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| 1 | Microsecond scale vibrational spectroscopic imaging by multiplex stimulated Raman scattering microscopy显示文摘Real-time vibrational spectroscopic imaging is desired for monitoring cellular states and cellular processes in a label-free manner.Raman spectroscopic imaging of highly dynamic systems is inhibited by relatively slow spectral acquisition on millisecond to second scale.Here,we report microsecond scale vibrational spectroscopic imaging by lock-in free parallel detection of spectrally dispersed stimulated Raman scattering signal.Using a homebuilt tuned amplifier array,our method enables Raman spectral acquisition,within the window defined by the broadband pulse,at the speed of 32 μs and with close to shot-noise limited detection sensitivity.Incorporated with multivariate curve resolution analysis,our platform allows compositional mapping of lipid droplets in single live cells,observation of intracellular retinoid metabolism,discrimination of fat droplets from protein-rich organelles in Caenorhabditis elegans,spectral detection of fast flowing tumor cells and monitoring drug diffusion through skin tissue in vivo.The reported technique opens new opportunities for compositional analysis of cellular compartment in a microscope setting and high-throughput spectral profiling of single cells in a flow cytometer setting. | Chien-Sheng Liao Mikhail N Slipchenko Ping Wang Junjie Li Seung-Young Lee Robert A Oglesbee Ji-Xin Cheng | 2015 | Light(Science & Applications)2015，4，1： | 8 |
| 2 | Stimulated Raman scattering imaging by continuous-wave laser excitation 显示文摘 | Hu C R Slipchenko M N Wang P | 2013 | Optics letters2013，38，9： | 1 |
| 3 | High power CW (16W) and pulse (145W) laser diodes based on quantum well heterostructures显示文摘 | Ilya S. Tarasov Nikita A. Pikhtin Sergey O. Slipchenko Zinaida N. Sokolova Dmitry A. Vinokurov Kirill S. Borschev Vladimir A. Kapitonov Maxim A. Khomylev Andrey Yu. Leshko Andrey V. Lyutetskiy Alexey L. Stankevich | 2007 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2007，，4： | 1 |
| 4 | Evolution of the vibrational spectrum of ammonia from single molecule to bulk 显示文摘 | M N Slipchenko B G Sartakov A F Vilesov | 2008 | J Chem Phys2008，128，13： | 1 |
| 5 | Effective fragment potential study of the interaction of DNA bases显示文摘 | SMITH Q A GORDON M S SLIPCHENKO L V | 2011 | J Phys Chem A2011，115，11： | 1 |
| 6 | Coupling CARS with Multiphoton Fluorescence and High Harmonic Generation Imaging Modalities Using a Femtosecond Laser Source显示文摘 | CHEN HONG-TAO SLIPCHENKO M N ZHU JIAN-BIN | 2009 | Proc SPIE CARS Microscopy Ⅳ2009，7183，71： | 1 |
| 7 | Infrared intensity in small ammonia and water clusters显示文摘 | Mikhail N Slipchenko Kirill E | 2006 | Journal of Chemical Physics2006，124，24： | 1 |
| 8 | Mechanisms of epi- detected stimulated Raman scattering microscopy 显示文摘 | Wang P Slipchenko M N Zhou B | 2012 | Se- lected Topics in Quantum Electronics IEEE2012，18，1： | 1 |
| 9 | 稳定的大气边界层雷达探测信号回波分量的波谱分析显示文摘为推动研究大气边界层声学探测方法的发展,解决信息抽样问题,多数研究使用以正命题的解为基础的计算方法。然而在推导论证正命题的过程中不可避免地需要使用简便方法,对获得的解具有一定的影响。通过以逆命题的解为基础,确定声波探测大气边界层(ABL)回波信号的波谱分量组成。计算声波反射系数分布、可允许近似值以及稳定的大气边界层反射场,并对回波信号的波谱宽度进行了分析。结果表明,此方法可大幅缩小雷达接收设备的信号带宽,这将使其能量势得以提升。 | 刘畅 Panchenko A.Yu. Slipchenko M.I. | 2018 | 黑龙江八一农垦大学学报2018，30，1： | 0 |
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