N M | 1962 | The Soviet Journal of Atomic Energy1962，10，4： | 1 |
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