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| 1 | Cardiac and non-cardiac causes of T-wave inversion in the precordial leads in adult subjects: A Dutch case series and review of the literature显示文摘AIM: To describe the electrocardiographic(ECG) phenomena characterized by T-wave inversion in the precordial leads in adults and to highlight its differential diagnosis. METHODS: A retrospective chart review of 8 adult patients who were admitted with ECG T-wave inversion in the anterior chest leads with or without prolongation of corrected QT(QTc) interval. They had different clinical conditions. Each patient underwent appropriate clinical assessment including investigation for myocardial involvement. Single and multimodality noninvasive, semi-invasive and invasive diagnostic approach were used to ascertain the diagnosis. The diagnostic assessment included biochemical investigation, cardiac and abdominal ultrasound, cerebral and chest computed tomography, nuclear medicine and coronary angiography.RESULTS: Eight adult subjects(5 females) with a mean age of 66 years(range 51 to 82) are analyzed. The etiology of T-wave inversion in the precordial leads were diverse. On admission, all patients had normal blood pressure and the ECG showed sinus rhythm. Five patients showed marked prolongation of the QTc interval. The longest QTc interval(639 ms) was found in the patient with pheochromocytoma. Giant T-wave inversion(≥ 10 mm) was found in pheochromocytoma followed by electroconvulsive therapy and finally ischemic heart disease. The deepest T-wave was measured in lead V3(5 ×). In 3 patients presented with mild T-wave inversion(patients 1, 5 and 4 mm), the QTc interval was not prolonged(432, 409 and 424 msec), respectively.CONCLUSION: T-wave inversion associated with or without QTc prolongation requires meticulous history taking, physical examination and tailored diagnostic modalities to reach rapid and correct diagnosis to establish appropriate therapeutic intervention. | Salah AM Said Rene Bloo Ramon de Nooijer Andries Slootweg | 2015 | World Journal of Cardiology2015，7，2： | 7 |
| 2 | Coronary artery disease in congenital single coronary artery in adults:A Dutch case series显示文摘AIM:To assess the current diagnostic and therapeutic management and the clinical implications of congenital single coronary artery(SCA) in adults.METHODS:We identified 15 patients with a SCA detected from four Dutch angiography centers in the period between 2010 and 2013.Symptomatic patients who underwent routine diagnostic coronary angiography(CAG) for suspected coronary artery disease and who incidentally were found to have isolated SCA were analyzed.RESULTS:Fifteen(7 females) with a mean age of 58.5 ± 13.78 years(range 43-86) had a SCA.ConventionalCAG demonstrated congenital isolated SCA originating as a single ostium from the right sinus of Valsalva in 6 patients and originating from the left in 9 patients.Minimal to moderate coronary atherosclerotic changes were found in 4,and severe stenotic lesions in another 4 patients.Seven patients were free of coronary atherosclerosis.Runs of non-sustained ventricular tachycardia were documented in 2 patients,one of whom demonstrated transmural ischemic changes on presentation.Myocardial perfusion scintigraphic evidence of transmural myocardial ischemia was found in 1 patient due to kinking and squeezing of the SCA with an interarterial course between the aorta and pulmonary artery.Multi-slice computed tomography(MSCT) was helpful to delineate the course of the anomalous artery relative to the aorta and pulmonary artery.Percutaneous coronary intervention was successfully performed in 3 patients.Eight patients were managed medically.Arterial bypass graft was performed in 4 patients with the squeezed SCA.CONCLUSION:SCA may be associated with transient transmural myocardial ischemia and aborted sudden death in the absence of coronary atherosclerosis.The availability and sophistication of MSCT facilitates the delineation of the course of a SCA.We present a Dutch case series and review of the literature. | Salah AM Said Willem G de Voogt Suat Bulut Jacques Han Peter Polak Rogier LG Nijhuis Jeroen W op den Akker Andries Slootweg | 2014 | World Journal of Cardiology2014，6，4： | 3 |
| 3 | Economical regula-tion power through load shifting with smart energy appli-ances显示文摘 | Vlot M C Knigge J D Slootweg J G | 2013 | IEEE Trans on Smart Grid2013，4，3： | 1 |
| 4 | General Model for Representing Variable Speed Wind Turbines inPower System Dynamics Simulations显示文摘 | Slootweg J G de Haan S W H Polinder H | 2003 | IEEE Transactions on Power Systems2003，18，1： | 1 |
| 5 | Estrogen enhances growth hormone receptor expression and growth hormone action in rat osteosarcoma cells and human osteoblast-like cells 显示文摘 | Slootweg M C Swolin D Netelenbos J C | 1997 | Journal of Endocrinology1997，155，： | 1 |
| 6 | Modelling wind turbines for power system dynamics simulations 显示文摘 | SLOOTWEG J G KLING W L | 2004 | Wind Engineering2004，28，1： | 1 |
| 7 | General model for representing variable speed wind turbines in power system dynamics simulations显示文摘 | SLOOTWEG J G de HAAN S W H POLINDER H | 2003 | IEEE Trans on Power Systems2003，18，1： | 1 |
| 8 | General model for representing variable speed wind turbines in power system dynamics simulations 显示文摘 | SLOOTWEG J G DE HAAN S W H POLINDOER H et d | 2003 | IEEE Transactions on Power Systems2003，18，1： | 1 |
| 9 | General model for representing variable speed wind turbines in power system dynamics simulations 显示文摘 | Slootweg J G Polinder H Kling W L | 2003 | IEEE Transactions on Power Systems2003，18，1： | 1 |
| 10 | General model for representing variable speed wind turbines in power system dynamics simulations显示文摘 | SLOOTWEG J G | 2003 | IEEE Trans on Power Systems2003，18，1： | 1 |
| 11 | Modeling of large wind farms in power system simulations显示文摘 | SLOOTWEG J G KLING W L | 2002 | IEEE Trans on Power Systems2002，10，2： | 1 |
| 12 | A generic approach to integrate biodiversity considerations in screening and scooping for EIA显示文摘 | SLOOTWEG R KOLHOFF A | 2003 | Environmental Impact Assessment Review2003，23，6： | 1 |
| 13 | Growth hormone and bone显示文摘 | OHLSSON C BENGTSSON BA ISAKSSON OG Slootweg MC | 1998 | Endocr Rev1998，19，： | 1 |
| 14 | The impact of large scale wind power generation on power system oscillations 显示文摘 | Slootweg J G Kling W L | 2003 | Electric Power System Research2003，67，1： | 1 |
| 15 | A generic approach to integrate biodiversity considerations in screening and scooping for EIA显示文摘 | ROEL SLOOTWEG AREND KOLHOFF | 2003 | Environmental Impact Assessment Review2003，，23： | 1 |
| 16 | Modeling and analyzing impacts of wind power on transient stability of power systems显示文摘 | Kling W L | 2001 | Wind Engineering2001，25，6： | 1 |
| 17 | Basic op-eration principles and electrical conversion systems of wind turbines显示文摘 | Plinder H de Haan S W H Slootweg J G | 2005 | EPEJ2005，15，： | 1 |
| 18 | Dynamic modelling of a wind turbine with doubly fed induction generator显示文摘 | Slootweg J G Kling W L Polinder H | 2001 | Power Engíneeríng Society Summer Meeting IEEE2001，，01： | 1 |
| 19 | Histologie changes after vertebmplasty显示文摘 | Oner FC Slootweg PJ | 2004 | J Bone Joint Surg Am2004，86，6： | 1 |
| 20 | The status of the resection margin as a prognostic factor in the treatment of head and neck carcinoma 显示文摘 | Ravasz LA Slootweg P J Hordijk G J | 1991 | J Craniomaxillofac Surg1991，19，7： | 1 |
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